Nitroethane: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Nitroethane?

Nitroethane is an organic liquid made of two carbon atoms, five hydrogen atoms and one nitro group attached to the chain. It belongs to the family of nitro alkanes and looks like a clear colorless fluid with a mild sweet smell. First prepared in the mid-1800s, nitroethane found its way into industry as a solvent for waxes, fats and resins. Over time formulators noticed its ability to dissolve a wide range of ingredients quickly, which opened the door to cosmetic use.

Commercially nitroethane is produced by reacting propane with nitric acid under carefully controlled temperatures. The reaction mixture is then purified and distilled to isolate the nitroethane fraction. The result is a high-purity solvent that blends easily with water, alcohol and many oils.

In cosmetics you will most often see nitroethane in fast-drying products that need a reliable carrier for pigments, fragrances or film formers. Typical examples include nail polishes, nail polish removers, hair sprays, setting lotions, temporary tattoo inks and some specialty makeup products where smooth even application is key.

Nitroethane’s Cosmetic Benefits/Uses

Below is the main role nitroethane plays when added to beauty formulas.

Solvent: Its primary job is to dissolve hard-to-mix ingredients so they spread evenly through the product. By keeping pigments, resins and oils in a stable liquid state, nitroethane helps a formula apply smoothly, dry faster, feel lighter on skin or nails and resist streaking or clumping.

Who Can Use Nitroethane

Nitroethane is generally suitable for normal, combination and oily skin because it evaporates quickly and leaves little residue. People with very dry or sensitive skin might find it a bit drying as it can pull some natural oils from the surface during evaporation, which may lead to tightness or mild flaking if used often.

The ingredient is made synthetically from petroleum feedstocks and does not rely on animal products or by-products, so it is considered vegan and vegetarian friendly.

Current safety data on topical use during pregnancy and breastfeeding are limited. There is no clear evidence of harm, but out of an abundance of caution pregnant or nursing individuals should ask a qualified medical professional before using products that contain nitroethane. This is not medical advice and personal medical guidance should always come from a doctor.

Nitroethane does not make skin more sensitive to sunlight and it has no known effect on melanin production, so extra sun protection is not required beyond normal daily habits.

Potential Side Effects/Adverse Reactions

Reactions to nitroethane vary from person to person. The effects listed below are only potential outcomes and are unlikely for most users when the ingredient is included at appropriate levels in a well-formulated product.

  • Skin irritation: May present as mild redness, tingling or stinging shortly after application, especially on already irritated or broken skin
  • Dryness or cracking: Fast evaporation can strip some surface oils leading to temporary dryness on nails or skin around the application site
  • Allergic contact dermatitis: Rare cases of itching, rash or swelling in individuals who develop sensitivity to nitro compounds
  • Eye irritation: Vapors or accidental splashes can cause watering, burning or redness of the eyes
  • Headache or dizziness from fumes: Strong or prolonged inhalation in poorly ventilated spaces may trigger lightheadedness or headaches

If you experience any of these effects stop using the product immediately and seek medical advice if symptoms persist or worsen.

Comedogenic Rating

Rating: 0 (non-comedogenic)

Nitroethane is a lightweight volatile solvent that flashes off the skin or nails within seconds, so it does not sit in pores or leave a film that could trap sebum and debris. Because it lacks heavy oils or waxes its potential to block follicles is essentially nil, earning it a 0 on the comedogenic scale. This makes it generally suitable for people who are prone to acne or breakouts.

Keep in mind that a finished product’s pore-clogging potential also depends on the other ingredients in the formula. A polish or spray rich in resins or plasticizers could still contribute to bumps even though nitroethane itself does not.

Summary

Nitroethane acts mainly as a fast-evaporating solvent, dissolving pigments, resins and fragrances so they spread evenly then dry in a smooth uniform film. Its quick flash-off speeds up setting time, helps prevent streaks and keeps textures light.

The ingredient is fairly niche in cosmetics; you will see it more in nail products, some hair sprays and occasional specialty makeup rather than everyday skin care. Within those categories formulators value it for reliability and speed.

When used at the low concentrations typical of cosmetic formulas nitroethane is considered safe for healthy adults, though it can irritate very sensitive or broken skin and its vapors may bother those working in closed spaces. As with any new product it is wise to perform a small patch test first to check personal tolerance.

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