Peg-20 Glyceryl Diisostearate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Peg-20 Glyceryl Diisostearate?

Peg-20 Glyceryl Diisostearate is a plant-derived ingredient made by combining glycerin with isostearic acid, then attaching about twenty units of ethylene oxide. The result is a soft, wax-like material that dissolves easily in both oil and water. Nonionic emulsifiers like this one gained popularity in the 1960s when formulators looked for gentler alternatives to soap-based surfactants. Today its consistent performance and mildness keep it in steady demand.

Production starts with vegetable oils such as coconut or soybean that are split into glycerin and fatty acids. The isostearic acid portion is reacted with glycerin to form glyceryl diisostearate. That ester is then treated with ethylene oxide until the desired “20” repeat units are reached, giving it the balance it needs to work in water-rich and oil-rich phases.

You will spot Peg-20 Glyceryl Diisostearate in facial cleansers, micellar waters, makeup removers, hydrating masks, lightweight lotions, sunscreens, baby washes and even some hair conditioners where a silky feel is needed.

Peg-20 Glyceryl Diisostearate’s Cosmetic Benefits/Uses

This multitasker improves both the feel and performance of everyday beauty products.

  • Cleansing – Acts as a gentle surfactant that loosens dirt, excess oil and makeup so they can be rinsed away without stripping skin
  • Emulsifying – Binds water and oil into a stable mixture which prevents separation, enhances texture and helps active ingredients spread evenly

Who Can Use Peg-20 Glyceryl Diisostearate

This ingredient is considered low risk for most skin types. Its mild, nonionic nature means it cleanses without stripping so it suits normal, dry, oily and combination skin. Even sensitive skin usually tolerates it well because it has a low irritation profile, though anyone with a history of allergies to polyethylene glycols should proceed with caution.

Peg-20 Glyceryl Diisostearate is synthesized from vegetable oils and contains no animal by-products, making it acceptable for vegans and vegetarians. Manufacturers sometimes use animal derived fatty acids for similar ingredients, so checking a brand’s sourcing policy is wise if strict vegan status is important.

The ingredient is not known to interfere with pregnancy or breastfeeding and it is not absorbed in meaningful amounts through intact skin. Nevertheless this is not medical advice; pregnant or nursing individuals should show the full ingredient list of any product they plan to use to their healthcare provider.

It does not increase photosensitivity and can be used in daytime formulas without raising sunburn risk. It is also compatible with leave-on and rinse-off products for both skin and hair.

Potential Side Effects/Adverse Reactions

Responses to topical Peg-20 Glyceryl Diisostearate vary from person to person. The points below describe potential side effects that are possible yet unlikely for the average user when the ingredient is properly formulated.

  • Mild redness or stinging in very sensitive skin, generally short-lived after rinsing
  • Allergic contact dermatitis in individuals already sensitized to polyethylene glycols or isostearic acid derivatives
  • Eye irritation if a cleansing product with a high concentration gets into the eyes
  • Enhanced penetration of other actives which could amplify irritation caused by stronger ingredients in the same formula
  • Trace 1,4-dioxane contamination if the manufacturer does not properly purify the ethoxylated raw material, though reputable brands test for this impurity

If you experience any of the above reactions stop using the product and seek medical guidance if symptoms persist or worsen.

Comedogenic Rating

Rating: 1 / 5

Peg-20 Glyceryl Diisostearate is derived from lightweight, highly processed fatty acids that do not solidify inside pores the way heavier, untreated oils can. Its ethoxylated structure keeps it water dispersible so it rinses away cleanly instead of lingering on the skin’s surface. For these reasons the likelihood of it clogging pores is very low, earning it a rating of 1.

Suitable for acne-prone or breakout-prone skin, especially in rinse-off formats like cleansers and micellar waters.

Keep in mind that overall formula composition matters; pairing this ingredient with heavy occlusives could still feel greasy to very oily skin.

Summary

Peg-20 Glyceryl Diisostearate serves mainly as a gentle cleanser and a reliable emulsifier. Its nonionic surfactant head loosens dirt and makeup without stripping while its dual oil-friendly and water-friendly tails hold oil and water together so lotions stay smooth and stable. This balance also helps actives spread evenly across skin.

The ingredient is a quiet workhorse rather than a buzzword, yet it appears in a steady stream of face washes, makeup removers, sunscreens and light lotions because formulators trust its mildness and consistency.

Safety data show a very low irritation profile and minimal absorption through intact skin. Formulas from reputable brands are also screened for trace 1,4-dioxane. Still, everyone’s skin is unique so patch testing a new product is the smartest way to rule out personal sensitivities.

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