What Is Placental Protein?
Placental protein is an extract derived from the placenta of mammals, usually pigs or sheep that are processed for the food industry. After delivery the placental tissue is collected, thoroughly screened for safety, then subjected to gentle extraction methods that draw out its naturally occurring proteins along with small amounts of lipids, carbohydrates, nucleic acids and minerals. The resulting liquid or powder concentrate carries a broad mix of amino acids and peptides that help bind water, which is why it interests cosmetic chemists.
Interest in placenta began in the 1950s when beauty brands were searching for new anti-aging actives. Early spa treatments promoted “placenta facials,” and over time laboratory refinement removed much of the original scent and variability so formulators could add the ingredient to modern products. Today most cosmetic-grade placental protein is produced through enzymatic hydrolysis that breaks large proteins into smaller, skin-friendly fragments, followed by ultrafiltration and heat or irradiation steps that ensure microbiological safety.
You will commonly find placental protein in sheet masks, anti-aging serums, rich moisturizers, eye creams, leave-on hair conditioners and specialty ampoules aimed at boosting hydration and softness.
Placental Protein’s Cosmetic Benefits/Uses
In skin and hair care formulas placental protein serves primarily as a humectant, meaning it attracts and retains water. By drawing moisture from the environment and holding it at the surface, it helps replenish dehydrated skin, improves elasticity, softens the feel of dry patches and can give hair a smoother, glossier appearance.
Who Can Use Placental Protein
Placental protein is generally suitable for normal, dry, combination and mature skin because its humectant action helps all of these types hold extra moisture. Oily or acne-prone skin can also benefit, though very sensitive or reactive complexions might prefer lighter hydrators if rich, protein-based formulas feel heavy or clogging.
This ingredient is animal derived so it does not meet vegan or strict vegetarian standards. Even when sourced ethically as a by-product of the food industry, the raw material still comes from mammalian tissue and therefore falls outside plant-based criteria.
Pregnant or breastfeeding individuals can usually use topical products containing placental protein but data is limited. This information is not medical advice and anyone expecting or nursing should ask a healthcare professional before adding new skincare to be safe.
The ingredient is not known to increase photosensitivity, so it will not make skin more vulnerable to sunburn. Regular daytime sun protection is still important for overall skin health.
Potential Side Effects/Adverse Reactions
Responses to topical placental protein vary from person to person. The points below outline potential, though uncommon, effects when the ingredient is used in properly formulated cosmetic products.
- Allergic contact dermatitis
- Redness or stinging on very sensitive skin
- Clogged pores or breakouts if used in a heavy, occlusive formula
- Rare microbial contamination issues if manufacturing standards are poor
- Unwanted odor in older products as proteins degrade
If irritation or any other negative reaction occurs discontinue use immediately and consult a qualified healthcare provider.
Comedogenic Rating
Rating: 1/5. Placental protein is water soluble and low in oil, so it seldom blocks pores. Reports of congestion usually trace back to heavy creams or balms that happen to include the extract rather than the ingredient itself.
Most acne-prone users can tolerate placental protein provided the overall formula is lightweight and labeled non-comedogenic.
Because the extract is often delivered in glycerin or other low-clog carriers, risk remains minimal unless paired with thicker occlusives.
Summary
Placental protein works primarily as a humectant, drawing and holding water with its mix of amino acids and peptides to leave skin or hair plump soft and elastic. This moisture magnet effect makes it useful in masks serums conditioners and other leave-on products.
The ingredient had a surge of popularity in mid-century spa treatments and still pops up in certain K-beauty and boutique lines, though it is not as common as plant-based hydrators.
Topically it is considered low risk with few irritation reports and no photo-sensitizing issues, but it is always wise to patch test any new product that contains placental protein to be sure your skin tolerates it.