Oligopeptide-180 Porphyra 334: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: June 30, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Oligopeptide-180 Porphyra 334?

Oligopeptide-180 Porphyra 334 is a lab-made complex that joins a short chain of amino acids (Oligopeptide-180) with Porphyra 334, a UV-absorbing molecule originally found in red algae commonly known as nori. By combining the peptide’s skin-renewing properties with Porphyra 334’s natural photo-protection, chemists created a versatile ingredient that supports both skin care and hair care goals.

The ingredient is produced through controlled peptide synthesis. First, Oligopeptide-180 is built step by step from individual amino acids. Porphyra 334 is then attached using peptide-bond technology, followed by purification and drying into a stable powder that can be blended into cosmetic formulas.

Since its debut in advanced Korean skin care a little over a decade ago, Oligopeptide-180 Porphyra 334 has gained attention for boosting sunscreen performance while offering antioxidant and conditioning benefits. Today you will find it in daily sunscreens, anti-aging serums, brightening essences, after-sun gels, hydrating sheet masks, leave-in hair treatments, color-protect shampoos and high-end moisturizers.

Oligopeptide-180 Porphyra 334’s Cosmetic Benefits/Uses

This multi-talented ingredient can play several roles in a formula

  • Antioxidant: Helps neutralize free radicals created by UV light and pollution which can lead to dullness and premature wrinkles
  • Hair conditioning: Forms a light film on strands to smooth cuticles, improve softness and support color retention
  • Skin conditioning: Supports a smoother feel and plumper look by attracting moisture and encouraging healthy protein production
  • Skin protecting: Reinforces the skin’s surface barrier so it can better defend itself against external stressors such as wind or urban dust
  • UV filter: Absorbs part of the sun’s UVA and UVB rays to lower the risk of photo-damage and enhance overall SPF performance

Who Can Use Oligopeptide-180 Porphyra 334

Because it is non greasy and lightweight, Oligopeptide-180 Porphyra 334 suits dry, normal, combination and oily skin alike. Its mild nature also makes it friendly for sensitive skin, though anyone with a known algae or peptide allergy should be cautious.

The peptide complex is produced entirely in the lab with no animal-derived materials, making it acceptable for both vegans and vegetarians.

No data suggest any specific risk for pregnant or breastfeeding women. Still this is not medical advice and anyone expecting or nursing should show the ingredient list to a qualified doctor before adding new products.

Unlike some acids or essential oils, Oligopeptide-180 Porphyra 334 does not trigger photosensitivity. In fact it does the opposite by absorbing part of the sun’s rays and supporting sunscreen filters. That said daily broad-spectrum SPF is always recommended.

Potential Side Effects/Adverse Reactions

Side effects and reactions to the topical use of Oligopeptide-180 Porphyra 334 can vary from person to person. The points below list potential issues only; most people will not notice any problems when the ingredient is used at the approved levels in a well-formulated product.

  • Mild redness or stinging on very sensitive skin
  • Itchiness or small rash in individuals allergic to algae or specific peptides
  • Eye irritation if the formula is accidentally rubbed into the eyes
  • In rare cases contact dermatitis when combined with other strong actives such as high-level exfoliating acids

If any irritation or other unwanted reaction appears stop using the product and consult a healthcare professional if symptoms persist or worsen.

Comedogenic Rating

Rating: 0 / 5

Oligopeptide-180 Porphyra 334 is water soluble with no oily or waxy residues, so it does not block pores or leave a film that traps sebum. Peptides and algae-derived filters are generally considered non-comedogenic by industry standards, which is why the rating sits at the lowest possible level.

This makes the ingredient a comfortable option for acne-prone or breakout-prone skin.

Because the peptide complex is usually included at low percentages and is often paired with lightweight gel or serum textures, its non-pore-clogging profile holds true across most finished products.

Summary

Oligopeptide-180 Porphyra 334 works as an antioxidant, mild UV filter, skin and hair conditioner and overall surface protector. The peptide portion encourages healthy protein production while Porphyra 334 absorbs part of UVA and UVB light, together helping fend off free radicals and environmental stress. At the same time it forms a light moisture-binding layer that smooths skin and softens hair strands.

Although not as famous as big-name actives like niacinamide or retinol, this hybrid molecule enjoys a steady presence in premium sunscreens, after-sun gels and color-care shampoos where formulators look for multitasking boosters that do not add heaviness.

Current data show a very low risk profile with only rare reports of irritation linked to algae or peptide allergies. Still it is wise to patch test any new product to ensure personal compatibility.

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