Polyanthranilic Acid Sulfate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polyanthranilic Acid Sulfate?

Polyanthranilic Acid Sulfate is a lab-created polymer that forms when anthranilic acid units are chemically linked together and then treated with sulfate groups. The resulting material is water-dispersible, giving formulators an easy way to add it to creams, lotions and rinses. Although its name sounds new, the base building block, anthranilic acid, has been studied since the early 1900s for its stable ring structure and natural antioxidant traits. Researchers later discovered that turning it into a polymer and adding sulfate groups enhanced its stability and surface activity, which opened the door for cosmetic use in the late 2010s.

Production starts with purified anthranilic acid, which undergoes controlled oxidative coupling to create long chains. These chains are then reacted with sulfuric acid to attach sulfate groups that improve water compatibility and skin feel. The finished powder is dried, milled and quality-checked before shipment to cosmetic labs.

Today you will most often see Polyanthranilic Acid Sulfate in sheet masks, lightweight serums, leave-on anti-aging creams, scalp tonics and clarifying cleansers where brands want added protection against microbes and daily environmental stress.

Polyanthranilic Acid Sulfate’s Cosmetic Benefits/Uses

Formulators reach for this ingredient because it can play more than one helpful role in a single product.

  • Antimicrobial: The polymer’s surface carries a mild positive charge that can disrupt the outer layers of common bacteria and yeasts, helping products stay fresh longer and supporting cleaner skin
  • Antioxidant: Its ring-rich backbone donates electrons to neutralize free radicals produced by sun exposure or pollution, which can help slow the look of fine lines and dullness

Who Can Use Polyanthranilic Acid Sulfate

This polymer is generally well suited to most skin types, including oily, combination, normal and dry skin. Its water-friendly structure lets it sit lightly on the surface without leaving a greasy film, which makes it comfortable for acne-prone and sensitive complexions too. Those with very reactive or compromised skin should still monitor how their skin feels, as with any new ingredient, but no special exclusions are known.

Polyanthranilic Acid Sulfate is synthesized entirely from lab materials and contains no animal-derived components, so it aligns with vegan and vegetarian lifestyles.

Current data shows no direct concerns for pregnant or breastfeeding women at the concentrations used in cosmetics. That said this information is not medical advice and anyone who is pregnant or nursing should review new skincare products with a doctor before use to be safe.

The ingredient does not increase sun sensitivity, so it can be worn during daytime routines without extra risk of sunburn. Normal daily sunscreen habits are still encouraged to guard against UV damage.

Potential Side Effects/Adverse Reactions

Responses to topical Polyanthranilic Acid Sulfate vary from person to person. The following list covers potential side effects yet these outcomes are uncommon when products are formulated and used as directed.

  • Mild stinging or warmth on application: usually subsides within minutes as the formula dries
  • Temporary redness or flushing: more likely if skin is already irritated from exfoliants or harsh weather
  • Dry or tight feeling: may appear in formulas with high percentages or low added moisturizers
  • Contact dermatitis: very rare but possible in individuals with a specific sensitivity to aromatic acids or sulfates
  • Interaction with leave-on acids or retinoids: layering multiple active products might heighten irritation in sensitive users

If any discomfort, rash or swelling develops stop use and seek guidance from a healthcare professional

Comedogenic Rating

Rating: 1/5

Polyanthranilic Acid Sulfate is water based, free of heavy oils and lacks waxy fillers that typically block pores. Its large polymer chains sit lightly on the skin surface then rinse away or break down through normal wear, so it rarely builds up inside follicles.

This low score makes the ingredient a comfortable option for people who are prone to acne or frequent breakouts.

No studies have linked the polymer to pore clogging even in complex formulas, but remember the finished product’s overall oil and wax content will still dictate how it behaves on very oily skin.

Summary

Polyanthranilic Acid Sulfate delivers two core benefits: it curbs microbial growth by disrupting cell walls and it scavenges free radicals thanks to its stable aromatic rings. Together these actions help keep products fresh and support skin looking calm and resilient.

Because the polymer is fairly new you will mainly spot it in innovative niche launches rather than long-standing classics, yet its multifunctional nature is drawing wider industry interest each year.

Available safety data points to a low irritation profile and minimal pore clogging risk, so the ingredient is considered safe for most users. Still, try a quick patch test with any new formula to make sure your own skin responds well.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search