Peg-220: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Peg-220?

Peg-220 is a synthetic ingredient made by linking about 220 units of ethylene oxide to create a long, water-friendly chain. This chain ends with two hydroxyl groups that help it mix well with water and oily substances. The base material, ethylene oxide, comes from petroleum or natural gas, and chemists control the number of linked units to reach the desired average of 220.

The wider family of polyethylene glycols (PEGs) has been used in cosmetics since the mid-20th century because they are versatile, stable and gentle on skin. Peg-220 entered formulas as brands searched for high-molecular-weight PEGs that deliver moisture without feeling greasy.

Production starts with purified ethylene oxide that is reacted with a starter molecule, usually water, under heat and pressure. Each reaction step adds another ethylene oxide unit until the chain hits the target length. The resulting liquid or soft solid is then filtered, tested for purity and blended into cosmetic bases.

You will most often see Peg-220 in moisturizers, hydrating masks, anti-aging serums, cleansing balms, makeup removers and leave-on treatments that aim to lock in water while keeping a smooth texture.

Peg-220’s Cosmetic Benefits/Uses

Formulators choose Peg-220 for several helpful roles that improve both product performance and skin feel.

  • Binding: Peg-220 holds together ingredients that might otherwise separate which keeps creams, gels and lotions uniform from the first use to the last.
  • Humectant: It attracts water from the environment and draws it toward the skin surface helping skin stay hydrated soft and plump.
  • Solvent: Peg-220 dissolves certain active ingredients, fragrances and colorants so they spread evenly and stay stable within the formula.

Who Can Use Peg-220

Peg-220 works for most skin types including dry, normal, combination and oily skin because its large molecular size sits on the surface and draws in water without clogging pores or leaving a heavy film. Sensitive skin usually tolerates it well since it is non-ionic and has a low irritation profile, though anyone with a history of PEG allergies should proceed carefully.

The ingredient is produced from petroleum or natural gas sources, not animals, so it is suitable for vegans and vegetarians. Reputable suppliers also avoid animal testing to meet cruelty-free standards.

Current safety data indicate no specific risks for pregnant or breastfeeding women when Peg-220 is used topically at cosmetic concentrations. This is not medical advice and anyone who is pregnant or nursing should run their skincare routine past a qualified healthcare provider to be on the safe side.

Peg-220 does not make skin more sensitive to sunlight and it has no known interactions with UV exposure, so there is no extra need for sun avoidance beyond normal daily SPF use.

Potential Side Effects/Adverse Reactions

Reactions to topical Peg-220 vary from person to person. The effects listed below are possible yet uncommon when the ingredient is used at the levels allowed in finished cosmetic products.

  • Mild redness or stinging on very sensitive or compromised skin
  • Rare allergic contact dermatitis in individuals already sensitized to PEGs
  • Over-hydration of the stratum corneum leading to temporary skin softness or maceration if applied under occlusion for prolonged periods
  • Potential impurities such as trace 1,4-dioxane if the raw material is not properly purified, though reputable brands test to keep levels far below safety limits
  • Enhanced penetration of strong active ingredients in the same formula which could intensify their effects on reactive skin

If any irritation, rash or other unexpected reaction occurs stop using the product and consult a dermatologist or healthcare professional.

Comedogenic Rating

Rating: 0 (non-comedogenic)

Peg-220 is a large water-soluble molecule that stays on the skin surface, attracts moisture and rinses away easily. It contains no fatty acids or waxy residues that could block pores, so it earns a zero rating for comedogenicity. This makes it generally suitable for people prone to acne or breakouts.

No reports link Peg-220 itself to blackheads or whiteheads. Any risk would come from other pore-clogging ingredients in the same formula, not from Peg-220.

Summary

Peg-220 acts as a binding agent, humectant and solvent. Its long hydrophilic chain locks unstable ingredients together, pulls water toward the skin and dissolves actives so they spread evenly. Because it does all three jobs without feeling greasy formulators reach for it in moisturizers, masks and cleansers, although it is less talked about than buzzier plant extracts.

Current data show Peg-220 is low risk when used at cosmetic levels with only rare irritation or allergy reports. As with any new skincare product it is smart to patch test first to confirm your skin agrees with it.

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