Polyglyceryl-10 Tetraoleate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polyglyceryl-10 Tetraoleate?

Polyglyceryl-10 Tetraoleate is a plant-derived ingredient created by linking ten glycerin units (decaglycerol) and then attaching four oleic acid molecules obtained from natural fats like olive or sunflower oil. The result is a mild, oil-soluble compound that acts a bit like a gentle surfactant yet feels more like a lightweight oil on the skin.

This material grew in popularity during the early 2000s when formulators began searching for alternatives to traditional PEG emulsifiers. By using glycerin, a familiar skin-friendly humectant, chemists could craft an emulsifier that is biodegradable and better tolerated by sensitive skin. Today it appears in a wide range of clean beauty and natural-leaning products.

Manufacturing involves a two-step process. First glycerin is heated under alkaline conditions to form a “poly” chain of ten units. Next the long chain is reacted with oleic acid to form ester bonds, producing a stable liquid that dissolves both oil and water phases.

You will most often spot Polyglyceryl-10 Tetraoleate in cleansing balms, creamy face washes, makeup removers, nourishing masks, baby lotions, lightweight moisturizers and soothing after-sun gels where a non-greasy skin finish is desired.

Polyglyceryl-10 Tetraoleate’s Cosmetic Benefits/Uses

The main role of Polyglyceryl-10 Tetraoleate in skincare is skin conditioning, meaning it helps soften and smooth the surface while supporting the skin’s protective barrier. Because it is derived from glycerin it also retains a touch of humectant character, pulling in water to keep formulas from feeling overly oily and leaving skin comfortably hydrated.

Who Can Use Polyglyceryl-10 Tetraoleate

This ingredient is generally well tolerated by all skin types including dry, normal, combination and oily. Its lightweight emollient feel makes it especially helpful for dehydrated or sensitive skin because it conditions without leaving a heavy residue. Extremely acne-prone users might wish to monitor how their skin responds, as with any new emollient, but the molecule itself is considered low clogging and non-greasy.

Polyglyceryl-10 Tetraoleate is produced from plant glycerin and plant-derived oleic acid so it is suitable for both vegetarians and vegans. No animal-sourced materials are needed in its manufacture and it is not typically tested on animals when used in certified cruelty-free formulations.

Current research shows no specific concerns for pregnant or breastfeeding women when this ingredient is applied topically. That said this information is not medical advice and anyone who is expecting or nursing should run all skincare products past a qualified doctor just to be safe.

The ingredient does not make skin more sensitive to sunlight and there is no known interaction with UV exposure. It is also odourless and free of essential oils making it a good choice for those avoiding fragrance.

Potential Side Effects/Adverse Reactions

Responses to topical Polyglyceryl-10 Tetraoleate can vary from person to person. The points below list potential side effects yet they are uncommon when the ingredient is used at standard levels by reputable manufacturers.

  • Mild redness or irritation in very sensitive skin
  • Rare allergic contact dermatitis for individuals reactive to oleic acid derivatives
  • Temporary stinging if applied to broken or compromised skin
  • Eye irritation if the product accidentally gets into the eyes
  • Occasional surface breakouts in users extremely prone to congestion

If any negative reaction occurs discontinue use and seek advice from a healthcare professional

Comedogenic Rating

Rating: 1/5 (low)

Even though Polyglyceryl-10 Tetraoleate is built from oleic acid, once that fatty acid is ester-linked to the polyglycerin backbone its tendency to clog pores drops sharply. The molecule is large, lightweight and has a partially water-loving structure that prevents it from packing tightly inside pores. It is therefore unlikely to trigger breakouts for most users and is generally considered suitable for acne-prone skin.

Keep in mind overall formulation matters: pairing this ester with heavy oils or waxes can still make a product feel richer and potentially more pore-blocking than the ingredient alone.

Summary

Polyglyceryl-10 Tetraoleate is a plant-derived skin conditioner that softens, smooths and subtly hydrates by combining the humectant nature of glycerin with the silkiness of oleic acid. Its amphiphilic structure also lets it act like a gentle emulsifier, helping water and oil mingle so formulas stay stable and feel light on the skin.

The ingredient enjoys steady popularity in clean beauty cleansers, balms, masks and baby care products thanks to its mildness and biodegradability, though it has not reached the mainstream fame of classic emulsifiers like polysorbates.

Safety studies and years of use show it to be low risk for irritation or sensitization. Still, everyone’s skin is unique so it is wise to patch test any new product that contains Polyglyceryl-10 Tetraoleate before adding it to a regular routine.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.