Peg-25 Glyceryl Isostearate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Peg-25 Glyceryl Isostearate?

Peg-25 Glyceryl Isostearate is a man-made ingredient created by reacting isostearic acid, a fatty acid normally derived from vegetable oils like coconut or soy, with glycerin and about 25 units of ethylene oxide. The result is a waxy, water-soluble compound that bridges the gap between oily and watery ingredients. It first appeared in personal care labs in the late 20th century when formulators were looking for gentler, plant-based alternatives to older synthetic surfactants. Production involves esterifying glycerin with isostearic acid, then adding controlled amounts of ethylene oxide until the desired “25 EO” average is reached, giving the molecule both oil-loving and water-loving sections. Thanks to this dual nature it shows up in a wide range of products: facial cleansers, lotions, creams, masks, makeup removers, sunscreens, light serums and even some hair conditioners where a smooth, creamy texture is needed.

Peg-25 Glyceryl Isostearate’s Cosmetic Benefits/Uses

This ingredient’s main role in skincare and haircare is as an emulsifier. By helping oil and water mix evenly it keeps a formula stable so the texture stays smooth and the active ingredients are delivered uniformly to the skin or hair. A reliable emulsifier also improves the sensory feel of a product, letting it spread easily without leaving a greasy film and supporting lightweight, fast-absorbing textures that many consumers prefer.

Who Can Use Peg-25 Glyceryl Isostearate

Because it is a mild emulsifier with a lightweight finish, Peg-25 Glyceryl Isostearate generally suits all major skin types: oily, combination, normal and dry. Sensitive skin usually tolerates it as well thanks to its nonionic nature, though anyone with a known polyethylene glycol allergy should avoid it. The ingredient is synthesized from plant-derived fatty acids and glycerin, so products formulated with it are usually appropriate for vegans and vegetarians as long as no other animal-based additives are present. Current safety data indicate no specific risks for women who are pregnant or breastfeeding, yet this is not medical advice and those individuals should confirm product choices with a physician. Peg-25 Glyceryl Isostearate does not make skin more prone to sunburn and it has no known photoreactive properties. It is odorless, colorless and free of common fragrance allergens, which helps minimize the chance of fragrance-related irritation.

Potential Side Effects/Adverse Reactions

Responses to topical Peg-25 Glyceryl Isostearate differ from person to person. The following list outlines possible but uncommon side effects when the ingredient is used at normal cosmetic levels and properly formulated.

  • Mild redness or stinging on very sensitive or damaged skin
  • Transient eye irritation if the product accidentally gets into the eyes
  • Allergic contact dermatitis in individuals allergic to polyethylene glycol compounds
  • Worsening of breakouts in extremely acne-prone users if combined with highly comedogenic oils

If any of these reactions occur stop using the product and seek medical advice if symptoms persist or worsen.

Comedogenic Rating

Rating: 1/5. Peg-25 Glyceryl Isostearate contains a fatty acid tail, yet the 25 units of ethylene oxide make it highly water compatible so it rinses away easily instead of lingering in pores. Most clinical and anecdotal data show a very low tendency to clog follicles, far lower than untreated oils or waxes. For acne-prone or breakout-prone users this ingredient is generally considered acceptable, provided the overall formula is not loaded with heavy occlusives. One extra point to note is that comedogenicity depends on the complete product, not a single component, so the presence of Peg-25 Glyceryl Isostearate alongside decidedly pore-clogging oils could still pose an issue.

Summary

Peg-25 Glyceryl Isostearate is mainly an emulsifier that holds oil and water together, stabilises textures and improves spreadability. Its split personality—fatty acid for lipophilic attraction and long PEG chain for water affinity—lets it create silky creams, fluid lotions and clear cleansing oils without greasy drag.

It is moderately popular in modern skincare because it offers plant-based origins, reliable performance and a pleasant skin feel, though it competes with many newer green emulsifiers so it is not as ubiquitous as classic PEG-derived surfactants.

Current research shows it is safe for most skin types, vegan friendly and generally non-irritating. Still, individual sensitivities vary and it is wise to patch test any new product that contains it before full-face use.

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