What Is Myristalkonium Saccharinate?
Myristalkonium Saccharinate is a quaternary ammonium compound paired with saccharinate, a salt form of saccharin. Chemically it is known as benzyldimethyl(tetradecyl)ammonium combined in a one-to-one ratio with 1,2-benzisothiazol-3(2H)-one 1,1-dioxide. The quaternary ammonium part carries a positive charge that helps it latch onto microbial cell walls, while the saccharinate portion balances the charge and improves the ingredient’s overall stability and solubility in water-based formulas.
The roots of this ingredient trace back to the mid-20th century when quaternary ammonium compounds were first explored for their germ-killing abilities in household cleaners. Formulators later recognized that pairing the quat with a milder counter-ion like saccharinate created a gentler option suitable for leave-on skin and hair products. By the 1990s it began appearing in cosmetic labs as an alternative to traditional parabens and formaldehyde donors.
Manufacturing starts with tetradecyl dimethylamine, which is reacted with benzyl chloride to form benzyldimethyl(tetradecyl)ammonium chloride. The chloride ion is then swapped out through an ion-exchange step that introduces saccharinate, yielding a white to off-white powder that dissolves quickly in water or alcohol.
You will typically find Myristalkonium Saccharinate in water-rich products where microbial growth is a concern. These include facial cleansers, sheet masks, hydrating lotions, lightweight gels, hair conditioners, makeup removers and single-use wipes.
Myristalkonium Saccharinate’s Cosmetic Benefits/Uses
Formulators choose Myristalkonium Saccharinate mainly for its ability to keep products fresh and safe during their shelf life.
As a preservative it controls the growth of bacteria, yeast and mold in water-based cosmetics. This protection helps prevent spoilage, color changes or bad odors and reduces the risk of skin irritation that can come from contaminated products. Because it is effective at low concentrations it allows brands to maintain a pleasant feel and scent without loading the formula with heavy preservatives.
Who Can Use Myristalkonium Saccharinate
This preservative is generally considered non-comedogenic and light enough for all skin types including oily, combination, normal and even dry skin that needs protection against microbial growth. Highly sensitive or compromised skin may prefer minimalist formulas but most people tolerate the ingredient well at the low levels used in cosmetics.
Myristalkonium Saccharinate is made from fully synthetic starting materials so it contains no animal derived substances. This makes it suitable for both vegans and vegetarians.
There is no specific evidence suggesting that pregnancy or breastfeeding creates unique risks with topical exposure to this preservative. Nevertheless this is not medical advice and anyone who is pregnant or nursing should review all personal care products with a qualified healthcare provider to be safe.
The ingredient does not increase photosensitivity so there is no special need for added sun protection beyond your usual routine.
Potential Side Effects/Adverse Reactions
Side effects from topical use of Myristalkonium Saccharinate vary by individual. The points below list potential reactions yet most users will not encounter them when the ingredient is properly dosed in a well formulated product.
- Mild skin irritation such as redness itching or stinging
- Contact dermatitis in people who are allergic to quaternary ammonium compounds
- Eye irritation if the product is rubbed into the eyes
- Dryness or tightness when used in very high concentrations
If you experience any of the effects mentioned stop using the product and consult a healthcare professional.
Comedogenic Rating
Rating: 0
Myristalkonium Saccharinate is water soluble and used at very low levels, so it does not leave an oily or occlusive film on the skin that could trap debris in pores. Its quaternary ammonium structure rinses cleanly and stays suspended in the water phase of a formula rather than sitting on the skin’s surface. As a result it is considered non-comedogenic.
Suitable for acne-prone or breakout-prone skin.
Because it is a preservative rather than an emollient or thickening agent, even higher concentrations do not raise clogging concerns but those levels might cause irritation instead.
Summary
Myristalkonium Saccharinate mainly acts as a preservative that controls bacteria, yeast and mold in water-based cosmetics. The positively charged ammonium group binds to microbial cell membranes while the saccharinate counter-ion keeps the ingredient stable and easy to dissolve, letting it protect formulas without affecting feel or scent.
It is not a household name like parabens or phenoxyethanol, so its use is still niche, often seen in indie or specialty brands looking for alternative preservative systems.
Current data and real-world use show it to be safe for most skin types when used at the low percentages allowed in cosmetics. Still, skin can react unpredictably so it is wise to patch test any new product that lists Myristalkonium Saccharinate just to be sure your skin stays comfortable.