Methylsilanol Glycyrrhizinate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Methylsilanol Glycyrrhizinate?

Methylsilanol Glycyrrhizinate is a skin-care ingredient that links a small silicon-based molecule, called methylsilanol, with glycyrrhizic acid, the soothing substance that comes from licorice root. The result is a stable ester that carries the comforting traits of licorice along with the lightweight feel often seen in silicone chemistry. The idea of joining these two parts took shape in the late 1990s when formulators searched for gentler options to calm skin while improving texture. To make it, chemists first extract glycyrrhizic acid from licorice, convert it to a water-friendly salt, then react it with a methylsilanol derivative under controlled heat and pH until the two pieces bond. After filtering and drying, the powder or liquid can be blended into cosmetic bases. You will most often spot it in serums, sheet masks, anti-aging creams, daily moisturizers and after-sun soothing gels where brands want a soft touch without added weight or oil.

Methylsilanol Glycyrrhizinate’s Cosmetic Benefits/Uses

In formulas this ingredient is valued for one main job that influences how the finished product feels and performs on skin.

As a skin conditioning agent it helps keep the surface smooth, supple and comfortable. Its licorice part brings a mild calming effect that can ease the look of temporary redness while the silanol part supports light hydration. Together they give creams and gels a silky glide, help maintain skin softness throughout the day and can enhance the overall sensory appeal of a product.

Who Can Use Methylsilanol Glycyrrhizinate

Because it is light, non greasy and calming, Methylsilanol Glycyrrhizinate tends to suit all major skin types including oily, combination, normal and dry. Sensitive or redness-prone complexions often tolerate it well since the licorice portion helps soothe visible irritation. It is not known to clog pores or trigger excess oil so acne-prone users can usually apply it without concern. There are no specific reasons it would be unsuitable for mature or teenage skin.

The compound is created from plant-based licorice extract linked to a small silicone derivative and contains no animal-derived substances so it is considered appropriate for vegans and vegetarians.

No research suggests the ingredient is harmful during pregnancy or while breastfeeding when used topically at normal cosmetic levels. Still this is not medical advice and anyone who is pregnant or nursing should have a doctor review any skincare product they plan to use.

Methylsilanol Glycyrrhizinate is not known to cause photosensitivity so it will not make skin more prone to sunburn. Standard daily sunscreen use is still recommended for overall skin health.

Potential Side Effects/Adverse Reactions

Responses to topical Methylsilanol Glycyrrhizinate differ from person to person. The effects listed below are only potential outcomes and, when the ingredient has been formulated properly, most people will not experience any of them.

  • Mild stinging or itching
  • Transient redness at the application site
  • Contact dermatitis in individuals allergic to licorice derivatives
  • Very rare silicone sensitivity presenting as small bumps or dryness

If any of these reactions occur discontinue use and seek advice from a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 0 / 5

Methylsilanol Glycyrrhizinate carries no oily fatty acids, waxes or heavy polymers that can block pores. Its silanol backbone is lightweight and water compatible while the licorice segment is mostly sugar based, so it spreads in a thin film that rinses away easily. Published ingredient databases and supplier data sheets list it as non occlusive and non pore clogging, supporting a zero rating.

Because of this profile the ingredient is generally suitable for people who are prone to acne or breakouts. Of course overall formula design, the presence of other comedogenic substances and individual skin differences will still influence final results.

Summary

Methylsilanol Glycyrrhizinate is used mainly as a skin conditioning agent that calms visible redness, lightly hydrates and leaves a silky after feel. It achieves these effects by pairing the soothing properties of licorice derived glycyrrhizic acid with a small silicone unit that improves spreadability and moisture retention without heaviness.

You will not see it headlining as often as classic actives like niacinamide or hyaluronic acid, yet formulators who want a gentle licorice benefit in a modern light texture do reach for it, so it shows up in niche soothing serums, masks and daily creams.

Current safety data finds it well tolerated, non sensitizing and non comedogenic at the low percentages used in cosmetics. Still every skin is unique; perform a simple patch test the first time you try any product containing this ingredient to ensure personal compatibility.

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