Polyglyceryl-10 Isostearate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polyglyceryl-10 Isostearate?

Polyglyceryl-10 Isostearate is an ester created by linking ten glycerin units to isostearic acid, a fatty acid usually sourced from plant oils like coconut, soybean or rapeseed. Because both building blocks come from renewable plants the ingredient is often described as naturally derived and readily biodegradable.

The move toward gentle, PEG-free and environmentally friendly emulsifiers in the early 2000s opened the door for polyglyceryl esters like this one. Brands were looking for milder alternatives to traditional surfactants and found that coupling multi-unit glycerin with fatty acids produced ingredients that are both skin friendly and effective. Today many formulators rely on Polyglyceryl-10 Isostearate as a workhorse emulsifier in modern clean beauty lines.

Manufacturing starts with food-grade glycerin that is heated to create a chain of roughly ten glycerin units, known as polyglycerin-10. This chain is then reacted with isostearic acid in a controlled process called esterification. The result is a clear to pale yellow liquid that dissolves easily in oils yet disperses in water, making it ideal for creating stable oil-in-water or water-in-oil formulas.

You will most often see Polyglyceryl-10 Isostearate in cleansing oils and balms, micellar waters, makeup removers, lightweight moisturizers, sunscreens, baby lotions and sheet mask serums. Its ability to keep oil and water blended while leaving a soft after-feel makes it popular in products designed for daily use and sensitive skin.

Polyglyceryl-10 Isostearate’s Cosmetic Benefits/Uses

This ingredient serves one main purpose in skincare and makeup formulas

Polyglyceryl-10 Isostearate functions as a skin-conditioning agent, meaning it helps keep the skin surface soft, supple and hydrated. By forming a light film it reduces moisture loss, improves the spreadability of creams and adds a silky finish without clogging pores or leaving a greasy residue.

Who Can Use Polyglyceryl-10 Isostearate

Because it is mild lightweight and non clogging Polyglyceryl-10 Isostearate works well for almost every skin type including dry sensitive oily and combination. It adds softness without heaviness so those prone to breakouts usually tolerate it just fine. People with very compromised or allergy prone skin should still keep an eye on how their skin feels since any ingredient can be a trigger for some individuals.

The raw materials come from plant oils and glycerin so the ingredient is suitable for vegans and vegetarians. No animal derived substances are used during manufacturing.

Current safety data show no issues for pregnant or breastfeeding women when the ingredient is used as intended in cosmetics. That said this is not medical advice and anyone who is pregnant or nursing should review all skincare products with a healthcare provider to be certain they fit personal health needs.

Polyglyceryl-10 Isostearate does not increase the skin’s sensitivity to sunlight and can be used alongside day creams or sunscreens without special precautions.

Potential Side Effects/Adverse Reactions

Side effects and reactions to the topical use of Polyglyceryl-10 Isostearate can vary from person to person. The following is a list of potential but unlikely issues. When used in properly formulated products most people experience none of these problems.

  • Mild redness or irritation in extremely sensitive skin
  • Rare allergic contact dermatitis leading to itching or small bumps
  • Temporary stinging if the product inadvertently gets into the eyes
  • Very slight chance of pore congestion in individuals highly prone to comedones

If any negative reaction occurs discontinue use and consult a healthcare professional or dermatologist for guidance.

Comedogenic Rating

Rating: 1 out of 5

Polyglyceryl-10 Isostearate is largely made of glycerin units that attract water combined with a branched fatty acid that is less likely to pack tightly in pores. This structure lets it condition skin and keep formulas stable without forming the heavy occlusive film linked to breakouts. Most user reports and lab data show a very low tendency to clog pores.

Because of this low rating it is generally suitable for people who are prone to acne or frequent breakouts.

As with any ingredient the finished product’s overall formula and the user’s unique skin chemistry also play a role in whether pimples appear.

Summary

Polyglyceryl-10 Isostearate is a plant derived ester that acts as a mild emulsifier and skin conditioning agent. It binds oil and water so creams stay smooth while leaving a soft hydrated feel on the skin.

Its ease of use, biodegradability and gentle touch have made it popular in modern clean beauty lines from micellar waters to baby lotions though it is still less common than classic emulsifiers like polysorbates.

Current research and decades of cosmetic use point to an excellent safety profile with only rare irritation or allergy. Still it is smart to patch test any new product to be sure it suits your individual skin.

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