Myristyl Hydroxyethyl Imidazoline: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Myristyl Hydroxyethyl Imidazoline?

Myristyl Hydroxyethyl Imidazoline is a specialty ingredient made by joining a long-chain fatty acid called myristic acid with a small nitrogen-containing ring known as an imidazoline, then adding a hydroxyethyl group that improves water compatibility. Myristic acid is usually sourced from coconut or palm kernel oil so the final compound starts with a plant-based feedstock.

Chemists first explored imidazoline derivatives in the 1950s while looking for gentler alternatives to soap in textile processing. Their softening and static-reducing properties soon caught the eye of personal care formulators who adapted the molecule for hair products. Today it is produced on an industrial scale by heating myristic acid with amino alcohols under controlled conditions that promote ring formation, followed by purification to remove excess reactants and ensure cosmetic-grade purity.

You will most often spot Myristyl Hydroxyethyl Imidazoline in rinse-off and leave-in hair products such as shampoos, conditioners, masks, detangling sprays, styling creams and anti-frizz serums. Its ability to reduce flyaways while leaving hair smooth makes it a popular choice in everyday and salon formulations alike.

Myristyl Hydroxyethyl Imidazoline’s Cosmetic Benefits/Uses

This ingredient delivers two main perks when added to a hair formulation

  • Antistatic – helps neutralize electrical charges that build up on hair strands so they repel each other less which cuts down on flyaways and frizz, making hair easier to manage and style
  • Hair Conditioning – coats the cuticle with a light layer that feels silky, improves slip for easier combing and adds a soft touch without heavy buildup

Who Can Use Myristyl Hydroxyethyl Imidazoline

Because it is classed as a mild conditioning antistatic agent, Myristyl Hydroxyethyl Imidazoline can be used by most scalp and hair types including normal, dry, oily and color treated hair. People with very sensitive or allergy-prone skin should be aware that any cationic conditioning agent can on rare occasions trigger irritation so they may want to choose formulas with lower concentrations or fragrance-free bases.

The fatty acid portion is typically sourced from coconut or palm kernel oil so production does not rely on animal inputs, making the ingredient suitable for vegans and vegetarians as long as the finished product is certified cruelty-free.

No evidence links this molecule to hormonal disruption or systemic absorption, so pregnant or breastfeeding women can generally use products containing it. This is not medical advice and anyone who is expecting or nursing should clear all personal care products with their healthcare provider just to be safe.

Myristyl Hydroxyethyl Imidazoline is not known to cause photosensitivity and does not make skin or hair more prone to sun damage. It also plays well with common hair actives like proteins, silicones and plant extracts, so compatibility issues are minimal.

Potential Side Effects/Adverse Reactions

Side effects and reactions to the topical use of Myristyl Hydroxyethyl Imidazoline vary from person to person. The points below list potential effects yet most users will not experience them when the ingredient is blended correctly into a well-formulated product.

  • Mild scalp or skin irritation such as redness itching or a stinging sensation
  • Allergic contact dermatitis in individuals sensitive to imidazoline derivatives
  • Eye irritation if rinse-off lather or leave-in spray accidentally gets into the eyes
  • Product buildup leaving hair feeling weighed down if used in very high amounts or not rinsed thoroughly

If you notice any of the above reactions discontinue use and consult a medical professional if symptoms persist or worsen.

Comedogenic Rating

Rating: 1/5 – Myristyl Hydroxyethyl Imidazoline is a water compatible, cationic conditioning agent that tends to sit on the hair shaft rather than penetrating facial pores. It is normally used in rinse off or light leave in hair products where skin contact is brief or minimal. Because the molecule is larger and more polar than plain myristic acid, it is far less likely to clog pores.

Most people who are prone to acne can use products containing this ingredient without seeing an uptick in breakouts.

The only caveat is for those who apply rich styling creams directly along the hairline or use heavy multitasking balms that double as skin creams. In that case the low but non-zero risk of pore congestion may become more relevant

Summary

Myristyl Hydroxyethyl Imidazoline conditions hair and tames static by forming a light, positively charged film that smooths the cuticle and neutralizes the negative charges that cause flyaways. The result is softer, easier to detangle hair with a touch of shine.

While not as famous as silicones or quaternary ammonium compounds, this ingredient has carved out a steady niche in shampoos, conditioners, masks and detangling sprays because formulators appreciate its balance of performance and mildness.

Current safety data show a low irritation profile, no evidence of hormonal disruption and minimal comedogenicity. Still, skin and scalp sensitivities vary so it is smart to patch test any new product that features Myristyl Hydroxyethyl Imidazoline before making it part of your regular routine

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