What Is Myristoyl Succinoyl Atelocollagen?
Myristoyl Succinoyl Atelocollagen is a modified form of collagen, the well-known protein that gives skin its structure and bounce. In this ingredient the collagen has been treated first with myristoyl chloride, which adds a 14-carbon fatty chain, and then with succinic anhydride, which introduces small acidic groups. Together these changes make the protein more compatible with skin care formulas and easier for the skin’s surface to recognize. The collagen used is usually sourced from fish or bovine hide, then purified to remove the parts that can trigger irritation, a process that turns it into atelocollagen.
The idea of blending collagen with fatty acids took hold in the late 1990s as chemists looked for ways to improve moisture retention in anti-aging products. Adding succinic groups came a little later and helped the ingredient dissolve in water-based and oil-based systems. Today it is made in a series of controlled steps: purified atelocollagen is reacted with myristoyl chloride, washed, then reacted with succinic anhydride. The end product is filtered, dried and milled into a fine powder that easily disperses in creams and serums.
You will most often see Myristoyl Succinoyl Atelocollagen in anti-aging moisturizers, firming serums, sheet masks, eye creams and some leave-on treatments that promise smoother or plumper skin.
Myristoyl Succinoyl Atelocollagen’s Cosmetic Benefits/Uses
This ingredient is classed as a skin-conditioning agent, which means it helps the surface of the skin look and feel better. In practice it forms a lightweight film that traps moisture, softens rough patches and adds a subtle, instant plumping effect. Over time its presence can support a smoother texture and a more supple appearance, making it a popular pick for products aimed at fine lines and dryness.
Who Can Use Myristoyl Succinoyl Atelocollagen
This collagen derivative is generally well tolerated by most skin types, including dry, normal, combination and mature skin. Its lightweight film helps lock in water without leaving a greasy feel, which means oily and acne-prone users often do fine with it as well. Those with very sensitive or highly reactive skin should still keep an eye on how their skin responds since any protein-based ingredient can, in rare cases, set off irritation.
The collagen in this ingredient is usually sourced from fish or bovine hide, so it is not suitable for vegans and may be unacceptable for strict vegetarians. Brands sometimes disclose the animal source on the label or in their FAQs, and a few companies offer plant-based alternatives that provide similar benefits without animal input.
There is no known risk linked to topical use during pregnancy or while breastfeeding, but comprehensive studies are lacking. This information is not medical advice and anyone who is pregnant or nursing should clear new skincare products with their healthcare provider.
Myristoyl Succinoyl Atelocollagen does not make skin more sensitive to sunlight, so it is not considered photosensitising. Routine daytime sunscreen use is still advised for overall skin health.
Potential Side Effects/Adverse Reactions
Responses to topical Myristoyl Succinoyl Atelocollagen differ from person to person. The effects listed below are possibilities, not the norm, and most users experience none of them when the ingredient is properly formulated in a product.
- Mild redness or stinging, especially on very sensitive skin
- Rare allergic reaction for those with collagen or fish/bovine protein allergies
- Breakouts or clogged pores in individuals who react poorly to rich creams containing the ingredient
If any of these effects occur stop using the product and consult a healthcare professional if symptoms persist or worsen.
Comedogenic Rating
Rating: 1 out of 5. Myristoyl Succinoyl Atelocollagen is a large, water-friendly protein that sits lightly on the skin and is unlikely to block pores. The added myristoyl chain is short enough that it does not behave like a heavy oil, though very rich creams that use this ingredient alongside thick butters could raise the pore-clogging potential of the finished product.
Most people who struggle with acne or frequent breakouts can usually use products containing this ingredient without extra concern.
Keep in mind that the overall formulation, not just a single ingredient, decides whether a product will clog pores. Gel or lotion textures are the safest bet if you are worried about comedogenicity.
Summary
Myristoyl Succinoyl Atelocollagen is mainly prized for its skin-conditioning talent. By binding water and forming a soft, flexible film, it boosts surface hydration, smooths rough patches and gives skin a quick, gentle plump. These effects make it a quiet workhorse in anti-aging moisturizers, firming serums and sheet masks, though it has not reached the household-name status of hyaluronic acid or peptides.
Topical use is considered low risk for most skin types with only rare reports of irritation or allergy, mainly in people sensitive to animal-derived proteins. As with any new product it is smart to patch test first to make sure your skin agrees with it.