Octyldodeceth-5: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Octyldodeceth-5?

Octyldodeceth-5 is a synthetic liquid ingredient made by attaching about five units of ethylene oxide to a branched fatty alcohol called octyldodecanol. The result is a clear to pale yellow substance that mixes well with both oil and water. Chemists first explored this class of ingredients in the late twentieth century while searching for gentle helpers that could keep creams from separating. Over time Octyldodeceth-5 proved reliable, easy to work with and mild on skin so it found a permanent place in modern cosmetic labs.

The manufacturing process starts with plant-derived or petroleum-derived octyldodecanol. This fatty alcohol is reacted with controlled amounts of ethylene oxide in the presence of heat and a catalyst. The reaction adds short chains of polyethylene glycol to the alcohol head, giving the molecule its balancing act between oil friendly and water friendly parts. After purification the ingredient is blended into cosmetic bases.

Because it can quietly hold oily and watery parts together, Octyldodeceth-5 shows up in many leave-on and rinse-off products. You will find it in moisturizers, sunscreens, lightweight serums, facial masks, makeup removers, hair conditioners and color cosmetics where it stabilizes the mix and improves feel.

Octyldodeceth-5’s Cosmetic Benefits/Uses

In formulas this ingredient serves one main purpose that delivers several user-friendly benefits.

As an emulsifying agent Octyldodeceth-5 helps oil and water stay blended which keeps creams smooth and consistent from the first pump to the last. A stable emulsion spreads evenly on skin so actives are delivered where they are needed and textures feel light not greasy. By preventing phase separation it also extends shelf life and reduces the need for heavy waxes leaving the final product more elegant and comfortable to wear.

Who Can Use Octyldodeceth-5

Because it is lightweight and non occlusive, Octyldodeceth-5 is generally suitable for all skin types including dry, normal, combination, oily and sensitive. It does not add significant oil or wax so it rarely feels heavy on oily complexions and its gentle nature means sensitive or reactive skin usually tolerates it well. Those with known polyethylene glycol sensitivities should be cautious since the molecule contains short PEG chains.

Source materials can be plant derived or petroleum derived, neither of which involve animal by products, so the ingredient itself is considered suitable for vegans and vegetarians when the finished formula is certified cruelty free.

Current safety data show no specific concerns for women who are pregnant or breastfeeding when Octyldodeceth-5 is used at the low percentages common in cosmetics. This is not medical advice and anyone who is pregnant or nursing should review all personal care products with a healthcare professional to be safe.

The ingredient does not make skin more sensitive to sunlight and has no known interactions with UV exposure. It is also fragrance free and colorless which further reduces the likelihood of irritation for fragrance sensitive users.

Potential Side Effects/Adverse Reactions

Reactions to topical Octyldodeceth-5 can vary from person to person. The following points list potential side effects though most users will not experience them when the ingredient is used correctly in a well formulated product.

  • Mild skin irritation such as redness or stinging in very sensitive individuals
  • Allergic contact dermatitis in people allergic to polyethylene glycols or similar surfactants
  • Transient eye irritation if the product accidentally gets into the eyes
  • Enhanced penetration of other actives which could amplify their effects in rare cases

If you notice any persistent discomfort or unexpected reaction discontinue use and consult a qualified healthcare professional.

Comedogenic Rating

Rating: 1/5

Octyldodeceth-5 is structurally light and contains short polyethylene glycol chains that rinse cleanly, so it does not linger on pores or form heavy films. Published data and formulator experience show it rarely contributes to clogged pores, which is why it earns a low score of 1. Its main job is to keep oil and water mixed rather than to sit on the skin as an occlusive layer, further reducing the chance of congestion. Those prone to acne or breakouts usually tolerate it well, though individual responses can differ.

The rating can climb if the ingredient is paired with richer oils or waxes in a formula, since the overall product texture then becomes heavier, but Octyldodeceth-5 on its own remains low risk.

Summary

Octyldodeceth-5 is a reliable emulsifier that keeps creams, lotions and serums smooth by bridging the gap between oil and water. Its balanced structure lets it disperse evenly so products feel lighter and more elegant while still staying stable on the shelf. You will see it in a variety of skincare and haircare items, though it is more of a supporting actor than a headline ingredient which is why it is not a household name.

Current safety assessments rate it as low irritation at the small percentages used in cosmetics, and it carries minimal comedogenic risk for most skin types. As with any new product a quick patch test is wise to make sure your skin agrees before full application.

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