Octyldodecyl Myristate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Octyldodecyl Myristate?

Octyldodecyl Myristate is an oily liquid made by joining myristic acid, a fatty acid found in coconut and palm kernel oil, with a long chain alcohol called octyldodecanol. The result is a lightweight ester that feels silky on skin.

Cosmetic chemists began working with this ester in the late 1970s while looking for plant-derived alternatives to heavier mineral oils. Its smooth texture and stability quickly earned it a spot in modern formulations.

The ingredient is produced through a process called esterification, where myristic acid reacts with octyldodecanol under heat and a catalyst. The finished material is then purified and tested for quality before it reaches manufacturers.

You will most often see Octyldodecyl Myristate in facial and body moisturizers, makeup primers, cream foundations, sunscreens, hair conditioners, anti-aging lotions and wash-off masks. Brands like it because it spreads easily, boosts softness and does not leave a greasy afterfeel.

Octyldodecyl Myristate’s Cosmetic Benefits/Uses

Formulators turn to this ingredient for one key job that makes products feel better and perform smoothly on skin.

As an emollient, Octyldodecyl Myristate fills in tiny gaps between skin cells to create a soft even surface. This helps reduce roughness, improves spreadability of creams and foundations, enhances a silky finish and can give dry skin an instant sense of comfort without heaviness.

Who Can Use Octyldodecyl Myristate

This silky ester works well for most skin types, especially dry, normal and mature skin that crave extra softness. Its slip and cushioning feel can also benefit combination skin in drier areas. Those with very oily or acne-prone complexions may want to tread carefully because the ingredient has a higher tendency to clog pores, which can trigger or worsen breakouts in that group.

Octyldodecyl Myristate is considered suitable for both vegans and vegetarians because the fatty acid and alcohol used to create it are typically sourced from coconut, palm or other plant oils, not animal by-products.

No data suggest the ester poses specific risks for pregnant or breastfeeding women when used topically in cosmetic amounts. Still, this is not medical advice and anyone who is pregnant or nursing should show their health-care provider any product they plan to use, just to be on the safe side.

The ingredient is non-photosensitizing, so it will not increase sensitivity to sunlight. Beyond that, it has no known interactions with common actives such as retinoids, alpha hydroxy acids or vitamin C, making it easy to slot into most routines.

Potential Side Effects/Adverse Reactions

Reactions to topical Octyldodecyl Myristate differ from person to person. The following outlines potential side effects users could experience, though these outcomes are uncommon when the ingredient is formulated and used correctly.

Pore clogging and breakouts

Worsening of existing acne, particularly on oily skin

Mild skin irritation such as redness or itching

Rare cases of contact allergy marked by swelling or rash

Eye irritation if the product accidentally gets into the eyes

If any adverse reaction occurs, stop using the product and consult a dermatologist or qualified medical professional for guidance.

Comedogenic Rating

Octyldodecyl Myristate scores a 4 out of 5 on the comedogenic scale. Its long fatty acid chain can sit on the skin and mix with sebum, which makes it easier to block pores. Formulas that use it at high levels or in rich textures are more likely to trigger congestion in people already prone to blackheads or pimples. Those who break out easily may prefer to avoid it or use it only in rinse-off products. Concentration, overall formula balance and how thoroughly the skin is cleansed afterward can all influence whether clogging actually occurs.

Summary

Octyldodecyl Myristate is mainly an emollient that smooths rough patches, improves spreadability and leaves a silky afterfeel. It does this by filling tiny spaces between skin cells and creating a thin cushioning layer that locks in moisture without a heavy greasy film. Its pleasant slip, stability and plant-derived origin have kept it popular in moisturizers, foundations, primers and sunscreens since the late 1970s, although it is not as buzzworthy as newer exotic oils or lab-engineered silicones.

Overall it is considered safe for topical use with low risk of irritation or sensitization, but its higher comedogenic rating means acne-prone users should be cautious. As with any new cosmetic ingredient, patch test first to see how your own skin responds.

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