Mipa-C12-14 Sec-Pareth-3 Acetate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Mipa-C12-14 Sec-Pareth-3 Acetate?

Mipa-C12-14 Sec-Pareth-3 Acetate is a synthetic compound created when monoisopropanolamine reacts with the acetate ester of a specific group of fatty alcohol ethoxylates known as C12-14 Sec-Pareth-3. The end result is a salt that looks like a clear to slightly hazy liquid and blends easily with water and oils. Its roots trace back to the rise of modern surfactant chemistry in the late twentieth century when formulators sought milder alternatives to traditional soaps. By tweaking fatty alcohol chains and adding ethoxylated segments scientists produced ingredients that clean effectively yet feel gentle on skin. Converting the base surfactant into its acetate salt further improved stability and compatibility in finished products so the ingredient gained steady popularity in personal care labs.

Manufacturing begins with plant-derived or petroleum-based fatty alcohols that are first “sec” (secondary) alcohols. These are ethoxylated with a precise average of three ethylene oxide units forming C12-14 Sec-Pareth-3. The material then undergoes esterification with acetic acid followed by neutralization with monoisopropanolamine to yield the final salt. Each step is controlled to remove unwanted residues ensuring the finished ingredient meets cosmetic grade standards.

You will most often find Mipa-C12-14 Sec-Pareth-3 Acetate in rinse-off products such as facial cleansers, body washes and shampoos where it supports mild yet thorough cleansing. It also appears in bubble baths, micellar waters, makeup removers, exfoliating masks and even some light lotions or creams that need a gentle emulsifier to keep oil and water mixed.

Mipa-C12-14 Sec-Pareth-3 Acetate’s Cosmetic Benefits/Uses

Formulators value this multi-tasking ingredient for several performance roles

  • Cleansing: Lowers surface tension so water can lift away dirt, oil and makeup without stripping natural moisture
  • Emulsifying: Helps blend oily ingredients with water creating stable lotions, creams and cleansers that do not separate on the shelf
  • Foam Boosting: Enhances the volume and creaminess of lather in soaps or shampoos making the wash experience more luxurious
  • Hydrotrope: Improves the solubility of other ingredients in water-rich formulas which can reduce cloudiness and allow for clear gels or liquids

Who Can Use Mipa-C12-14 Sec-Pareth-3 Acetate

This ingredient is generally well tolerated by normal, oily or combination skin because it cleanses effectively yet is considered milder than traditional sulfates. Sensitive skin often does fine with it too, though people experiencing an active flare of eczema or very dry compromised skin might prefer richer cream cleansers with fewer surfactants since any foaming agent can add to moisture loss if overused.

Mipa-C12-14 Sec-Pareth-3 Acetate is synthesized from plant or petroleum sourced materials and contains no animal derivatives, so it is suitable for both vegetarians and vegans as long as the finished product is certified cruelty free.

The compound has no known reproductive toxicity and is not on restriction lists for pregnancy or nursing. That said this is not medical advice and anyone who is pregnant or breastfeeding should review any skincare routine with a qualified healthcare professional to be on the safe side.

The ingredient does not increase photosensitivity, so it will not make skin more prone to sunburn. Standard daily sun protection is still recommended for overall skin health.

Potential Side Effects/Adverse Reactions

Responses to topical Mipa-C12-14 Sec-Pareth-3 Acetate can vary from person to person. The following list covers potential side effects yet these outcomes are uncommon when the ingredient is used at typical cosmetic levels in a properly formulated product.

  • Temporary skin dryness or tightness, especially if the cleanser is left on too long or used excessively
  • Mild to moderate irritation such as redness or itching in very sensitive individuals
  • Eye stinging or watering if the product accidentally gets into the eyes
  • Allergic contact dermatitis in rare cases where a person develops specific sensitivity to the ingredient
  • Exacerbation of pre existing skin conditions if applied to broken or severely compromised skin

If any irritation or discomfort occurs, discontinue use and consult a healthcare professional for guidance.

Comedogenic Rating

Rating: 1 / 5

Mipa-C12-14 Sec-Pareth-3 Acetate is a water-soluble surfactant that rinses off cleanly and does not leave a heavy oily film on skin or hair. Because it is used at modest levels and has a light, non-occlusive texture, it is very unlikely to clog pores. For that reason formulators generally view it as having a low comedogenic potential.

In most cases this ingredient is suitable for people who are prone to acne or breakouts.

If paired with thick oils or butters in a formula, overall pore-clogging risk depends more on those richer ingredients than on Mipa-C12-14 Sec-Pareth-3 Acetate itself.

Summary

Mipa-C12-14 Sec-Pareth-3 Acetate works as a gentle cleanser, foam booster, emulsifier and hydrotrope. It lowers surface tension so water can lift away dirt and oil, builds a creamy lather that feels pleasant, helps oil and water stay mixed in lotions or washes and keeps other ingredients dissolved for clear, stable formulas.

While not a buzzword ingredient you will see splashed across marketing ads, it sits quietly in many everyday cleansers, shampoos and micellar waters because it performs well and is easy to work with.

Safety data show a low irritation profile when used at normal cosmetic levels. Still, individual skin can react in unexpected ways so it is smart to do a quick patch test when trying any new product that contains this ingredient.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search