Peg-5 Glyceryl Triisostearate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Peg-5 Glyceryl Triisostearate?

Peg-5 Glyceryl Triisostearate is a plant or vegetable derived ester that links glycerin, isostearic acid and a small chain of ethylene oxide units. The result is a waxy liquid that mixes well with both oils and water. First introduced in the late 1990s as a gentler alternative to traditional surfactants, it quickly found a place in skin care because it softens skin without feeling greasy.

The ingredient is produced through a two step process. First, natural isostearic acid—often sourced from rapeseed or soybean oil—is reacted with glycerin to form glyceryl triisostearate. Next, five units of ethylene oxide are added to create the PEG-5 segment, giving the molecule its partial water solubility. The finished material is purified, tested for residual impurities and then supplied as a clear to pale yellow liquid.

You will most often spot Peg-5 Glyceryl Triisostearate in cleansing balms, cream cleansers, makeup removers, moisturizing lotions, overnight masks and rich anti aging creams where a smooth, cushiony skin feel is desired.

Peg-5 Glyceryl Triisostearate’s Cosmetic Benefits/Uses

This ingredient plays two key roles in a formula

  • Emollient – fills in tiny gaps on the skin surface for an instantly smoother touch, reduces moisture loss and leaves a soft non sticky finish
  • Emulsifying – helps oil and water stay blended, keeping creams stable so they do not separate while also allowing cleansers to rinse away cleanly

Who Can Use Peg-5 Glyceryl Triisostearate

Peg-5 Glyceryl Triisostearate suits most skin types, including dry, normal and combination skin thanks to its softening nature and light feel. Sensitive skin generally tolerates it as well since it is considered mild, though anyone highly reactive to polyethylene glycols may want to proceed with care. Very oily or acne prone users rarely have trouble, yet those who break out easily might prefer lower concentrations to avoid a heavy after-feel.

The ingredient is typically plant derived and contains no animal by-products so it is usually appropriate for vegetarians and vegans. If this matters to you check with the brand to confirm its source and that no animal testing was involved.

Current safety data shows no specific hazards for pregnant or breastfeeding women when the ingredient is used as directed in topical products. This is not medical advice and anyone who is pregnant or nursing should show the full ingredient list of any product to a healthcare professional before use just to be safe.

Peg-5 Glyceryl Triisostearate does not make skin more sensitive to sunlight and it can be worn day or night without extra sun-related precautions.

Potential Side Effects/Adverse Reactions

Side effects and reactions to the topical application of Peg-5 Glyceryl Triisostearate can vary from person to person. The points below list potential issues only and most users will not experience them when the ingredient is used correctly in a well-formulated product.

  • Mild skin irritation such as redness or itching in those sensitive to polyethylene glycol derivatives
  • Allergic contact dermatitis in rare cases of individual allergy to isostearic acid or related fatty acids
  • Temporary eye stinging if a cleanser or balm containing the ingredient gets into the eyes
  • Clogged pores or small breakouts in very acne prone individuals when used at high levels or layered with rich occlusive products
  • Contamination-related reactions if the finished product is not preserved properly since the ingredient itself does not provide antimicrobial protection

If you notice any discomfort, rash or unusual reaction while using a product with Peg-5 Glyceryl Triisostearate stop use and consult a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 1 / 5

Peg-5 Glyceryl Triisostearate earns a low score because its bulky isostearic chains are less likely to pack tightly inside pores and the attached PEG pieces give it better rinse-off compared with straight fatty esters. It sits lightly on skin, adds slip without a heavy occlusive film and is usually used at modest levels which further lowers clogging risk.

Most people prone to acne or breakouts can use products containing this ingredient without major concern, though individual responses can vary.

Formula context matters: when combined with very rich butters or waxes the overall product could still feel weighty which may increase chances of congestion for some users.

Summary

Peg-5 Glyceryl Triisostearate works as an emollient and an emulsifier. The isostearic part smooths rough spots and reduces moisture loss while the short PEG chain helps oil and water stay blended so creams stay stable and cleansers rinse away easily.

It shows up most in cleansing balms, makeup removers, cream cleansers and a handful of rich lotions. It is useful but not a headline ingredient so you will see it less often than classics like glyceryl stearate or PEG-7 glyceryl cocoate.

Safety data labels it as low risk with only rare irritation or clogging issues reported. As with any new skincare ingredient it is wise to patch test a product before full use to make sure your skin agrees with it.

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