Myristamidopropyl Hydroxysultaine: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Myristamidopropyl Hydroxysultaine?

Myristamidopropyl Hydroxysultaine is a mild, coconut or palm derived surfactant created by combining myristic acid with a propylamine then reacting the result with sultone to form the hydroxysultaine group. Chemically it is classed as an amphoteric compound, meaning it can carry either a positive or negative charge depending on the surrounding pH. The ingredient first gained popularity in the early 1990s when formulators were looking for gentler alternatives to traditional sulfates that could still deliver rich foam. Since then it has become a staple in rinse off personal care because it balances cleansing power with skin friendliness. You will often spot it in shampoos, body washes, facial cleansers, baby baths, bubble baths, micellar waters, shaving creams, hand soaps, hair conditioners and even some sheet mask serums where a light cleanser is needed to remove excess oils.

Myristamidopropyl Hydroxysultaine’s Cosmetic Benefits/Uses

Formulators value this multitasker for several reasons

  • Antistatic – helps reduce static charge on hair strands which means less fly-away and smoother styling
  • Cleansing – lifts dirt, oil and product buildup without stripping skin or hair making daily washes feel gentle yet effective
  • Hair Conditioning – leaves a soft feel and improves combability so hair feels conditioned right out of the shower
  • Skin Conditioning – deposits a light conditioning film that prevents tightness after washing keeping skin comfortable
  • Foam Boosting – increases both the volume and stability of lather giving consumers the rich bubbles they associate with cleanliness
  • Viscosity Controlling – helps thicken formulas so gels or washes reach that ideal, luxurious texture without extra thickeners

Who Can Use Myristamidopropyl Hydroxysultaine

This surfactant is generally considered suitable for all skin types including dry, oily, combination and sensitive because it cleans without aggressive stripping. People with very reactive or eczema-prone skin may still prefer shorter contact times or lower concentrations as a precaution since any surfactant can be irritating if left on too long.

Most commercial grades are sourced from coconut or palm so the molecule contains no animal-derived components. As long as the overall formula is free from animal by-products it meets vegan and vegetarian preferences.

Current safety data shows no specific reproductive toxicity. Pregnant or breastfeeding individuals can typically use products containing Myristamidopropyl Hydroxysultaine but this is not medical advice and they should confirm suitability with their healthcare provider.

The ingredient does not make skin more sensitive to sunlight so no extra sun protection measures are needed beyond normal daytime SPF use.

Potential Side Effects/Adverse Reactions

Reactions to topical Myristamidopropyl Hydroxysultaine differ from person to person. The points below outline possible but uncommon effects when the ingredient is used at normal cosmetic levels

  • Mild skin redness or stinging, especially on compromised or very dry skin
  • Allergic contact dermatitis in individuals sensitized to the molecule
  • Eye irritation if the product accidentally gets into the eyes before rinsing
  • Scalp or skin dryness when used in high concentrations or with very frequent washing
  • Incompatibility with very strong anionic surfactants leading to reduced mildness of the final formula

If any discomfort or rash appears stop using the product and consult a qualified healthcare professional

Comedogenic Rating

Rating: 0–1 (essentially non-comedogenic)

Myristamidopropyl Hydroxysultaine is a highly water-soluble cleansing agent that rinses away completely rather than lingering on skin or mixing with skin oils that could block pores. It has a lightweight molecular structure, does not leave an oily film and is used at low levels in rinse-off products, all of which reduce the likelihood of clogging pores. Because of that, it is generally suitable for people who are prone to acne or breakouts.

In very rich leave-on formulas combined with heavy occlusives there is a theoretical chance of buildup, but this scenario is uncommon given the ingredient’s primary use in shampoos and washes.

Summary

Myristamidopropyl Hydroxysultaine works as a gentle multitasking surfactant that cleanses skin and hair, boosts foam, reduces static, lightly conditions and helps thicken formulas. It performs these jobs by carrying both positive and negative charges depending on pH, which lets it bond to dirt for easy rinsing while also depositing a thin conditioning layer that leaves hair soft and manageable without stripping.

Its popularity has grown steadily since the 1990s as consumers and formulators look for sulfate-free options that still feel luxurious. You will spot it in everything from baby washes and micellar waters to high-end shampoos, showing its versatility across price points.

Current safety reviews find it low risk with minimal irritation potential at the levels used in cosmetics. Still, skin can be unpredictable so it is smart to patch test any new product that contains this or any other surfactant, especially if your skin is highly reactive.

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