Morpholine Oleate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Morpholine Oleate?

Morpholine oleate is the result of pairing oleic acid, a fatty acid naturally abundant in plant oils like olive or sunflower, with morpholine, a simple nitrogen-containing ring compound. When the two react in a 1:1 ratio they create a salt that is water-compatible yet still carries the oily character of oleic acid. First explored in the mid-20th century as a surfactant for industrial cleaners, it eventually caught the attention of cosmetic chemists looking for gentle alternatives to harsher soaps. Today manufacturers typically produce morpholine oleate by neutralizing purified oleic acid with morpholine under controlled temperatures, then filtering and concentrating the mixture to a stable liquid or paste. Because of its surface-active properties it is most often blended into facial cleansers, micellar waters, body washes, exfoliating masks and occasionally lightweight shampoo formulas where mildness and rinse-off ease are priorities.

Morpholine Oleate’s Cosmetic Benefits/Uses

In personal care formulas morpholine oleate serves one key role that supports clean, comfortable skin and hair:

Cleansing: Acting as a surfactant it loosens makeup, excess oil and daily grime so they can be rinsed away with water. Its fatty acid backbone gives it a softer touch than sulfate detergents helping products foam moderately without over-stripping natural moisture.

Who Can Use Morpholine Oleate

Morpholine oleate is generally well tolerated by most skin types including oily, combination, normal and many sensitive skins thanks to its mild surfactant profile. Those with very dry or compromised skin barriers might feel a bit of tightness if the formula is left on too long or used too often so pairing with a hydrating moisturizer is smart.

The ingredient is suitable for vegans and vegetarians because oleic acid is typically harvested from plant oils like olive or sunflower rather than animal fats and morpholine is a synthetic compound.

No specific warnings exist for pregnant or breastfeeding users since morpholine oleate stays largely on the skin surface and is rinsed away, still this is not medical advice and anyone expecting or nursing should run all skincare choices past a trusted doctor just to be safe.

Morpholine oleate does not make skin more sensitive to sunlight, so it is not considered photosensitizing. It also plays well with most other common skincare actives though very strong acids or solvents in the same formula could raise the chance of dryness.

Potential Side Effects/Adverse Reactions

Side effects and reactions to topical morpholine oleate differ from person to person. The following list covers potential issues yet most users will not experience them when the ingredient is used correctly in a finished product.

  • Transient redness or mild stinging on sensitive skin, especially if the product sits for several minutes before rinsing
  • Eye irritation if cleanser accidentally gets into the eyes
  • Dryness or tight feel on very dry or eczema-prone skin after frequent use
  • Rare allergic contact dermatitis in individuals sensitive to morpholine or fatty acid salts
  • Increased irritation if combined with high levels of exfoliating acids or alcohol in the same formula

If any of these reactions occur stop using the product and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 2 / 5

Morpholine oleate carries a small risk of clogging pores because oleic acid on its own can be mildly comedogenic, yet that risk is lowered once the fatty acid is converted to a water-soluble salt and used in rinse-off cleansers. In most finished formulas it is present at modest levels and is washed away within seconds, making it far less likely to linger inside pores.

With its rating of 2 most people prone to acne can use products containing morpholine oleate without trouble, especially if the cleanser is fully rinsed off.

Extra context: the overall comedogenicity of a product will also depend on the other oils, waxes or thickeners in the formula, so always look at the ingredient list as a whole.

Summary

Morpholine oleate serves mainly as a mild cleanser that lifts makeup, sebum and dirt so they rinse away easily. It achieves this by combining the oil-attracting tail of oleic acid with the water-loving head of morpholine, allowing it to bridge oil and water during washing.

While helpful, this ingredient is not a household name and is used less often than bigger surfactant stars like cocamidopropyl betaine or sodium cocoyl isethionate. You will mostly find it in niche or sensitive-skin cleansers where formulators want gentle performance without heavy foaming.

Overall safety is considered high when morpholine oleate is used at the low levels typical for rinse-off products. Side effects are uncommon and generally mild. As with any new skincare step it is wise to patch test to make sure your own skin stays happy.

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