Phytosphingosine Lactate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Phytosphingosine Lactate?

Phytosphingosine lactate is a salt formed when phytosphingosine, a skin-identical lipid, pairs with lactic acid. Phytosphingosine itself is a long-chain amino alcohol that naturally occurs in the outer layer of human skin as well as in some plant oils and yeast. By joining it with lactic acid, chemists create a more water-friendly version that is easier to add to creams and lotions.

The cosmetic world became interested in phytosphingosine in the late 1990s after studies showed its key role in keeping the skin barrier strong. Turning it into the lactate form gave formulators a stable, gentle ingredient that could deliver those benefits in everyday products.

Manufacturing usually starts with plant-derived oils rich in sphingolipids. Through controlled fermentation and purification steps, phytosphingosine is separated, then reacted with food-grade lactic acid to form the final salt. The result is a fine powder or clear solution that blends well with water-based or oil-based formulas.

You’ll most often spot phytosphingosine lactate in moisturizers, calming serums, anti-aging creams, aftershave balms, sheet masks and leave-on treatments made for sensitive or dry skin.

Phytosphingosine Lactate’s Cosmetic Benefits/Uses

In skincare formulas phytosphingosine lactate serves one key purpose that brings several practical benefits.

As a skin conditioning agent it helps reinforce the skin’s natural barrier, leading to better moisture retention and a smoother feel. Regular use can make skin look healthier, feel softer and become less prone to redness or tightness caused by dryness.

Who Can Use Phytosphingosine Lactate

Phytosphingosine lactate is generally suitable for all skin types including dry, sensitive, oily and mature skin since it mimics lipids already found in the skin and helps strengthen the barrier without leaving a greasy residue. People prone to redness or tightness often appreciate its calming feel. It is not known to clog pores so even acne-prone users can usually tolerate it well. Those with a confirmed allergy to lactic acid or sphingolipids should avoid it, otherwise there are no specific skin type exclusions.

The ingredient is produced from plant-derived oils and fermented lactic acid so it is considered vegan and vegetarian friendly. No animal derivatives or animal testing are required for its manufacture.

Current research has not flagged any special risks for pregnant or breastfeeding women when using phytosphingosine lactate in normal cosmetic concentrations. This information is not medical advice and anyone who is pregnant or nursing should ask a healthcare provider before adding new skincare products just to be safe.

Phytosphingosine lactate does not make skin more sensitive to sunlight and can be used morning or night without raising the risk of sunburn. Standard daily sunscreen is still recommended for overall skin health.

Potential Side Effects/Adverse Reactions

Responses to topical phytosphingosine lactate differ from person to person. The points below list potential side effects although most users experience none when the ingredient is correctly formulated and used as directed.

  • Mild tingling or stinging on application
  • Temporary redness or warmth
  • Dry patches if layered with strong exfoliants or retinoids
  • Allergic contact dermatitis in individuals sensitive to sphingolipids or lactic acid

If any of these reactions occur stop using the product and seek advice from a healthcare professional.

Comedogenic Rating

Rating: 0–1 (practically non-comedogenic)

Phytosphingosine lactate is a skin-identical lipid used at low concentrations and has a lightweight, non-occlusive texture. It integrates into the skin barrier rather than sitting on top of pores so it is highly unlikely to trap oil or debris. Because of this it earns a score at the very bottom of the scale.

Suitable for acne-prone or breakout-prone skin.

No published data link this ingredient to an increase in blackheads or pimples, even in leave-on formulas.

Summary

Phytosphingosine lactate conditions skin by reinforcing the natural lipid barrier, which improves moisture retention and reduces dryness-related redness. It does this by slotting into the stratum corneum where its lipid structure helps seal in water while lactic acid keeps the molecule water-compatible so it spreads evenly in creams and serums.

Although not a headline act like hyaluronic acid or retinol, this ingredient is quietly popular in sensitive skin moisturizers, soothing serums and post-shave balms because it delivers comfort without heaviness.

Overall safety is excellent with a very low risk of irritation or clogged pores. As with any new skincare product, try a small patch first to make sure it agrees with your skin.

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