Myristyl 3-Glyceryl Ascorbate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Myristyl 3-Glyceryl Ascorbate?

Myristyl 3-Glyceryl Ascorbate is a modern form of vitamin C that has been joined with myristyl alcohol, a fatty substance from plant oils, and glycerin, a moisture-loving compound often taken from vegetable sources. By linking these pieces together chemists create a stable, oil-friendly version of vitamin C that can slip easily into creams and lotions without breaking down too quickly. The ingredient first appeared in Japanese skin care labs in the early 2000s when researchers were looking for a gentler vitamin C that would last longer on the shelf and feel silkier on the skin.

Making it starts with natural ascorbic acid (vitamin C). Through a controlled reaction it is bonded to glycerin, then to myristyl alcohol, forming an ester that balances water and oil properties. The finished powder or liquid is filtered and purified, then added to cosmetic bases during the cool-down phase to protect its activity.

Because it blends smoothly with oils and butters, Myristyl 3-Glyceryl Ascorbate is common in moisturizers, anti-aging serums, brightening creams, sleeping masks, eye treatments and even tinted sunscreens that aim to fight dullness while keeping skin hydrated.

Myristyl 3-Glyceryl Ascorbate’s Cosmetic Benefits/Uses

This ingredient pulls double duty in skin care formulas

  • Antioxidant – Vitamin C helps neutralize free radicals created by UV light and pollution which can lead to dark spots and early wrinkles. By protecting the skin from this daily stress the ingredient supports a brighter, more even tone
  • Humectant – The glycerin part attracts water from the air and deeper skin layers then holds it at the surface. This boost of moisture can leave skin feeling softer and looking plumper helping smooth fine lines caused by dryness

Who Can Use Myristyl 3-Glyceryl Ascorbate

Because this ingredient balances oil loving and water loving traits it tends to suit most skin types including dry, normal, combination and oily. The humectant side helps thirsty or mature skin while the lightweight fatty chain prevents the tight feel that some vitamin C serums leave behind. Sensitive skin usually tolerates it better than pure ascorbic acid, though a small number of users may still notice mild tingling due to its vitamin C content.

Myristyl 3-Glyceryl Ascorbate is made from plant derived vitamin C, glycerin and myristyl alcohol so it can be sourced and processed entirely from non animal materials. Products that state their glycerin and fatty alcohol are vegetable based will therefore be suitable for vegans and vegetarians.

Topical vitamin C derivatives like this one are generally considered low risk during pregnancy and breastfeeding because the body already encounters vitamin C through food and supplements. That said this is not medical advice and anyone who is pregnant or nursing should show new skincare products to a qualified health professional before use.

The ingredient does not make skin more sensitive to the sun. In fact its antioxidant action can add a little extra daytime protection when layered under sunscreen. There are no known issues with hair care or body care formulas that contain it so long as the finished product stays within the usual pH range for skin.

Potential Side Effects/Adverse Reactions

Reactions to topical Myristyl 3-Glyceryl Ascorbate differ from person to person. The points below list potential side effects, most of which are rare when a product is well formulated and used as directed.

  • Mild stinging or warmth on application, especially on freshly exfoliated skin
  • Temporary redness or flushing in very reactive skin
  • Itchiness or hives signalling an allergic response to vitamin C or another formula component
  • Clogged pores or breakouts in individuals who are extremely acne prone and sensitive to fatty alcohols
  • Yellowing of the product over time which can transfer a faint tint to light fabrics
  • Increased sensitivity if layered with strong exfoliating acids or retinoids without adequate spacing

If any irritation, rash or other unexpected reaction develops stop using the product immediately and seek advice from a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 1 out of 5

Myristyl 3-Glyceryl Ascorbate earns a low score because it is used in small percentages and its fatty tail is balanced by the water-attracting glycerin and vitamin C portions, so it does not readily sit in pores or form heavy films. Most users, including those with oily or combination skin, find it lightweight and non-greasy. Only people who are extremely reactive to any fatty alcohol derivative might notice congestion, but this is uncommon.

In short, the ingredient is generally suitable for acne-prone or breakout-prone skin, provided the overall formula stays light and oil levels are well controlled by the manufacturer.

As with all cosmetic ingredients, the finished product’s full roster of oils, waxes and silicones will ultimately decide how pore-friendly it feels.

Summary

Myristyl 3-Glyceryl Ascorbate brings antioxidant protection and lasting hydration in one molecule. The vitamin C core scavenges free radicals to brighten skin and defend against environmental stress while the glycerin moiety pulls in moisture and the myristyl chain helps the ingredient sit comfortably in creamy bases, boosting skin softness.

It enjoys moderate popularity, showing up most often in Japanese and Korean moisturizers and brightening serums, though Western brands are beginning to pick it up as consumers look for gentler vitamin C options.

Overall safety is high, with low irritation rates and no links to serious adverse effects when used as directed. Still, every skin is unique so it is smart to do a small patch test when trying any new product that contains this multitasking derivative.

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