Peg-4/Ppg-1 Pentaerythrityl Tetraacrylate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Peg-4/Ppg-1 Pentaerythrityl Tetraacrylate?

Peg-4/Ppg-1 Pentaerythrityl Tetraacrylate is a synthetic molecule created by linking acrylic acid to a core called pentaerythritol, which has been partially modified with small units of polyethylene glycol (PEG) and polypropylene glycol (PPG). The result is a multi-functional acrylate that can form tough, clear films once it is cured with light or heat. Chemists first explored acrylates in the mid-20th century for industrial coatings. As nail polish technology moved from simple lacquer to longer-wear gel systems, this ingredient found a place because of its strength-building properties and reliable safety profile.

Manufacturing starts with pentaerythritol, a sugar alcohol obtained from petrochemical or plant-derived sources. This core is reacted with ethylene oxide to add PEG branches and propylene oxide to add PPG branches. Finally it is esterified with acrylic acid, giving each branch a reactive acrylate group. The resulting liquid resin is purified to remove unreacted monomers, filtered and packaged for cosmetic labs.

You will most often see Peg-4/Ppg-1 Pentaerythrityl Tetraacrylate in gel nail polishes, brush-on builder gels, UV-curable top coats and some nail strengtheners. Its ability to form hard glossy films in a matter of minutes makes it less common in skin care or hair products, where flexibility is more important.

Peg-4/Ppg-1 Pentaerythrityl Tetraacrylate’s Cosmetic Benefits/Uses

In nail products this ingredient serves one main purpose that makes manicures last longer and look better.

Nail conditioning: Once cured the acrylate network reinforces the natural nail plate, helping resist chips, splits and everyday wear. It also locks in shine so color stays vibrant throughout the life of the manicure.

Who Can Use Peg-4/Ppg-1 Pentaerythrityl Tetraacrylate

This ingredient is generally considered suitable for all skin types because it stays on the nail plate not the skin once it is cured. Even sensitive or acne-prone users typically tolerate it well since it is noncomedogenic and forms an inert film after hardening. People with a known acrylate allergy, however, should avoid it as even brief contact with the uncured resin can trigger a reaction.

The molecule is fully synthetic and contains no animal-derived components or by-products so it is compatible with vegan and vegetarian lifestyles.

No data indicate that properly cured Peg-4/Ppg-1 Pentaerythrityl Tetraacrylate penetrates the nail bed or enters the bloodstream. Because exposure is minimal pregnant or breastfeeding individuals can generally use nail products containing it, but this is not medical advice and anyone expecting or nursing should review any cosmetic routine with a qualified health professional first.

The cured film does not make skin or nails more sensitive to sunlight and the ingredient itself is not photo-reactive, so photosensitivity is not a concern. One extra note: professional or at-home gel systems that use this acrylate require a UV or LED lamp; users should follow lamp-use guidelines to protect surrounding skin from excess UV exposure.

Potential Side Effects/Adverse Reactions

Responses to topical Peg-4/Ppg-1 Pentaerythrityl Tetraacrylate differ from person to person. The issues listed below represent potential side effects that might occur even though most people will experience none when the ingredient is formulated and used correctly.

  • Allergic contact dermatitis including redness itching or swelling where uncured resin touches the skin
  • Mild irritation or burning sensation if the liquid accidentally contacts cuticles or surrounding skin before curing
  • Eye irritation and watering if the uncured product splashes into the eyes
  • Respiratory sensitivity such as coughing or throat irritation from inhaling filing dust created when hardened gel is mechanically removed
  • Brittleness or thinning of the natural nail plate if products are over-cured or removed aggressively

If any adverse reaction occurs stop using the product immediately remove it following manufacturer directions and consult a healthcare professional.

Comedogenic Rating

Rating: 0/5 Peg-4/Ppg-1 Pentaerythrityl Tetraacrylate is a large, cross-linking resin that sets into a hard film on the nail rather than remaining on skin. It contains no heavy oils or waxes that could clog pores and its molecular size prevents it from migrating into follicles. For these reasons it is considered non-comedogenic and is suitable for people prone to acne or breakouts. Because the ingredient is cured and then filed off rather than left to sit on facial skin, the chance of pore blockage is practically nonexistent. The only time skin comes into contact with it is during application, when it is still liquid, and that contact is brief.

Summary

Peg-4/Ppg-1 Pentaerythrityl Tetraacrylate is used in nail products to create a tough, glossy film that strengthens the natural nail plate and locks in color. It achieves this by polymerizing its acrylate groups under UV or LED light, forming a dense network that resists chips and wear. Within the nail industry it is a staple in gel polishes and builder gels but it is rarely found in skin or hair formulas, so its popularity is high in salons yet low in the broader cosmetic aisle.

Overall safety is considered good when the resin is fully cured and removal is gentle. Sensitivity mostly centers on uncured product contact or aggressive filing. As with any new cosmetic, it is wise to do a quick patch test with the complete formula to rule out individual reactions.

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