Peg-5 Pentaerythrityl Dimethylol Propionate-2 Dendrimer: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Peg-5 Pentaerythrityl Dimethylol Propionate-2 Dendrimer?

PEG-5 Pentaerythrityl Dimethylol Propionate-2 Dendrimer is a lab-crafted, highly branched polymer that starts with pentaerythritol, a simple sugar alcohol often sourced from plant sugars. Chemists first attach five units of ethylene oxide to create a short polyethylene glycol (PEG) chain, then build out two layers with dimethyl propionic acid. The result is a tree-like molecule called a dendrimer, prized for its tidy, uniform structure.

Dendrimers began attracting attention in the late 1990s for their ability to hold or bind other ingredients, which quickly led to trials in skin and hair care. This specific PEG-based dendrimer offered an appealing mix of water compatibility and film-forming power, so formulators started adding it to styling gels, setting sprays and long-wear makeup in the early 2000s.

Manufacturing involves controlled, stepwise reactions in stainless-steel reactors. Each layer is purified before the next is added, giving a consistent, cosmetic-grade ingredient with low impurity levels. Because it is made entirely in the lab, supply is stable year-round and free of animal-derived materials.

You will most often spot PEG-5 Pentaerythrityl Dimethylol Propionate-2 Dendrimer in hair sprays, mousses, curl creams, brow gels, long-lasting foundations, primers, sheet masks and certain oil-free moisturizers where lightweight hold or texture enhancement is desired.

Peg-5 Pentaerythrityl Dimethylol Propionate-2 Dendrimer’s Cosmetic Benefits/Uses

This multitasking dendrimer brings several practical perks to modern formulas

  • Absorbent – soaks up excess sebum or moisture, helping products feel less greasy and improving their staying power on skin or hair
  • Binding – helps powdered pigments or actives stick together evenly, giving smoother application and preventing separation in the jar
  • Emulsion Stabilising – keeps oil and water phases blended, extending shelf life and ensuring the texture stays uniform from first use to last
  • Film Forming – creates a flexible, invisible layer that locks in active ingredients, boosts water resistance and adds a soft-focus finish
  • Hair Fixing – delivers light to medium hold in styling products without the crunch or flaking some traditional resins can cause

Who Can Use Peg-5 Pentaerythrityl Dimethylol Propionate-2 Dendrimer

This dendrimer is generally considered friendly for all skin types. Its lightweight, non-occlusive film forms without trapping excess oil so oily and combination skins benefit from the extra staying power without extra shine. Normal and dry skins gain a soft protective layer that does not feel heavy. Even sensitive skin tends to tolerate it because the polymer has a large molecular size that limits deep penetration, though anyone with a history of reactions to PEGs should stay alert for irritation.

Because the ingredient is fully synthetic and contains no animal-derived substances, it is suitable for vegans and vegetarians.

No research flags the dendrimer as problematic during pregnancy or while breastfeeding. Still, this is not medical advice and anyone expecting or nursing should check with a doctor before introducing new products.

The molecule does not absorb UV light or make skin more reactive to sunlight so it is not considered photosensitising. It is also fragrance free and does not interfere with common active ingredients like retinoids or vitamin C, giving formulators wide latitude to pair it with other skin care staples.

Potential Side Effects/Adverse Reactions

Responses to topical Peg-5 Pentaerythrityl Dimethylol Propionate-2 Dendrimer vary from person to person. The issues listed below are possible but not probable for most users when the ingredient is properly formulated and used as directed.

  • Mild skin redness or stinging in individuals sensitive to polyethylene glycol derivatives
  • Contact dermatitis in rare cases of true allergy to the polymer or residual processing aids
  • Temporary eye irritation if hair sprays or mists drift into the eyes
  • Dry-feeling hair or skin when applied in very high concentrations without accompanying hydrators
  • Build-up on hair shafts leading to dullness if cleansing is inadequate between styling sessions

If any of these effects occur stop using the product and seek guidance from a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 1 out of 5. Peg-5 Pentaerythrityl Dimethylol Propionate-2 Dendrimer is a large, water-compatible polymer that sits on the surface rather than sinking deeply into pores. It forms a breathable film and does not add heavy oils or waxes that can trap sebum, so the risk of clogging is very low.

Suitable for acne-prone or breakout-prone skin in most formulations.

As with any film former, over-layering multiple products that all contain the ingredient can create build-up, which could indirectly contribute to congestion if cleansing is insufficient.

Summary

Peg-5 Pentaerythrityl Dimethylol Propionate-2 Dendrimer acts as an absorbent, binder, emulsion stabiliser, film former and hair-fixing agent. Its dendrimer structure offers many branching points that attract both water and oily components, letting it hold pigments, keep oil-water mixes uniform and lay down a thin flexible film that boosts wear time and light hold.

The ingredient enjoys steady although not blockbuster use in hair sprays, long-wear makeup and some oil-free moisturisers where lightweight hold and texture control are valued.

Current safety data classifies it as low risk for irritation or comedogenicity. Still, individual sensitivities vary, so it is wise to patch test any new product that lists Peg-5 Pentaerythrityl Dimethylol Propionate-2 Dendrimer near the top of the ingredient list before applying it more broadly.

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