Octyldodeceth-2: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Octyldodeceth-2?

Octyldodeceth-2 is a synthetic ingredient made by reacting a fatty alcohol called octyldodecanol with a small amount of ethylene oxide. The result is a lightweight molecule that has both oil-loving and water-loving parts, which makes it useful for blending different phases in a formula. The process, known as ethoxylation, has been used in the cosmetic industry since the late twentieth century to create gentle yet effective surfactants and emulsifiers. Because the raw materials are readily available from plant-sourced fatty alcohols or petrochemical feedstocks, Octyldodeceth-2 can be produced on a large scale with consistent quality. You will most often find it in lotions, creams, hydrating serums, sunscreens, makeup removers, sheet masks and leave-on treatments where a smooth, uniform texture is essential.

Octyldodeceth-2’s Cosmetic Benefits/Uses

This ingredient is valued mainly for its emulsifying ability. By keeping oil and water evenly mixed, it stops products from separating, improves their shelf life and creates a silky feel when applied to the skin. Stable emulsions spread more easily, deliver active ingredients more evenly and help the finished product look and feel elegant.

Who Can Use Octyldodeceth-2

Because Octyldodeceth-2 is primarily an emulsifier and is used at low concentrations, it is generally well tolerated by most skin types including oily, dry, combination and normal skin. Sensitive or compromised skin may want to proceed carefully since any surfactant-like substance can occasionally disturb an already weakened barrier, but reports of irritation are rare.

The ingredient is made synthetically from fatty alcohols that can be sourced from plants or petroleum and involves no animal-derived inputs, so it is considered suitable for vegans and vegetarians.

Current safety data indicate no specific risks for women who are pregnant or breastfeeding when Octyldodeceth-2 is used topically in cosmetics. This is not medical advice and anyone who is pregnant or nursing should check with a healthcare professional before adding new products to their routine.

Octyldodeceth-2 does not cause photosensitivity and can be used in both day and night products without increasing the skin’s vulnerability to the sun.

Potential Side Effects/Adverse Reactions

Reactions to topical Octyldodeceth-2 differ from person to person. The points below outline potential side effects that could occur, but most users should not expect to encounter them when the ingredient is formulated and used correctly.

  • Mild skin irritation
  • Redness or warmth at the application site
  • Stinging when applied to broken or highly sensitive skin
  • Eye irritation if the product accidentally enters the eyes
  • Enhanced penetration of other actives that might themselves be irritating

If any of these effects occur stop using the product and consult a qualified healthcare professional.

Comedogenic Rating

Rating: 1 out of 5. Octyldodeceth-2 is derived from a fatty alcohol yet its ethoxylated structure keeps it light and water compatible, which limits the chance of forming a heavy film on the skin. It is used at low levels and is rinsed or absorbed quickly, so it rarely blocks pores. As a result, most people prone to acne or breakouts can use products containing this ingredient without added concern. While individual responses vary, there is no strong evidence linking Octyldodeceth-2 to increased comedone formation.

Summary

Octyldodeceth-2 acts primarily as an emulsifier, keeping oil and water blended so lotions, creams and serums stay smooth, stable and pleasant to apply. Its dual affinity for both phases allows actives to spread evenly and improves the overall feel of a formula. Although it is not a headline ingredient, chemists value it for quietly doing its job in a wide range of products you see on shelves every day.

Current data show it has a low irritation profile, a very low comedogenic rating and no known long-term safety issues when used in cosmetics. As with any new skincare product it is wise to perform a small patch test first to be sure your skin agrees with the full formula.

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