Peg-9 Diglycidyl Ether/Sodium Hyaluronate Crosspolymer: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Peg-9 Diglycidyl Ether/Sodium Hyaluronate Crosspolymer?

Peg-9 Diglycidyl Ether/Sodium Hyaluronate Crosspolymer is a modern form of hyaluronic acid that has been chemically linked with a small polyethylene glycol (PEG-9) molecule. By crosslinking sodium hyaluronate with PEG-9 diglycidyl ether, chemists create a three-dimensional network that is more stable and longer-lasting on the skin than regular hyaluronic acid. The raw materials start with plant-derived glucose that is fermented to produce hyaluronic acid, while PEG-9 diglycidyl ether is synthesized from ethylene oxide. During manufacturing, the two ingredients are mixed in water under controlled pH and temperature, allowing the epoxy groups on PEG-9 to react with the hydroxyl groups on hyaluronic acid. Once purified and dried, the result is a flexible, water-loving powder or gel that swells in water and holds moisture.

The crosslinked version was first explored in the early 2000s as brands searched for ways to keep hyaluronic acid from washing away too quickly. Its success in medical wound dressings encouraged cosmetic formulators to adopt it for beauty products. Today you will find Peg-9 Diglycidyl Ether/Sodium Hyaluronate Crosspolymer in lightweight serums, sheet masks, anti-aging creams, long-wear moisturizers and after-sun treatments, anywhere a lasting moisture veil is desired.

Peg-9 Diglycidyl Ether/Sodium Hyaluronate Crosspolymer’s Cosmetic Benefits/Uses

In skin care formulas this ingredient serves one key purpose.

Skin conditioning: The crosslinked network traps large amounts of water, forming a breathable film that keeps skin hydrated for hours. This helps smooth fine lines caused by dryness, supports a plump fresh look and improves the glide of a product during application while leaving a non-sticky finish.

Who Can Use Peg-9 Diglycidyl Ether/Sodium Hyaluronate Crosspolymer

This ingredient suits almost every skin type, from very dry to oily and even sensitive, because it is lightweight, oil free and non occlusive. Its water binding film prevents dehydration without clogging pores, so acne-prone users can generally enjoy it as well. The raw hyaluronic acid is produced through microbial fermentation and the PEG component is synthetically derived, meaning no animal material is involved, making it appropriate for vegans and vegetarians.

Current research and cosmetic safety assessments show no specific risks for women who are pregnant or breastfeeding when the ingredient is used topically, as its large crosslinked structure stays on the surface of skin rather than entering the bloodstream. This is not medical advice; anyone who is pregnant or nursing should have a doctor review all skincare products first to be safe.

Peg-9 Diglycidyl Ether/Sodium Hyaluronate Crosspolymer does not make skin more sensitive to sunlight and can be worn day or night without increasing the need for sun protection. It layers well under sunscreen and makeup, functions in both humid and arid climates and plays nicely alongside exfoliating acids, retinoids or vitamin C without interfering with their activity.

Potential Side Effects/Adverse Reactions

Responses to topical Peg-9 Diglycidyl Ether/Sodium Hyaluronate Crosspolymer vary from person to person. The points below outline potential, but unlikely, side effects when the ingredient is used at appropriate cosmetic levels.

  • Mild redness or flushing
  • Temporary itching or tingling sensation
  • Localized irritation if the finished formula contains residual solvent or a low pH system
  • Rare allergic contact dermatitis triggered by sensitivity to the PEG portion
  • Puffiness or swelling in individuals already prone to fluid retention around the eyes

If any of these reactions occur stop using the product and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 0/5 (non comedogenic) This crosslinked hyaluronic acid is water loving not oil based, forms a breathable film that stays on the surface and has no fatty components that could block pores so it is highly unlikely to trigger blackheads or breakouts.

Yes, it is suitable for skin that is prone to acne or frequent blemishes.

Its presence is typically at low levels in lightweight gels or serums meaning the overall likelihood of a finished product causing congestion depends more on the other ingredients rather than this polymer itself.

Summary

Peg-9 Diglycidyl Ether/Sodium Hyaluronate Crosspolymer acts as a potent skin conditioner by locking water into a flexible three-dimensional network that keeps skin hydrated smooth and comfortably plump for hours. This enhanced moisture retention also gives products a silky glide and helps soften the look of fine dryness lines.

While it has a lower profile than traditional hyaluronic acid its reputation is growing in modern serums masks and long wear moisturizers where lasting hydration is a selling point.

Safety reviews show it is generally very gentle with a low risk of irritation sensitization or pore clogging making it a dependable choice for most users. Still it is wise to perform a simple patch test anytime you introduce a new formula that features this or any other novel ingredient.

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