Oleamine Oxide: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Oleamine Oxide?

Oleamine Oxide, scientifically named N,N-Dimethyl-9-(Z)-octadecenamine-N-oxide, is a mild surfactant derived from oleic acid, a fatty acid commonly obtained from vegetable oils such as olive, soybean and sunflower. Chemically, it belongs to the family of amine oxides, molecules valued for their gentle cleansing action and ability to enhance foam.

The ingredient was first explored in the mid-20th century when formulators searched for alternatives to harsher sulfated surfactants. As consumer demand grew for products that clean effectively without stripping skin or hair, Oleamine Oxide gained popularity thanks to its balanced mix of cleansing power and softness. Today it is manufactured through a two-step process: oleic acid is converted to an amine, then that amine undergoes controlled oxidation to create the final amine oxide form. The result is a biodegradable, water-soluble ingredient with a neutral scent and a clear to pale-yellow appearance.

Because of its versatility, Oleamine Oxide shows up in many rinse-off and leave-on formulas. It is commonly found in facial cleansers, micellar waters, body washes, bubble baths, shampoos, co-wash creams, conditioning masks, scalp scrubs, hand soaps and even some makeup brush cleansers. Its ability to boost foam while remaining gentle makes it especially attractive in products marketed for sensitive skin or color-treated hair.

Oleamine Oxide’s Cosmetic Benefits/Uses

In formulations Oleamine Oxide offers several performance benefits:

  • Cleansing: Acts as a primary or supporting surfactant, lifting away dirt, oil and product buildup without leaving skin or hair feeling tight
  • Foam Boosting: Enhances the volume and stability of foam, giving shampoos and body washes a rich, cushiony lather that users associate with effective cleaning
  • Hair Conditioning: Deposits a light, positively charged layer that smooths the cuticle, reduces static flyaways and improves combability
  • Antistatic: Neutralizes static charge on hair and certain skin care formulas, helping strands lie flat and fabrics glide smoothly over skin
  • Hydrotrope: Increases the solubility of fragrance oils, essential oils and other low-water-soluble ingredients, allowing formulators to create clear stable products without extra solvents

Who Can Use Oleamine Oxide

Oleamine Oxide is regarded as gentle enough for most skin types including dry, normal, combination and oily skin. Its mild cleansing action and low irritation profile make it especially appealing for sensitive or easily reddened skin. There are no specific skin types for which it is considered unsuitable, although people with a known allergy to amine oxides should avoid it.

The ingredient is typically sourced from vegetable oils so it is usually suitable for vegans and vegetarians. Anyone following a strict plant-based lifestyle should still verify the raw material origin with the brand since in rare cases fatty acids can come from animal tallow.

Current safety data suggest Oleamine Oxide poses minimal risk for women who are pregnant or breastfeeding because systemic absorption from topical use is expected to be very low. This is not medical advice and anyone who is pregnant or nursing should discuss any skincare product with a healthcare professional before use to be safe.

Oleamine Oxide does not make skin more sensitive to the sun and there are no known interactions with UV exposure. Because it is biodegradable and free of strong fragrance, it is also a good option for people trying to reduce environmental impact or avoid added scent.

Potential Side Effects/Adverse Reactions

Side effects and reactions to topically applied Oleamine Oxide can vary from person to person. The following is a list of potential side effects that are possible yet uncommon when the ingredient is used at typical cosmetic levels in well-formulated products. Most users will not experience these issues.

  • Mild skin irritation such as redness stinging or itching, especially if the product is left on the skin for an extended time
  • Eye irritation if the raw ingredient or a high-foaming product accidentally gets into the eyes
  • Dryness or a squeaky feel on very dehydrated skin or hair when used in high concentrations or without adequate conditioning agents
  • Allergic contact dermatitis in people who are hypersensitive to amine oxide structures
  • Scalp or hair buildup giving a slightly coated feeling if the product is not rinsed thoroughly

If any persistent burning itching swelling or rash occurs stop using the product and consult a healthcare professional.

Comedogenic Rating

Rating: 1/5

Oleamine Oxide is water soluble and functions mainly on the skin’s surface as a mild cleanser and foam booster. Because it is quickly rinsed away and does not leave an oily film it has a very low tendency to block pores. For that reason it earns a rating of 1 out of 5, meaning it is considered practically non-comedogenic.

People who are prone to acne or breakouts can generally use products containing Oleamine Oxide without worrying about clogged pores.

One extra point to note is that the ingredient is often paired with heavier emollients in creamy cleansers or masks. If breakouts occur the other ingredients are more likely to be the culprits rather than Oleamine Oxide itself.

Summary

Oleamine Oxide acts as a gentle cleanser, foam booster, hair conditioner, antistatic agent and hydrotrope. It lifts away dirt and oil while adding a cushiony lather, smooths hair cuticles to reduce flyaways and helps dissolve fragrance oils so formulas stay clear and stable. All of this is accomplished through its amine oxide head that attracts water and its fatty tail that grabs onto oils, letting grime rinse off easily.

The ingredient shows up in a fair number of shampoos, body washes and micellar waters but it is not as famous as sulfates or coco-betaines. Its mild nature has earned it a steady following among brands that cater to sensitive skin and eco-conscious shoppers.

Current data rates Oleamine Oxide as low risk for irritation or systemic issues. Most people can use it safely though, as with any new product, doing a quick patch test is a smart step before full use.

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