Myricitrin: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Myricitrin?

Myricitrin is a plant derived flavonoid glycoside most commonly extracted from the bark and leaves of bayberry, sweet gale and several other Myrica species. Chemically, it combines the antioxidant flavonol myricetin with a rhamnose sugar, creating a water soluble molecule that is easy to incorporate into cosmetic formulas. Traditional herbal preparations featuring bayberry date back centuries for their soothing and toning properties; once researchers isolated myricitrin in the 19th century its strong antioxidant activity quickly drew scientific interest. Modern cosmetic use began in the early 2000s when advances in gentle solvent extraction and chromatographic purification made it possible to obtain high purity myricitrin on a commercial scale. Today manufacturers typically source the raw plant material, perform an ethanol water extraction, concentrate the extract then isolate myricitrin through column filtration and spray drying, resulting in a fine, light yellow powder. Because it dissolves in both water and alcohol based systems it appears in serums, anti-aging creams, protective day moisturizers, sheet masks, after-sun gels and other treatments aimed at shielding skin from environmental stressors.

Myricitrin’s Cosmetic Benefits/Uses

Formulators prize myricitrin for two key performance roles that help keep skin looking healthy and resilient.

  • Antioxidant – Neutralizes free radicals generated by UV light, pollution and normal metabolic processes, helping prevent the oxidative damage that can lead to dull tone, fine lines and premature aging
  • Skin protecting – Supports the skin’s natural barrier by reducing oxidative stress and calming the cascade of irritation linked to environmental aggressors, which in turn promotes a smoother, more comfortable complexion
Who Can Use Myricitrin

Because myricitrin is water soluble and non-oily it suits most skin types including oily, combination, normal and dry. Sensitive skin generally tolerates it well thanks to its calming antioxidant profile, although people with very reactive skin should still proceed cautiously when trying any new formula. It is not known to clog pores so acne-prone users can usually benefit from its protective effects without added breakouts.

The ingredient is plant derived and typically processed without animal by-products which makes it appropriate for both vegetarians and vegans. Formulators often highlight it in cruelty-free lines for this reason.

No specific data links topical myricitrin to problems during pregnancy or breastfeeding. Current research suggests it stays on the surface layers of skin and is unlikely to reach the bloodstream in meaningful amounts. That said this is not medical advice and anyone who is pregnant or nursing should review any skin care product with their doctor first to be safe.

Myricitrin does not increase photosensitivity so daytime use is generally fine, though pairing it with a broad-spectrum sunscreen is still smart skin care. It layers comfortably with most common actives such as niacinamide and hyaluronic acid and can even boost the stability of vitamin C, making it a versatile addition to multi-step routines.

Potential Side Effects/Adverse Reactions

Reactions to topical myricitrin differ from person to person. The points below outline potential side effects that could occur, but for the vast majority of users who apply a well-formulated product none of these issues are expected.

  • Mild redness or warmth
  • Stinging sensation on very sensitive or compromised skin
  • Dry patches if combined with high levels of alcohol in the formula
  • Allergic contact dermatitis in individuals allergic to bayberry or related plants
  • Interaction with potent exfoliating acids leading to temporary irritation

If any of these effects appear discontinue use and seek advice from a qualified healthcare professional.

Comedogenic Rating

Rating: 0/5 – Myricitrin is a lightweight water soluble flavonoid with no oily or waxy constituents, so it does not occlude pores or feed acne-causing bacteria. This makes it well suited for people who are prone to breakouts. Because it is usually added at low concentrations and does not alter sebum composition, the risk of congestion is considered negligible. If a formula containing myricitrin triggers blemishes, it is almost always due to other ingredients in the product rather than the flavonoid itself.

Summary

Myricitrin delivers antioxidant and skin protecting benefits by scavenging free radicals, calming irritation linked to pollution and UV exposure and supporting the skin’s natural barrier. Although it has been studied since the 19th century its use in cosmetics remains relatively niche compared with headline ingredients like vitamin C or retinol, yet interest is growing in plant driven protective actives, so it is starting to appear in more serums and day creams.

Current data shows topical myricitrin is well tolerated across skin types with a very low risk of adverse effects, making it a safe choice for daily use. Still, everyone’s skin is unique so patch testing any new product that includes myricitrin is a smart step before adding it to a full routine.

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