Niacinamide Lactate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Niacinamide Lactate?

Niacinamide lactate is a compound made by pairing niacinamide, a form of vitamin B3, with lactic acid, the gentle alpha hydroxy acid found in fermented foods and some fruits. The result, known by chemists as 3-pyridinecarboxamide 2-hydroxypropanoate, delivers the skin friendly traits of both molecules in a single, stable ingredient. It first appeared in cosmetic labs as formulators searched for ways to boost the performance of standard niacinamide while keeping irritation low. By creating a salt with lactic acid, scientists found they could improve water solubility and skin feel, making it easier to slip into light lotions and serums.

Commercial production starts with pharmaceutical grade niacinamide fermented lactic acid and a neutralization step that bonds them together. The process is relatively mild, so the final ingredient retains the beneficial profiles of each component. You will commonly spot niacinamide lactate in daily moisturizers, brightening serums, anti-aging creams, sheet masks and leave-on treatments aimed at smoothing texture and strengthening the skin barrier.

Niacinamide Lactate’s Cosmetic Benefits/Uses

This ingredient is prized for its skin conditioning ability, meaning it supports a healthy, comfortable complexion. In formulas it helps reinforce the moisture barrier which can reduce water loss and dryness. Regular use may soften rough patches, even out tone and leave skin feeling supple and resilient.

Who Can Use Niacinamide Lactate

Niacinamide lactate is generally suitable for all skin types including dry, oily, combination and sensitive because it delivers hydration without heavy oils and it is formulated at a gentle pH. Those with ultra reactive skin or a known allergy to niacinamide or lactic acid should approach with caution, as even the mildest form can still trigger irritation in rare cases.

The ingredient is made through synthetic processing of vitamin B3 and fermentation derived lactic acid with no animal by-products, so it fits vegan and vegetarian lifestyles.

Current research shows no specific risks for pregnant or breastfeeding women when niacinamide lactate is used topically, yet this is not medical advice. Anyone who is expecting or nursing should confirm suitability with a healthcare professional before adding new products.

Unlike strong exfoliating acids, niacinamide lactate does not increase photosensitivity. Standard daytime SPF habits are still encouraged, but there is no unique need for extra sun precautions when using this ingredient.

Potential Side Effects/Adverse Reactions

Reactions to topical niacinamide lactate differ from person to person. The points below outline potential side effects, though most users will not encounter them when the ingredient is correctly formulated and applied.

  • Temporary redness or warmth, sometimes called a niacin flush
  • Mild stinging or tingling on sensitive or compromised skin
  • Itchiness or minor swelling indicating irritation
  • Breakouts in individuals prone to purging when introducing new actives
  • Allergic contact dermatitis marked by persistent rash or discomfort
  • Increased irritation when layered immediately with low-pH acids or strong retinoids

If any of these effects occur persistently or worsen, stop use and seek guidance from a qualified healthcare professional.

Comedogenic Rating

Comedogenic rating: 0 out of 5. Niacinamide lactate is highly water-soluble and contains no heavy oils or waxes that could block follicles. Both niacinamide and lactic acid individually score at or near zero, so their paired salt keeps the same pore-friendly profile. Light molecular weight and quick absorption mean residue is minimal, leaving little chance for buildup.

This makes the ingredient suitable for people who are prone to acne or frequent breakouts.

Because it is usually formulated at a balanced pH, the salt also avoids the rebound oiliness that some harsh actives can trigger, further lowering comedogenic risk.

Summary

Niacinamide lactate conditions skin by reinforcing the moisture barrier, smoothing texture and helping to even tone. It does this through the vitamin B3 side, which supports ceramide production and calms redness, and the lactate side, which attracts water and keeps the salt comfortably acidic for skin compatibility.

While standard niacinamide is already popular, its lactate form is just starting to appear in newer serums and light creams as brands look for upgraded versions with improved feel and solubility. Early feedback is positive, suggesting the ingredient will gain traction in the coming years.

Overall safety is high, with low irritation and a non-comedogenic profile, but every skin is unique so it is smart to patch test any new product that features niacinamide lactate before full-face use.

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