Myristamidopropyl Betaine: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Myristamidopropyl Betaine?

Myristamidopropyl Betaine is a mild, coconut-derived cleanser whose full chemical name is (Carboxymethyl)dimethyl-3-[(1-oxotetradecyl)amino]propylammonium hydroxide. It is made by reacting myristic acid, a fatty acid found in coconut and palm kernels, with a gentle amine compound then combining the result with betaine, a naturally occurring molecule in sugar beets. The finished ingredient is water-soluble, has a slight yellow tint and is known for producing a rich yet soft lather.

The cosmetic world began turning to betaine-based surfactants in the 1980s as consumers looked for cleansers that felt softer on skin and hair than traditional soaps. Formulators found that swapping harsher sulfates for amphoteric ingredients like Myristamidopropyl Betaine reduced dryness and irritation while still giving the bubbly experience users expected.

Production starts with plant-sourced myristic acid which is converted to myristamide, linked to propylamine, then reacted with monochloroacetic acid to form the betaine group. Careful control of pH and temperature keeps the molecule stable and ensures low levels of by-products.

Today you will spot Myristamidopropyl Betaine in shampoos, body washes, facial cleansers, baby wash, micellar waters, foam boosters in bubble baths, makeup removers, gentle exfoliating scrubs and even sheet mask essences where a mild cleansing action is needed to lift excess oil without stripping skin.

Myristamidopropyl Betaine’s Cosmetic Benefits/Uses

Formulators add this ingredient for several helpful reasons

  • Antistatic: Helps reduce static charges on hair making it easier to comb and style while cutting down on flyaways
  • Cleansing: Lifts dirt oil and product buildup from skin and hair without the tight squeaky feeling stronger surfactants can leave behind
  • Hair Conditioning: Deposits a light conditioning film that smooths the hair cuticle improving softness and shine
  • Skin Conditioning: Leaves a silky after-feel on skin supporting moisture balance and enhancing overall comfort
  • Foam Boosting: Builds a dense creamy foam that improves the sensory experience and helps spread the product evenly

Who Can Use Myristamidopropyl Betaine

This ingredient is considered gentle enough for all skin types including dry, oily, combination and sensitive skin. Its mild nature means it cleans without pulling away the skin’s natural moisture, so even easily irritated complexions generally tolerate it well. There are no specific skin types that must avoid it unless an individual has a proven allergy to betaine surfactants.

Myristamidopropyl Betaine is typically plant derived because the starting fatty acid is taken from coconut or palm kernels and the betaine portion comes from sugar beets. As long as the finished formula is not mixed with animal by-products, products containing this ingredient suit both vegans and vegetarians.

No research points to risks for pregnant or breastfeeding women when the ingredient is used in rinse-off or leave-on cosmetics at normal levels. This is not medical advice and anyone who is pregnant or nursing should show the full ingredient list of any product to a health professional for personal guidance.

The molecule is not known to raise photosensitivity. Users do not need to change their sun protection habits because of this ingredient. Because it rinses cleanly it also plays well with most other common skincare actives.

Potential Side Effects/Adverse Reactions

Reactions to topical Myristamidopropyl Betaine vary from person to person. The points below list potential side effects that could occur, though they are uncommon when the ingredient is used at the levels normally found in cosmetics.

  • Mild skin redness or stinging in very sensitive users
  • Temporary eye irritation if the product accidentally gets into the eyes
  • Allergic contact dermatitis in individuals specifically allergic to betaine type surfactants
  • Scalp dryness or itch when used in high concentrations or left on for extended periods

If any discomfort or irritation develops stop using the product and seek advice from a qualified healthcare professional.

Comedogenic Rating

Rating: 1 / 5. Myristamidopropyl Betaine is water-soluble and rinses clean, so it does not sit on skin long enough to clog pores. It contains a fatty acid tail, yet the molecule is highly surface active which keeps it from building up inside pores. Because most products with this ingredient are wash-off, residue left behind is minimal.

Suitable for acne-prone skin thanks to its very low likelihood of causing breakouts.

Formulas that leave the ingredient on skin for long periods or combine it with heavy oils may raise the risk slightly, but in standard cleansers the chance of congestion is close to zero.

Summary

Myristamidopropyl Betaine acts as a gentle cleanser, antistatic agent, mild hair and skin conditioner and foam booster. Its amphoteric structure lets one end cling to oil and grime while the other bonds with water, lifting away dirt without stripping natural moisture. The molecule’s positive charge helps smooth hair cuticles and reduce static, leaving strands softer and shinier, and it creates a creamy foam that feels lush during use.

The ingredient is popular in shampoos, face washes, body washes and baby products because consumers want mild cleansers that still lather well. While it is not as famous as sulfates or coco-glucoside, formulators reach for it often when they need extra softness in a formula.

Overall safety reports are reassuring and irritation rates are low, making it a friend to most skin types including sensitive and acne-prone. As with any new product, do a quick patch test to make sure your skin agrees with the full formula.

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