Polyglyceryl-10 Dipalmitate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polyglyceryl-10 Dipalmitate?

Polyglyceryl-10 Dipalmitate is a plant-derived ingredient made by joining ten glycerin units together, then attaching two palmitic acid chains that usually come from palm or coconut oil. The result is a soft, waxy material that mixes well with both water and oils.

Interest in this compound grew as brands looked for gentle alternatives to petroleum-based emulsifiers. By the early 2000s formulators found that longer polyglycerin chains like “-10” offered reliable performance while still fitting into the trend toward more naturally sourced ingredients.

The manufacturing process starts with food-grade glycerin that is heated under vacuum to form polyglycerin-10. This backbone is then reacted with refined palmitic acid to create the final ester. The method keeps the ingredient mild, free of ethoxylation steps and suitable for sensitive-skin formulas.

You will spot Polyglyceryl-10 Dipalmitate in moisturizers, lightweight lotions, creams, cleansing balms, makeup removers, sheet masks, baby care products, sunscreens and some solid balm sticks that need a smooth glide.

Polyglyceryl-10 Dipalmitate’s Cosmetic Benefits/Uses

In a formula this multitasker mainly acts in two ways

  • Emollient – softens and smooths the skin surface so a product feels rich without leaving a greasy film
  • Emulsifying – helps water and oil mix into a stable cream or lotion which means the texture stays even and the active ingredients are delivered more consistently

Who Can Use Polyglyceryl-10 Dipalmitate

This ingredient is gentle enough for most skin types. Dry and normal skin benefit from its smoothing feel while combination and oily skin usually appreciate that it leaves little residue. Sensitive skin often tolerates it well since it is free of fragrances and harsh solvents. Those with very acne-prone skin should note that palmitic acid derivatives can occasionally clog pores in some people, though the risk is low when used at typical levels.

Polyglyceryl-10 Dipalmitate is sourced from plant glycerin and plant fats so it fits vegan and vegetarian lifestyles. No animal by-products are involved in its manufacture and it is not animal tested by most suppliers that follow modern cosmetic regulations.

There is no evidence that the ingredient poses a special risk to women who are pregnant or breastfeeding. Still, this is not medical advice and anyone expecting or nursing should check new products with a healthcare professional.

The molecule does not make skin more sensitive to sunlight and can be used day or night without raising the chance of sunburn. It also plays well with common actives like vitamin C, niacinamide and retinoids, making it a flexible option in many routines.

Potential Side Effects/Adverse Reactions

Reactions to topical Polyglyceryl-10 Dipalmitate differ from person to person. The points below list potential side effects but most users will not experience them when the ingredient is used correctly in a well-formulated product.

  • Mild redness or itching if the skin is already compromised
  • Rare allergic contact dermatitis for individuals sensitive to glycerin derivatives
  • Temporary clogged pores or small breakouts in those highly prone to acne when used in very rich products
  • Eye stinging if a balm or cleanser containing it is rubbed directly into the eyes

If any unwanted reaction occurs stop using the product and consult a healthcare professional if symptoms persist.

Comedogenic Rating

Rating: 2 out of 5. Although Polyglyceryl-10 Dipalmitate contains palmitic acid groups that can be mildly pore clogging in their free form, the esterified structure and its use at low concentrations reduce that risk. Most people, including those with combination or slightly oily skin, experience no extra breakouts. Acne-prone users who react easily to fatty esters might still notice congestion in richer formulas, so they may prefer lightweight products featuring this ingredient.

No data suggest it interferes with active acne treatments or makes blackheads worse, and it rinses away cleanly in cleansing balms when removed with water.

Summary

Polyglyceryl-10 Dipalmitate is mainly an emollient and emulsifier. Its long polyglycerin backbone attracts water while the palmitic acid tails bond with oils, letting it bridge the two phases and leave a soft cushioned feel on skin without a heavy film. That dual action keeps creams stable, spreads actives evenly and smooths dry patches.

It is moderately popular in modern clean beauty lines and baby care where gentle, plant-based ingredients are valued, though it is still less common than classic emulsifiers like glyceryl stearate.

Overall safety is high with very few reports of irritation or allergies. While most users can apply it confidently, doing a small patch test with any new product is always a smart habit.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Get the latest beauty news, top product recommendations & brand-exclusive discount codes direct to your inbox.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Search