Methyltrimethoxysilane: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Methyltrimethoxysilane?

Methyltrimethoxysilane is an organosilicon compound often shortened to MTMS. Chemically, it is a small molecule made of a single silicon atom bonded to one methyl group and three methoxy groups. In plain terms it sits somewhere between organic and mineral worlds giving it a unique set of properties. MTMS does not occur naturally; it is produced industrially by reacting methylchlorosilanes with methanol then purifying the result. This controlled process yields a clear low-viscosity liquid that blends easily with other cosmetic ingredients.

The cosmetics industry first took interest in MTMS in the late twentieth century when formulators were looking for lightweight alternatives to heavy film formers like certain waxes and gums. Its ability to create a flexible breathable layer on skin or hair made it attractive for modern beauty products. Today you will most often spot Methyltrimethoxysilane in facial primers, long-wear foundations, waterproof mascaras, hair styling sprays and some sheet mask essences where a smooth even finish is essential.

Methyltrimethoxysilane’s Cosmetic Benefits/Uses

In topical products the main role of Methyltrimethoxysilane is straightforward yet valuable.

As a film forming agent it spreads into a thin uniform layer that dries quickly. This invisible film helps makeup adhere longer, boosts water resistance, reduces smudging, controls frizz on hair surfaces and can give skin a silky feel without heaviness. Because the film is permeable it allows moisture and air to pass so skin still feels comfortable.

Who Can Use Methyltrimethoxysilane

Methyltrimethoxysilane is lightweight and non-occlusive so it tends to suit most skin types including oily, combination, normal and even sensitive skin that dislikes heavy textures. Very dry or compromised skin might find it less nourishing on its own since it does not add moisture but relies on other ingredients in the formula to do so.

The compound is made synthetically without any animal-derived materials which makes it acceptable for vegans and vegetarians.

Current safety data shows no known issues for topical use during pregnancy or while breastfeeding. Still this is not medical advice and anyone who is pregnant or nursing should check with a doctor before adding new products to their routine just to be safe.

Methyltrimethoxysilane does not cause photosensitivity so it will not make skin more prone to sunburn. It is also fragrance-free and non-reactive with common active ingredients like vitamin C or retinoids which helps it play nicely in layered routines.

Potential Side Effects/Adverse Reactions

Responses to any cosmetic ingredient can differ from person to person. The effects listed below are possible but unlikely when the product is well formulated and used as directed.

  • Temporary skin dryness
  • Mild irritation in very sensitive skin
  • Eye stinging if product is accidentally rubbed into the eyes

If you notice any of these issues stop using the product and consult a healthcare professional if symptoms persist.

Comedogenic Rating

Rating: 0 / 5

Methyltrimethoxysilane is a very small lightweight silicone derivative that sits on the surface rather than sinking into pores. It dries to a permeable flexible film that does not trap oil or bacteria so it is considered non-comedogenic.

Because of this rating, the ingredient is generally suitable for acne-prone or breakout-prone skin.

Its low viscosity also means formulators can use it at modest levels without needing heavy emulsifiers or oils, further lowering the risk of clogged pores in the finished product.

Summary

Methyltrimethoxysilane acts mainly as a film former, creating an ultrathin layer that helps makeup grip, boosts water resistance, tames frizz, and leaves skin with a smooth lightweight feel. It achieves this by rapidly crosslinking on contact with moisture in the air, forming a breathable mesh that moves with skin or hair instead of cracking.

The ingredient enjoys quiet popularity in long-wear foundations, primers, waterproof mascaras and some hair sprays but it is not as well known to the average consumer because it usually sits low on ingredient lists and does its job invisibly.

Current research and industry use show it to be safe for topical application with very low irritation potential. As with any new product, a quick patch test is a smart way to confirm personal tolerance before full-face or full-scalp application.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search