Melia Azedarach Leaf/Stem Extract: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Melia Azedarach Leaf/Stem Extract?

Melia Azedarach Leaf/Stem Extract comes from the leaves and young stems of the chinaberry tree, a fast-growing species native to Asia and now found in many warm regions. The plant has long been valued in folk practices for its soothing and conditioning qualities, which led cosmetic chemists to explore it for skin care. The extract contains a mix of plant sugars, fatty acids and small amounts of proteins that help bind water and soften skin. To make the ingredient, freshly collected leaves and stems are cleaned, ground and then soaked in a food-grade solvent or glycerin. After the plant matter is filtered out, the liquid is gently concentrated to keep the active compounds intact. You will often spot Melia Azedarach Leaf/Stem Extract in moisturizers, hydrating masks, lightweight lotions, anti-aging serums and after-sun gels, where it lends a cushiony feel and moisture boost.

Melia Azedarach Leaf/Stem Extract’s Cosmetic Benefits/Uses

This plant extract adds two key actions to skin care formulas:

  • Emollient: Smooths rough patches by filling in tiny gaps on the skin surface, leaving a soft, supple finish and helping other actives spread more evenly
  • Humectant: Draws water from the environment and deeper skin layers to the outer surface, keeping skin hydrated for longer and reducing the look of fine lines caused by dryness

Who Can Use Melia Azedarach Leaf/Stem Extract

This extract is generally well tolerated by all major skin types including dry, normal, oily and combination. Its light texture and water-binding ability make it especially helpful for dehydrated or rough skin, while its non-occlusive nature means it will not weigh down oily or acne-prone complexions. Sensitive skin can usually use it without issues because the extract is free of fragrance allergens and harsh acids.

Because the ingredient comes from a plant and no animal derivatives are involved in its processing, it is suitable for both vegans and vegetarians. Most suppliers also certify it as cruelty free.

Current research shows no specific hormonal or systemic activity, so products containing Melia Azedarach Leaf/Stem Extract are considered safe for women who are pregnant or breastfeeding. Still, this is not medical advice and anyone who is pregnant or nursing should run any skincare product past a qualified doctor to be on the safe side.

The extract does not increase photosensitivity, so there is no special need to avoid sunlight beyond normal daily SPF recommendations.

Potential Side Effects/Adverse Reactions

Side effects and reactions to the topical application of Melia Azedarach Leaf/Stem Extract can vary from person to person. The following list covers potential reactions, but they are unlikely to be the typical user experience when the ingredient is properly formulated in a finished product.

  • Mild redness or tingling in very sensitive skin
  • Contact dermatitis triggered by an individual allergy to chinaberry tree compounds
  • Eye irritation if the product accidentally gets into the eyes
  • Rare cross-reactivity in people highly allergic to other Meliaceae family plants

If any irritation, swelling or persistent discomfort occurs discontinue use and consult a healthcare professional.

Comedogenic Rating

Rating: 1/5 (very low)

Melia Azedarach Leaf/Stem Extract is mostly composed of lightweight plant sugars and gentle fatty acids that absorb quickly without forming a heavy film. It lacks the thick oils or waxes typically linked to clogged pores and is usually used in modest amounts within formulas. These factors keep its pore-clogging potential minimal, giving it a score of 1.

The extract is therefore considered suitable for those prone to acne or breakouts.

If layered under very rich occlusive products the overall routine could feel heavier, so adjust accompanying products accordingly.

Summary

Melia Azedarach Leaf/Stem Extract works as an emollient that smooths rough spots and as a humectant that attracts water to the skin surface, thanks to its natural mix of water-binding sugars, softening fatty acids and small proteins.

Although not as mainstream as aloe or hyaluronic acid it is steadily gaining fans among brands that favor plant-based hydrators.

The ingredient is regarded as safe for most users with a very low chance of irritation or breakouts. Still, skin can be unpredictable so perform a quick patch test when introducing any new product containing this extract to ensure it agrees with you.

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