Peg-12 Glyceryl Dimyristate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Peg-12 Glyceryl Dimyristate?

Peg-12 Glyceryl Dimyristate is a synthetic ingredient created by attaching roughly 12 units of polyethylene glycol to glyceryl dimyristate, an ester that itself comes from glycerin and myristic acid, a fatty acid usually sourced from coconut or palm kernel oil. This combination produces a waxy, water dispersible compound that behaves like a lightweight emollient.

The cosmetic industry started exploring polyethylene glycol esters in the 1970s as formulators looked for agents that could soften skin while also helping oil and water blend smoothly. Peg-12 Glyceryl Dimyristate emerged from that research phase and has since become a staple whenever a touch of conditioning feel is needed without greasiness.

Manufacturing involves first producing glyceryl dimyristate through esterification of glycerin with myristic acid. The resulting molecule is then reacted with ethylene oxide in a controlled setting until an average of 12 ethylene oxide units are attached, giving the finished Peg-12 variant. Each batch is purified and tested for residue levels before it is cleared for use in personal care formulas.

You will most often find Peg-12 Glyceryl Dimyristate in moisturizers, face masks, anti aging serums, sunscreens, lotions, light creams, makeup primers and leave-on hair treatments where it provides a velvety finish and supports stable, even textures.

Peg-12 Glyceryl Dimyristate’s Cosmetic Benefits/Uses

Formulators reach for this ingredient mainly because of its skin feel and texture enhancing qualities.

Skin conditioning: Peg-12 Glyceryl Dimyristate forms a thin, breathable film on the surface that leaves skin feeling silky and hydrated. It smooths rough patches, helps other actives spread more evenly and reduces the chalky touch that can occur in high mineral or high water systems, resulting in a softer, more comfortable finish.

Who Can Use Peg-12 Glyceryl Dimyristate

Its light, non greasy texture makes Peg-12 Glyceryl Dimyristate a match for almost every skin type, from dry and mature to normal and combination. Oily or blemish-prone skin can usually handle it since the molecule is water dispersible and not heavy, though extremely acne-sensitive users may prefer to monitor how their skin responds.

The ingredient is synthetically produced; when manufacturers choose vegetable glycerin and plant-sourced myristic acid it is suitable for vegans and vegetarians. Because supply chains vary, strict vegan users may want to confirm the origin of the glycerin with the brand.

No data indicate that Peg-12 Glyceryl Dimyristate poses a risk during pregnancy or while breastfeeding when used topically at cosmetic levels. This is not medical advice and anyone who is pregnant or nursing should show the full ingredient list of any product to their physician for personalized guidance.

The molecule does not make skin more sensitive to sunlight so it is not considered photosensitizing. It also plays well with most other cosmetic ingredients, including acids, retinoids and sunscreens, and does not interfere with common actives.

Potential Side Effects/Adverse Reactions

Responses to any cosmetic ingredient vary from person to person. The effects listed below are potential outcomes and are unlikely for most users when the product is formulated and used as intended.

  • Mild skin irritation – rare, more likely if skin is already compromised or reactive
  • Allergic contact dermatitis – uncommon but possible in individuals with a polyethylene glycol sensitivity
  • Temporary stinging on very dry or cracked skin – usually subsides quickly once the barrier is restored
  • Eye irritation if product migrates into the eyes – rinse thoroughly with water if this occurs
  • Clogged pores in highly acne-prone users – infrequent given its low comedogenic rating but can happen in some cases

If you notice any negative reaction stop using the product and consult a healthcare professional.

Comedogenic Rating

Rating: 1/5

Peg-12 Glyceryl Dimyristate disperses in water and has a relatively small molecular size compared with heavier oils so it rinses away more easily and is less likely to settle in pores. Studies and anecdotal feedback rarely link it to persistent clogging which is why it sits close to the non-comedogenic end of the scale. Most people prone to acne or breakouts can use it without issue, though exceptionally sensitive or heavily congested skin should still keep an eye on any changes.

Because it often appears at low concentrations, the overall break-out risk is further reduced when it is blended with other lightweight emulsifiers or humectants.

Summary

Peg-12 Glyceryl Dimyristate acts mainly as a skin-conditioning agent that softens rough spots, boosts spreadability and leaves a silky after-feel without greasy residue. It achieves this by forming a thin, breathable film that locks in surface moisture while its PEG side promotes easy mixing of water and oil phases, stabilising formulas and improving texture.

It is not the most talked-about ingredient in beauty circles yet formulators value its dependable performance which is why you will quietly find it in many moisturisers, primers and lightweight creams.

Current safety assessments show a low risk of irritation or sensitisation when used at cosmetic levels making it suitable for a wide range of skin types including sensitive and acne-prone. As with any new product, patch test first to make sure your individual skin responds well.

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