Methoxy Peg-7 Dehydrocholesteryl Succinate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Methoxy Peg-7 Dehydrocholesteryl Succinate?

Methoxy Peg-7 Dehydrocholesteryl Succinate is a lab-made ester created by linking a cholesterol-like molecule with succinic acid and a short chain of polyethylene glycol. The cholesterol part is usually sourced from lanolin or plant sterols, giving the ingredient a waxy backbone that mixes well with both oils and water. First introduced in the 1990s, it found a place in cosmetics thanks to its ability to multitask as a mild UV absorber, antioxidant and hair softener.

To make it, chemists start with dehydrocholesterol, react it with succinic anhydride to form a succinate, then attach a small PEG chain and a methoxy cap. The result is a stable, fluid ingredient that slips easily into lotions, creams and sprays without leaving a heavy feel.

You will usually spot Methoxy Peg-7 Dehydrocholesteryl Succinate in facial moisturizers, daily sunscreens, anti-aging serums, hair masks, leave-in conditioners, styling creams and color-protection shampoos. Its broad compatibility lets formulators use it in everything from light gels to rich balms.

Methoxy Peg-7 Dehydrocholesteryl Succinate’s Cosmetic Benefits/Uses

Below are the main ways this ingredient supports your skin and hair care products

  • Antioxidant – Helps neutralize free radicals that can break down oils, fragrances and pigments, keeping the formula stable and supporting healthier looking skin
  • Hair Conditioning – Forms a thin smoothing layer over each strand so hair feels softer, looks shinier and detangles more easily
  • UV Filter – Absorbs a portion of UV rays which boosts the overall sun protection of daytime products and helps prevent color fade in hair care

Who Can Use Methoxy Peg-7 Dehydrocholesteryl Succinate

This multifunctional ester is generally well tolerated by all skin types including oily, combination, dry and mature skin. Its light, non-greasy feel makes it comfortable even for easily congested skin while the soothing cholesterol backbone can be beneficial to dry or compromised barriers. Sensitive skin usually handles it well thanks to its low irritation profile, although anyone with a known sensitivity to lanolin derivatives should proceed with caution.

Because the cholesterol portion can be sourced from wool grease or plant sterols, the ingredient may or may not be animal derived. Strict vegans will want confirmation from the brand that a plant-based grade was used. Vegetarians who are comfortable with lanolin derivatives typically view it as acceptable.

No specific concerns have been raised for pregnant or breastfeeding women using this ingredient topically. It is not known to penetrate deeply or interfere with hormones. Still, this is not medical advice and anyone who is pregnant or nursing should clear all skincare purchases with a qualified healthcare provider.

Methoxy Peg-7 Dehydrocholesteryl Succinate does not cause photosensitivity. In fact, it lends mild UV filtering support, so it will not make skin more reactive to sunlight.

Potential Side Effects/Adverse Reactions

Individual responses to Methoxy Peg-7 Dehydrocholesteryl Succinate can differ. The issues listed below are possible yet uncommon if the finished product has been formulated and preserved correctly.

  • Mild skin irritation in people who are sensitive to lanolin derivatives or polyethylene glycol compounds
  • Contact allergy presenting as redness itching or small bumps, most often in those with a history of wool alcohol allergy
  • Eye stinging if high concentrations of a product run into the eyes during application or rinsing
  • Scalp buildup or limp hair when used in very rich leave-in formulas on fine hair types

If any discomfort or reaction develops discontinue use and seek advice from a medical professional or pharmacist.

Comedogenic Rating

Rating: 1/5

Methoxy Peg-7 Dehydrocholesteryl Succinate is largely water dispersible and used at low levels so it does not linger in pores or form an occlusive film that traps oil. The cholesterol portion is balanced by the short PEG chain which keeps the molecule lightweight and easy to rinse away. Because of this, clogged pores and breakouts are unlikely. Acne-prone users can generally consider it safe. If layered with very heavy oils or waxes, overall formula buildup could raise the risk slightly but the ingredient itself remains low on the scale.

Summary

Methoxy Peg-7 Dehydrocholesteryl Succinate serves as an antioxidant, a mild UV filter and a hair conditioning agent. Its antioxidant activity comes from the succinate group that helps mop up free radicals, protecting both the formula and the skin surface. The steroid backbone absorbs a slice of UV light to add a small boost to sun protection, while the cholesterol-like structure lays down a flexible film that smooths hair and softens skin without a greasy afterfeel.

It is not a headline ingredient yet it appears in a steady stream of daily moisturizers, lightweight sunscreens and color-protecting hair products because formulators value its multitasking nature and gentle profile.

Safety data show very low irritation and sensitization potential for most users, including sensitive skin. Still, everyone’s skin chemistry is different; patch testing any new product is a smart step before full-face or full-scalp use.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search