Polyglyceryl-10 Nonaisostearate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polyglyceryl-10 Nonaisostearate?

Polyglyceryl-10 Nonaisostearate is a plant-derived ingredient created by linking ten glycerin units (called decaglycerol) and then attaching nine molecules of isostearic acid, a fatty acid that also comes from vegetable oils. The result is a mild, oil-loving yet water-friendly substance that blends smoothly into skin care formulas.

Scientists started working with polyglycerol esters in the late 1990s as brands searched for gentler alternatives to traditional PEG emulsifiers. Over time they found that this particular nonaester offered a good balance of skin comfort and formula stability, so it earned a spot in modern clean beauty products.

Manufacturers first heat glycerin from sources like coconut or rapeseed oil so the molecules join into a longer chain. They then react this chain with purified isostearic acid, also taken from plant oils. The finished ingredient is a soft, waxy liquid that disperses easily in both water-rich and oil-rich mixes, making it handy for many product types.

You will often see Polyglyceryl-10 Nonaisostearate in face and body moisturizers, lotions, creamy cleansers, sheet masks, lightweight serums, sunscreens, baby care formulas and even makeup like foundations or BB creams where a smooth, non-greasy feel is important.

Polyglyceryl-10 Nonaisostearate’s Cosmetic Benefits/Uses

This ingredient is mainly valued for one key role in skin care products.

Skin conditioning: It helps keep skin soft, smooth and hydrated by forming a light film that locks in moisture without a heavy or sticky after-feel. Its plant oil roots add a touch of fatty acids that support the skin barrier, so formulas feel comforting and suit sensitive or dry skin types.

Who Can Use Polyglyceryl-10 Nonaisostearate

This gentle, plant based ester suits nearly every skin type. Dry and sensitive complexions appreciate its light occlusive film that reduces moisture loss while oily or combination skin benefits from its non greasy texture that will not feel heavy or clog pores. Those with mature or compromised barriers can also find it soothing because the fatty acid content helps reinforce surface lipids. At this time there are no known reasons it would be unsuitable for any specific skin type.

Because it is sourced entirely from vegetable glycerin and plant derived isostearic acid, the ingredient is appropriate for vegans and vegetarians who avoid animal by-products in their personal care.

No research points to hormonal or developmental concerns, so products containing Polyglyceryl-10 Nonaisostearate are generally considered safe for pregnant or breastfeeding women. This is not medical advice and anyone who is expecting or nursing should review all skincare choices with a health professional before use.

The molecule does not make skin more sensitive to sunlight, so it is not classified as a photosensitizer. It can be worn day or night without special UV precautions beyond normal sunscreen habits.

Potential Side Effects/Adverse Reactions

Reactions to topical Polyglyceryl-10 Nonaisostearate differ from person to person. The list below covers potential side effects but most users will not experience them when the ingredient is properly formulated and used as directed.

  • Mild redness or irritation
  • Transient stinging on highly reactive skin
  • Contact allergy in individuals sensitive to glycerin derivatives

If any discomfort, persistent redness or swelling occurs stop use and consult a qualified healthcare provider.

Comedogenic Rating

Rating: 1/5. Polyglyceryl-10 Nonaisostearate is built from a branched fatty acid that resists tight packing in pores and a highly water-friendly polyglycerin chain, so it spreads thinly and rinses away more easily than heavier oils. Most formulators use it at low to moderate levels, which further limits any pore-blocking risk.

Because of this low rating it is generally considered suitable for people who are prone to acne or breakouts, especially when included in light lotions, gels or cleansers.

Keep in mind overall formula design, cleansing habits and individual skin chemistry also play a role in whether a product triggers congestion.

Summary

Polyglyceryl-10 Nonaisostearate is mainly a skin-conditioning agent that leaves a soft, smooth feel while helping lock water into the outer layer. Its unique mix of oil-loving and water-loving parts lets it sit comfortably on the skin without a greasy after-touch, supporting the barrier and boosting the sensory profile of creams, lotions and even makeup.

The ingredient shows up most often in clean beauty and baby-care lines but remains less common than classic emulsifiers, so it still feels like a specialty choice for brands that want a plant-based gentle touch.

Current data points to a high margin of safety with very rare irritation or allergy reports. Nonetheless every skin is different so patch testing a new product for a couple of days is always a smart precaution.

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