Microbial Cellulose: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Microbial Cellulose?

Microbial Cellulose is a network of ultra-fine cellulose fibers produced when the bacterium Gluconacetobacter xylinus ferments a sugar rich solution. Chemically it is the same cellulose found in plants yet it forms a much purer and more tightly woven structure because the bacteria spin the fibers one by one. This dense mesh locks in up to 100 times its weight in water, giving it a soft gel-like feel.

The material first showed up in food and biomedical fields in the late 1980s thanks to its high purity and remarkable water retention. As formulators searched for skin-friendly materials that could hold moisture without synthetic polymers, microbial cellulose moved into cosmetics in the early 2000s. Today it is produced in stainless-steel fermenters where the bacteria are fed glucose and minerals. After several days the floating cellulose sheet is harvested, washed to remove any nutrients or bacterial cells, then milled or cut to the desired form.

Its ability to form thin, flexible sheets makes it popular for sheet masks and under-eye patches. In gel form it appears in moisturizers, soothing after-sun products, anti-aging serums and leave-on treatments that aim to deliver a burst of hydration while feeling light on the skin.

Microbial Cellulose’s Cosmetic Benefits/Uses

In skincare formulas microbial cellulose is prized mainly for one technical role that directly improves the user experience.

As a viscosity controlling agent it thickens water-based products, creating a smooth cushiony texture that spreads evenly without dripping. This helps stabilize emulsions, keeps suspended actives from settling and allows sheet masks to cling closely to the face so ingredients stay in contact with the skin longer.

Who Can Use Microbial Cellulose

Because microbial cellulose is inert and non irritating it suits nearly every skin type including dry, oily, combination and sensitive skin. Its water holding mesh delivers hydration without oil so even acne prone complexions usually tolerate it well. People with highly reactive skin should still double check the full product ingredient list, as reactions are more likely to stem from other additives rather than the cellulose itself.

The material is produced by fermenting plant derived sugars with bacteria, not by harvesting from animals, making it acceptable for vegans and vegetarians.

No research indicates that topical microbial cellulose poses a risk for women who are pregnant or breastfeeding. Still, this is not medical advice and anyone expecting or nursing should run all skincare products past a healthcare professional just to be on the safe side.

It does not increase photosensitivity so there is no special need for extra sun precautions beyond a normal daily sunscreen.

Potential Side Effects/Adverse Reactions

Responses to any cosmetic ingredient can vary from person to person. The effects listed below are only potential issues and are unlikely to be the typical user experience, assuming the final formula has been properly manufactured.

  • Allergic contact dermatitis – a small number of users may notice redness, itching or a rash if hypersensitive to cellulose or trace fermentation residues
  • Temporary tight feeling – the film left as the product dries can feel slightly tight on very dry skin until moisturizer is applied
  • Breakouts in extremely acne prone skin – while non comedogenic on its own, very occlusive formulas built around microbial cellulose sheets or gels can sometimes trap sweat and sebum leading to clogged pores in rare cases

If irritation or any other negative reaction develops stop use immediately and consult a qualified healthcare provider.

Comedogenic Rating

Rating: 0 out of 5. Microbial Cellulose is a water-packed polysaccharide that sits on top of the skin then rinses or peels away without sinking into pores, so it does not block oil flow or feed acne bacteria. For most people, even those who break out easily, this makes it a safe pick. The only time clogged pores might appear is when the cellulose sheet is combined with a very heavy cream or left on sweaty skin for long periods, and that effect comes from the overall formula, not the cellulose itself.

Summary

Microbial Cellulose is mainly used to control viscosity and hold water. Its tight fiber web soaks up large amounts of liquid, thickens watery mixes, stabilizes suspended actives and forms flexible films that hug the skin in sheet masks. These traits let formulators create smooth hydrating gels and masks without synthetic gums.

While still less common than plant gums or synthetic polymers, its presence is growing in K-beauty masks, after-sun gels and soothing serums thanks to the clean label appeal of a naturally fermented material.

Safety studies and years of cosmetic use show it is very low risk, with allergies or breakouts being rare. As with any new skincare product, it is wise to do a quick patch test before full use to make sure your skin agrees with the complete formula.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search