Phosphorylcholine Glycol Methacrylate/Peg-10 Dimethacrylate Crosspolymer: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Phosphorylcholine Glycol Methacrylate/Peg-10 Dimethacrylate Crosspolymer?

Phosphorylcholine Glycol Methacrylate/Peg-10 Dimethacrylate Crosspolymer is a lab-created network of two building blocks: phosphorylcholine glycol methacrylate, which mimics the hydrating head of skin-friendly phospholipids, and PEG-10 dimethacrylate, a flexible linking agent derived from polyethylene glycol. When chemists polymerize these two monomers, they form a stable mesh that swells with water and hugs the skin in a light, breathable film.

The idea of borrowing phosphorylcholine from biomedical materials sparked interest in the early 2000s. Because this group is known for its biocompatibility in contact lenses and drug delivery, formulators wondered if a similar structure could improve skin feel in cosmetics. By tweaking the ratio of the two monomers, they created a crosspolymer that adds slip, locks in moisture and resists breakdown in the jar.

Manufacturing starts with purified monomers that are mixed, then activated with heat or light so they join into long chains. Cross-linking agents tie those chains together, creating a three-dimensional network. The finished powder is washed, dried and milled before it goes into creams, lotions, sheet mask essences, hydrating primers, anti-aging serums, after-sun gels and makeup formulas that need a smooth long-lasting finish.

Phosphorylcholine Glycol Methacrylate/Peg-10 Dimethacrylate Crosspolymer’s Cosmetic Benefits/Uses

This ingredient pulls triple duty in skin care and makeup formulas.

  • Film forming: Creates an invisible flexible layer that helps active ingredients stay put, boosts water resistance in makeup and leaves a silky touch rather than a sticky feel
  • Humectant: Attracts and holds water from the environment and deeper skin layers, giving an instant plump look and reducing the appearance of fine lines caused by dehydration
  • Skin conditioning: Softens and smooths rough areas so skin feels comfortable and makeup glides on more evenly

Who Can Use Phosphorylcholine Glycol Methacrylate/Peg-10 Dimethacrylate Crosspolymer

The lightweight water-binding film this polymer creates makes it friendly for almost every skin type. Dry and dehydrated skin benefit from its humectant action, oily or acne-prone skin appreciate that it is non-greasy and does not clog pores, while sensitive skin generally tolerates the inert polymer network thanks to its large molecular size and low penetration. People with a proven allergy to acrylate or methacrylate materials should avoid it as a precaution.

The ingredient is entirely synthetic and contains no animal-derived raw materials, so it aligns with vegan and vegetarian lifestyles provided the finished product is certified cruelty free by the brand.

There is no evidence that the polymer poses a risk to women who are pregnant or breastfeeding because its large crosslinked structure prevents absorption through intact skin. This is not medical advice; expectant or nursing mothers should still show any skincare routine to their physician for individual guidance.

The polymer does not make skin more sensitive to sunlight and can be used in both daytime and nighttime products without increasing the need for sun protection beyond the usual SPF recommendation.

Potential Side Effects/Adverse Reactions

Responses to topical Phosphorylcholine Glycol Methacrylate/Peg-10 Dimethacrylate Crosspolymer vary from person to person. The issues listed below are possible yet uncommon when the ingredient is formulated correctly and used as directed.

  • Mild redness or stinging in very reactive or compromised skin
  • Contact dermatitis in individuals already sensitized to acrylate or methacrylate chemistry
  • Watery eyes or transient eye irritation if a product containing the polymer migrates into the ocular area
  • A temporary tight or dry sensation when applied in formulas with a high percentage of film former

If you notice any of these reactions discontinue use and consult a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 0 (non-comedogenic)

The crosspolymer is a bulky water-loving molecule that stays on the skin surface rather than settling inside pores. It contributes no oils or waxes that could trap dead cells or sebum, and it is easily removed with normal cleansing. For these reasons it earns the lowest possible score on the comedogenic scale.

This makes the ingredient generally suitable for people who are prone to acne or frequent breakouts.

If a formula pairs the polymer with heavy occlusive oils or butters, pore-clogging potential will depend on those co-ingredients rather than on the polymer itself.

Summary

Phosphorylcholine Glycol Methacrylate/Peg-10 Dimethacrylate Crosspolymer is valued for three main jobs: it forms a flexible film that holds active ingredients in place, it acts as a humectant by drawing moisture to the skin, and it conditions the surface for a smoother feel. Its crosslinked network swells with water, creating a light breathable layer that locks in hydration and enhances the slip of creams, gels and makeup.

While not as well known as hyaluronic acid or glycerin, the polymer has carved out a quiet niche in hydrating primers, sheet mask serums and long-wear cosmetics where a weightless non-sticky finish is a selling point.

Current research and practical experience show it to be low risk for irritation or sensitization thanks to its large non-penetrating structure, yet it is always wise to patch test any new product to confirm personal compatibility.

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