Peg-45 Palm Kernel Glycerides: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Peg-45 Palm Kernel Glycerides?

Peg-45 Palm Kernel Glycerides is an ingredient made by attaching roughly 12 units of ethylene oxide to the natural mono- and diglycerides found in palm kernel oil. This process, called ethoxylation, turns the oil-based molecules into water-loving ones, creating a versatile substance that blends oil and water with ease. Manufacturers began exploring ethoxylated palm kernel derivatives in the late 1970s as a plant-based alternative to animal fats and petroleum-derived surfactants, and the ingredient quickly gained popularity in skin care and hair care formulas.

Production starts with sustainably sourced palm kernels that are pressed to obtain crude oil. The oil is split into glycerides, then partially hydrolyzed to free up mono- and diglycerides. These are reacted with ethylene oxide under controlled heat and pressure. The result is a creamy, wax-like material that melts easily into cosmetic bases and offers reliable performance across a wide pH range.

You will most often spot Peg-45 Palm Kernel Glycerides in moisturizers, lotions, facial masks, sunscreens, cleansing balms, leave-on hair conditioners and styling creams. Formulators value it for giving products a smooth, non-greasy finish and helping actives stay evenly dispersed from the first pump to the last.

Peg-45 Palm Kernel Glycerides’s Cosmetic Benefits/Uses

Peg-45 Palm Kernel Glycerides mainly serves one important purpose in cosmetics.

Emulsifying: It helps oil and water combine into a stable, uniform mixture, preventing separation over time. This ensures creams feel silky, rinses stay homogeneous and active ingredients remain evenly distributed so every application delivers consistent results.

Who Can Use Peg-45 Palm Kernel Glycerides

Peg-45 Palm Kernel Glycerides tends to play nicely with most skin types, including dry, normal and combination skin, because it sits lightly on the surface and does not add heavy occlusive residue. Oily and acne-prone users usually tolerate it as well, though very sensitive or reactive skin may want to monitor for any signs of irritation simply because every skin barrier is different. The ingredient itself is nonionic and has no known triggers for rosacea, eczema or psoriasis when used in low to moderate amounts.

Because it is derived from palm kernel oil, not animal sources, Peg-45 Palm Kernel Glycerides is suitable for vegans and vegetarians. Brands that are certified cruelty-free often choose it as a plant-based alternative to emulsifiers made with animal fats.

Current data does not flag this ingredient as unsafe for women who are pregnant or breastfeeding when applied topically. Still, this is not medical advice and anyone who is expecting or nursing should run any skincare or haircare formula past a doctor to be on the safe side.

The molecule does not increase the skin’s sensitivity to sunlight, so it is not considered photosensitizing. It also plays well alongside most common actives such as retinoids, vitamin C and alpha hydroxy acids without destabilizing them, making it a flexible option in multi-step routines.

Potential Side Effects/Adverse Reactions

Side effects and reactions to topical Peg-45 Palm Kernel Glycerides can vary from person to person. The following is a list of potential issues only and they are unlikely to be the typical user experience as long as the ingredient is correctly formulated and used.

  • Mild skin irritation such as redness or itching
  • Stinging sensation on compromised or freshly exfoliated skin
  • Rare allergic contact dermatitis in individuals sensitive to polyethylene glycol compounds
  • Eye irritation if the product accidentally migrates into the eyes

If you experience any of these reactions discontinue use and consult a qualified healthcare professional.

Comedogenic Rating

Rating: 1/5 — The ethoxylation process makes Peg-45 Palm Kernel Glycerides far more water friendly than raw palm kernel oil, so it does not readily clog pores. It sits on the skin in a thin, dispersible layer that rinses away with normal cleansing which keeps the likelihood of trapped sebum low.

In most formulas this ingredient is used at small percentages, further reducing any pore-blocking risk. Overall it is considered suitable for people who are prone to acne or breakouts, though individual results can vary.

Formulas that pair it with very heavy oils or waxes could still feel greasy on oily skin, so the full ingredient list matters when judging any product.

Summary

Peg-45 Palm Kernel Glycerides is mainly an emulsifier that helps mix oil and water so lotions, creams and conditioners stay smooth from the first use to the last. Its plant origin, reliable performance over a wide pH range and ability to leave a light after-feel have made it a steady choice in skin care and hair care since the late 1970s, especially in mid-priced and natural-leaning brands.

Current safety data shows a low risk of irritation or sensitization when used as directed, and its comedogenic rating of 1 makes it friendly to most skin types. As with any new cosmetic ingredient it is smart to do a quick patch test when trying a fresh product to catch any personal sensitivities early.

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