Poloxamine 1102: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Poloxamine 1102?

Poloxamine 1102 is a synthetic ingredient created by linking together small molecules of ethylene oxide and propylene oxide around a central nitrogen-containing core. The result is a block copolymer that behaves a bit like a molecular bridge, letting oil and water mix when they normally would not. It does not come from a natural plant or animal source; instead it is manufactured in controlled laboratory settings where the size of the polymer chain can be adjusted for specific performance needs.

The compound was first explored in the 1960s when chemists were looking for new surfactants that could be gentler on skin than traditional soaps. Its ability to stabilize mixtures quickly caught the eye of cosmetic formulators who needed reliable emulsifiers for creams and lotions. Today the ingredient is produced by carefully reacting propylene oxide with a starter molecule, then adding ethylene oxide in a set sequence. The process is monitored for temperature and pH to ensure a consistent final polymer.

You can find Poloxamine 1102 in a wide range of personal care items. It is common in lightweight facial moisturizers, rinse-off masks, leave-on serums, after-sun gels and some eye creams where a smooth, non-greasy texture is important. It also shows up in cleansing balms and makeup removers that need to wash away both water-based and oil-based residues.

Poloxamine 1102’s Cosmetic Benefits/Uses

In everyday skincare formulas Poloxamine 1102 serves one main purpose: it works as an emulsifying agent. By helping oil and water stay blended it keeps creams from separating, improves the spreadability of a product and ensures that active ingredients are delivered evenly across the skin. A stable emulsion also feels smoother on application and has a longer shelf life, which means the product you buy stays effective until the last use.

Who Can Use Poloxamine 1102

Poloxamine 1102 is generally considered suitable for all skin types. Dry skin benefits from its ability to keep water and oil evenly mixed in moisturizers while oily or combination skin appreciates the lightweight feel that does not add extra grease. Sensitive skin typically tolerates it well since the polymer is nonionic and has a low potential for irritation when properly formulated.

The ingredient is fully synthetic and contains no animal-derived components so products using Poloxamine 1102 are compatible with vegan and vegetarian lifestyles.

Current safety data shows no specific risks for pregnant or breastfeeding women when the ingredient is used topically in cosmetic concentrations. This information is provided for general knowledge only and does not replace medical advice; anyone who is pregnant or nursing should show any skincare routine to a qualified healthcare provider before use just to be safe.

Poloxamine 1102 does not increase photosensitivity and has no known interactions with sunlight. It also has a negligible comedogenic profile so it is unlikely to clog pores when used in leave-on products.

Potential Side Effects/Adverse Reactions

Individual responses to topical Poloxamine 1102 can vary. The points below outline potential side effects that have been reported although they are uncommon in well-formulated products.

  • Mild skin irritation a transient feeling of tightness or itching that usually subsides after the product is rinsed or removed
  • Allergic contact dermatitis localized redness or rash in people who are sensitized to the polymer or other ingredients in the same formula
  • Stinging on compromised skin a slight burn or sting if applied to abraded or freshly exfoliated areas
  • Eye irritation tearing or redness if the product accidentally gets into the eyes especially in high-rinse cleansers
  • Dryness when overused possible disruption of the skin’s lipid balance if combined with several other surfactants in a single routine

If any adverse reaction occurs stop using the product immediately and seek guidance from a healthcare professional.

Comedogenic Rating

Rating: 0 / 5

Poloxamine 1102 has an extremely low tendency to block pores because its large, water-loving structure keeps it mostly on the surface of the skin and allows easy rinse-off. It does not form a heavy, occlusive film and it lacks fatty acids that typically feed acne-causing bacteria.

Suitable for acne-prone or breakout-prone skin.

Because it is usually used at low concentrations and often in rinse-off or light leave-on formulas, the already minimal risk of congestion is further reduced.

Summary

Poloxamine 1102 is a lab-made emulsifier that keeps oil and water blended so creams stay smooth, feel light and deliver actives evenly. It does this by positioning its water-friendly and oil-friendly blocks between the two phases, stabilizing the mix and stopping separation.

You will spot it in a fair number of modern moisturizers, cleansers and makeup removers, though it is more of a behind-the-scenes workhorse than a buzzworthy hero ingredient.

Current research finds it safe for topical use across skin types with a very low risk of irritation or pore clogging. As with any new skincare product, it is smart to patch test first to check individual tolerance.

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