Mixed Isopropanolamines Myristate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Mixed Isopropanolamines Myristate?

Mixed Isopropanolamines Myristate is created when myristic acid, a fatty acid commonly sourced from coconut or palm kernel oil, is neutralized with a blend of isopropanolamine compounds. The reaction forms amine salts that have both a fatty portion from myristic acid and a water-friendly amine portion. This dual nature makes the ingredient suited for removing dirt and oil from skin and hair.

Amine salts began gaining popularity in personal care during the mid-20th century as formulators searched for gentler alternatives to harsh soaps. Over time, combining fatty acids with isopropanolamines proved particularly effective, leading to ingredients like Mixed Isopropanolamines Myristate finding a place in modern cosmetics.

Production starts with refining natural oils to isolate myristic acid. The acid is then carefully combined with mixed isopropanolamines under controlled heat and pH conditions until the desired salt forms. The result is a stable, surfactant-rich ingredient that can be added straight into water-based or emulsion formulas.

You will most often see Mixed Isopropanolamines Myristate in facial cleansers, body washes, shampoo, micellar waters, makeup removers and occasionally in rinse-off masks or exfoliating scrubs where extra cleansing power is needed without stripping skin.

Mixed Isopropanolamines Myristate’s Cosmetic Benefits/Uses

This ingredient contributes mainly as a cleansing agent within personal care formulas.

  • Cleansing: Its surfactant properties allow it to loosen and lift away excess sebum, makeup and daily grime, helping products foam or emulsify oils so they rinse off easily. This leads to a fresh, clean feeling without leaving a heavy residue, which supports balanced skin and hair

Who Can Use Mixed Isopropanolamines Myristate

Because this ingredient is primarily a cleansing surfactant that is rinsed off, it is generally suitable for most skin types, including normal, oily and combination skin. Dry or sensitive skin can usually tolerate it in well-formulated products, especially when paired with soothing or hydrating ingredients, but those skin types may prefer lower concentrations to avoid a tight feel after cleansing.

Mixed Isopropanolamines Myristate is plant derived since the myristic acid typically comes from coconut or palm oils and the isopropanolamines are synthesized without animal by-products. That makes it acceptable for vegans and vegetarians, provided the overall product is also cruelty free.

No specific restrictions have been issued for pregnant or breastfeeding individuals when it comes to topical use of this ingredient. It has a large molecular size, minimal skin penetration and is rinsed away, so systemic exposure is expected to be very low. This is not medical advice and pregnant or nursing users should still check with their healthcare provider before starting any new skincare product to be safe.

The ingredient does not increase photosensitivity, so it will not make skin more prone to sunburn. As with any cleanser, follow with a broad-spectrum sunscreen during the day to protect freshly cleansed skin.

Potential Side Effects/Adverse Reactions

Responses to topical Mixed Isopropanolamines Myristate differ from person to person. The following is a list of potential side effects that could occur, though most users will not experience them when the ingredient is formulated correctly and used as directed.

  • Transient stinging or redness on very sensitive or compromised skin
  • Dryness or tightness if used in high concentrations or without sufficient moisturizing agents in the formula
  • Mild eye irritation if cleanser is accidentally rubbed into the eyes
  • Allergic contact dermatitis in rare cases for individuals sensitized to amine-based surfactants
  • Increased irritation when layered with other potent exfoliants or harsh surfactants in the same routine

If you notice persistent irritation, discontinue use and consult a medical professional for guidance.

Comedogenic Rating

Rating: 1 out of 5. Mixed Isopropanolamines Myristate is highly water soluble and designed to be rinsed off, so it does not linger on skin long enough to block pores. Its molecular structure favors lifting oil rather than acting like an oil, which keeps pore clogging risk low.

Most acne-prone users should find it compatible with their routines.

Any pore issues are more likely to stem from heavier emollients in the same formula, not from this cleansing agent itself.

Summary

Mixed Isopropanolamines Myristate functions mainly as a cleansing surfactant. The fatty tail from myristic acid grabs onto oils and debris while the amine salt head mixes with water, allowing grime to wash away without harsh stripping. This dual action makes it a helpful supporting player in face washes, shampoos and micellar waters.

It is moderately common in rinse-off products but not a buzzworthy star ingredient, partly because consumers focus on more recognizable actives while formulators quietly rely on it for gentle yet effective cleansing.

Overall safety is high: it is plant derived, rinse-off and has a low irritation record when used at typical levels. As with any new skincare product though it is smart to patch test first to rule out individual sensitivities.

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