Peg-65 Butylene Glycol Isostearate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Peg-65 Butylene Glycol Isostearate?

PEG-65 Butylene Glycol Isostearate is a specialty ingredient created by attaching roughly 65 units of ethylene oxide to butylene glycol that has been joined with isostearic acid, a fatty acid usually sourced from plant oils such as coconut or rapeseed. The result is a water-loving yet oil-compatible molecule that works well in many personal care formulas.

Chemists began exploring polyethylene glycol (PEG) derivatives in the mid-20th century as they searched for gentle alternatives to traditional soaps. PEG-65 Butylene Glycol Isostearate emerged as part of that wave, offering reliable cleansing power without the tight, squeaky feel older surfactants often caused. Its ability to mix oil and water also made it a handy tool for creating stable creams and lotions, so it quickly found a place in modern skincare labs.

The ingredient is produced through a controlled reaction where butylene glycol is first esterified with isostearic acid. Ethylene oxide is then added in multiple steps until the average chain length reaches 65 units. Each batch is carefully purified and tested to meet cosmetic safety standards.

Today you will spot PEG-65 Butylene Glycol Isostearate in facial cleansers, makeup removers, sheet masks, micellar waters, lightweight moisturizers, anti-aging serums and even some hair conditioners. Formulators like it because it boosts rinse-off performance while keeping textures silky and non-greasy.

Peg-65 Butylene Glycol Isostearate’s Cosmetic Benefits/Uses

This multitasker delivers two main benefits that help products look, feel and perform better on the skin.

  • Cleansing: Its surfactant nature lifts away excess oil, makeup and daily grime without stripping the skin’s natural moisture barrier, leaving the face feeling fresh and comfortable
  • Emulsifying: By bridging water and oil phases it stabilizes creams, lotions and cleansing milks, preventing separation and ensuring a smooth, even texture throughout a product’s shelf life

Who Can Use Peg-65 Butylene Glycol Isostearate

Because it is gentle and water soluble Peg-65 Butylene Glycol Isostearate is generally suitable for all skin types including dry, oily, combination and sensitive skin. It cleanses without aggressive foaming agents so it rarely leaves skin tight or irritated. Extremely reactive or eczema-prone skin may still prefer very simple formulas but most people tolerate this ingredient well.

The raw materials are usually sourced from plant oils and synthesized chemicals rather than animal by-products so finished formulas that feature this ingredient are commonly acceptable for vegans and vegetarians. If strict cruelty-free or plant-only status is important it is best to check with the brand about full supply chain details.

There is no specific data showing that Peg-65 Butylene Glycol Isostearate poses a risk to women who are pregnant or breastfeeding. Its large molecular size limits skin penetration and it is used at low levels in rinse-off and leave-on products. Still this is not medical advice and anyone who is pregnant or nursing should discuss all skincare choices with a qualified healthcare provider.

The ingredient does not increase the skin’s sensitivity to sunlight so it is not linked to photo-induced reactions. Users should of course keep wearing daily sunscreen to protect against UV damage in general.

Potential Side Effects/Adverse Reactions

Individual responses to topical Peg-65 Butylene Glycol Isostearate can vary. The following points describe potential side effects that might occur in rare cases. When the ingredient is properly formulated most users will not experience any problems.

  • Mild redness or stinging on very sensitive skin
  • Transient eye irritation if the product accidentally gets into the eyes
  • Allergic contact dermatitis in people with a specific PEG allergy
  • Occasional breakouts in users who react to any fatty ester even though the ingredient itself is considered low risk for clogging pores

If you notice persistent discomfort swelling or other unusual reactions stop using the product and consult a healthcare professional.

Comedogenic Rating

Rating: 1/5. Peg-65 Butylene Glycol Isostearate is highly water soluble and gets rinsed off easily, which means it is unlikely to sit in pores long enough to cause blockages. While it carries a fatty acid tail, the long PEG chain keeps the molecule light and non-greasy so the overall clogging risk stays very low.

Because of this low rating, the ingredient is generally considered suitable for people who are prone to acne or frequent breakouts. Those with extremely reactive skin should still pay attention to the full formula since other richer oils or waxes in the product could change the final pore-clogging potential.

Summary

Peg-65 Butylene Glycol Isostearate works as a gentle cleanser and a reliable emulsifier. The PEG side loves water while the isostearate side loves oil, helping it lift makeup and dirt off the skin then rinse away without leaving a film. That same split personality keeps creams and lotions from separating so textures stay smooth from the first pump to the last.

It is a quiet helper rather than a headline act. You will find it in many modern cleansers, micellar waters and lightweight moisturizers, but most shoppers never notice it on the label. Formulators pick it because it is dependable, easy to work with and kind to most skin types.

Safety studies and long years of use show a low risk of irritation or toxicity when used at normal cosmetic levels. Still everyone’s skin is different so it is smart to do a small patch test whenever you bring a new product into your routine.

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