Myristoyl Pentapeptide-7: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Myristoyl Pentapeptide-7?

Myristoyl Pentapeptide-7 is a lab crafted molecule formed by attaching myristic acid, a fatty acid found in nut oils and dairy fat, to a chain of five amino acids known as Pentapeptide-7. The fatty acid part helps the peptide slip through the skin’s outer layer while the peptide segment is designed to signal the skin to look and feel smoother. Peptide technology started gaining attention in the early 2000s when researchers discovered short chains of amino acids could prompt the skin to behave as if it were younger. Chemists soon linked these peptides with fatty acids to boost penetration and stability, leading to ingredients like Myristoyl Pentapeptide-7 appearing in prestige serums and creams.

Manufacturing begins with fermenting or synthesizing individual amino acids, which are then joined in a precise order to create Pentapeptide-7. This peptide is reacted with myristic acid under controlled conditions to form a stable bond. After purification and quality checks the finished ingredient is delivered as a clear to slightly hazy liquid that blends easily into water based or emulsified formulas.

You will most often see Myristoyl Pentapeptide-7 in anti aging serums, firming eye creams, moisturizing lotions, overnight masks and targeted treatment ampoules where brands want a lightweight ingredient that supports smoother looking skin over time.

Myristoyl Pentapeptide-7’s Cosmetic Benefits/Uses

Formulators choose this peptide for its ability to improve the feel and appearance of skin in several ways.

Skin conditioning: Myristoyl Pentapeptide-7 helps the skin feel softer, look more supple and maintain a healthier moisture balance by signaling surface cells to renew themselves more efficiently and by supporting the skin’s natural barrier function.

Who Can Use Myristoyl Pentapeptide-7

In general this peptide suits most skin types including dry, normal, combination and oily skin because it is lightweight and non greasy. Sensitive skin usually tolerates it as well since it has no added fragrance or harsh exfoliating action, though extremely reactive skin should still proceed with caution. It is considered non pore clogging so acne prone users can typically incorporate it without worsening breakouts.

Myristoyl Pentapeptide-7 is produced through laboratory synthesis using plant derived or bio identical amino acids and fatty acids so it is suitable for vegans and vegetarians. No animal by products are involved in its standard manufacturing process.

Available safety data shows no specific risks for pregnant or breastfeeding women when the ingredient is used in topical skincare at customary levels. This does not constitute medical advice and anyone who is pregnant or nursing should consult a qualified healthcare provider before adding new products.

The molecule does not increase photosensitivity so it can be used day or night without making skin more vulnerable to sunburn. It also layers well with common actives like niacinamide, hyaluronic acid and non exfoliating antioxidants, making it easy to slot into most routines.

Potential Side Effects/Adverse Reactions

Reactions to topical Myristoyl Pentapeptide-7 differ from person to person. The following list covers potential side effects, yet most users will not encounter them when the ingredient is formulated and used correctly.

Temporary redness or flushing

Mild itching or tingling at the point of application

Localized dryness if used with multiple astringent products

Rare allergic contact dermatitis leading to swelling or rash

If any of these effects occur discontinue use and seek medical advice if symptoms persist or worsen.

Comedogenic Rating

Rating: 1 / 5

While myristic acid on its own can clog pores, only one molecule of it is attached to a small peptide in Myristoyl Pentapeptide-7 and the ingredient is used at very low levels in finished formulas. The peptide is water friendly, leaves little oily residue and does not sit inside pores, so the overall clogging risk is minimal.

Suitable for people who are prone to acne or breakouts.

The final product texture and the rest of the formula matter more to pore blockage than this peptide itself, so always look at the whole ingredient list when choosing a product.

Summary

Myristoyl Pentapeptide-7 is a skin-conditioning peptide that helps skin feel softer, look smoother and hold moisture better by nudging surface cells to renew and by supporting the barrier. Brands like it for lightweight anti-aging serums and eye creams, though it has not become as famous as peptides like acetyl hexapeptide-8 or palmitoyl tripeptide-1.

Current research and use levels show it is safe for most skin types with only rare irritation reports. As with any new skincare ingredient it is smart to patch test first so you can be sure your skin agrees with it.

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