Polyglyceryl-10 Diisostearate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polyglyceryl-10 Diisostearate?

Polyglyceryl-10 Diisostearate is a plant-derived emulsifier made by linking ten glycerin units together, then attaching two molecules of isostearic acid, a fatty acid usually sourced from vegetable oils like coconut or rapeseed. The result is a mild, biodegradable ingredient that can help oil and water mix. Polyglycerol esters first appeared in food in the 1950s and later moved into skin care when brands began looking for gentle alternatives to synthetic surfactants. Production starts with heating glycerin so its molecules join into a short chain, a step called polymerization. This polyglycerin is then reacted with purified isostearic acid to form the final ester. You will spot Polyglyceryl-10 Diisostearate in moisturizers, sunscreens, cleansing balms, makeup removers, BB creams, masks and many natural or sensitive-skin formulas thanks to its ability to keep textures smooth and stable.

Polyglyceryl-10 Diisostearate’s Cosmetic Benefits/Uses

In formulas this ingredient serves one main role that brings several practical benefits.

Emulsifying: It binds water and oil so creams stay uniform, feel lighter, absorb evenly and resist separating during shelf life or daily use. A well-emulsified product also helps active ingredients spread more evenly across the skin for consistent performance.

Who Can Use Polyglyceryl-10 Diisostearate

This emulsifier is generally suited to all skin types including dry, oily, combination and sensitive because it is mild nonionic and free of common irritants like fragrances or added solvents. Its lightweight fatty acid tails give slip without creating a heavy occlusive film so even acne-prone users tend to tolerate it well.

Because the glycerin backbone and isostearic acid are sourced from plants, products relying on Polyglyceryl-10 Diisostearate can fit vegan and vegetarian lifestyles provided the rest of the formula also avoids animal-derived materials.

The ingredient is considered low risk for women who are pregnant or breastfeeding. It is not absorbed in meaningful amounts and has no known hormonal activity, yet this is not medical advice and anyone expecting or nursing should show any new skincare product to a qualified healthcare professional before use.

Polyglyceryl-10 Diisostearate does not increase photosensitivity, so it will not make skin more prone to sunburn. Aside from its role as a gentle emulsifier there are no other notable usage caveats.

Potential Side Effects/Adverse Reactions

Responses to topical Polyglyceryl-10 Diisostearate vary from person to person. The points below outline potential reactions only and they are unlikely for most users when the ingredient is properly formulated and used as directed.

  • Mild skin irritation or transient redness – usually due to very sensitive skin or high usage levels in a formula
  • Allergic contact dermatitis – rare but possible if someone develops a sensitivity to the ester or to other ingredients in the same product
  • Eye stinging or watering – can occur if a cleanser or balm containing the ingredient accidentally gets into the eyes
  • Breakouts in extremely clog-prone skin – uncommon yet possible when the ingredient is blended into a very rich or greasy base

If any of these reactions occur stop using the product and consult a healthcare provider if symptoms persist or worsen.

Comedogenic Rating

Rating: 1 / 5 (very low)

The glycerin backbone of Polyglyceryl-10 Diisostearate is water loving and non-occlusive while its two branched isostearic acid tails do not pack tightly inside pores. This loose shape keeps the molecule from hardening in follicles so it rarely triggers congestion.

Most acne-prone users can use products containing this emulsifier without issues although overall pore friendliness still depends on the other oils and butters in the final formula.

Very high use levels or pairing it with heavy comedogenic ingredients could raise its clogging potential but on its own the risk stays minimal.

Summary

Polyglyceryl-10 Diisostearate is a plant based emulsifier that helps oil and water stay mixed stabilises textures and improves spreadability. It pulls this off by combining ten water loving glycerin units with two oil loving isostearic acid arms forming an effective bridge between both phases.

The ingredient is a quiet workhorse rather than a trend star yet its mildness and biodegradable profile keep it popular in natural sensitive skin and baby care lines with usage slowly increasing as brands swap out harsher surfactants.

Current data shows it is low in irritation toxicity and pore clogging so it is considered safe for everyday use. Still try a quick patch test when you pick up a new product just to make sure your skin agrees with the full formula.

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