Polyglyceryl-2 Diisostearate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
Share:
Inside this article:

We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polyglyceryl-2 Diisostearate?

Polyglyceryl-2 Diisostearate is a plant-derived ingredient made by joining diglycerol, a small chain of glycerin molecules, with two units of isostearic acid that usually comes from vegetable oils like rapeseed or canola. This pairing creates a mild oil-friendly molecule known for helping water and oil mix. Interest in the ingredient grew in the early 2000s when brands looked for alternatives to polyethylene glycol (PEG) emulsifiers and wanted options that fit clean-beauty claims. To produce it, manufacturers heat diglycerol with isostearic acid in the presence of a food-grade catalyst, then purify the result. The finished material is liquid or soft solid and easily blends into cosmetic bases. You will most often spot it in creams, lotions, foundations, lipsticks, cleansing balms, masks, sunscreens, baby care products and formulas sold for sensitive skin.

Polyglyceryl-2 Diisostearate’s Cosmetic Benefits/Uses

The main value of Polyglyceryl-2 Diisostearate lies in its role as an emulsifier. By sitting at the interface of oil and water it allows formulators to create smooth stable mixtures that look appealing feel silky and stay blended over time. The result is cosmetics that spread evenly without separating which improves texture shelf life and overall user experience.

Who Can Use Polyglyceryl-2 Diisostearate

This emulsifier is considered gentle enough for all skin types including dry sensitive oily and combination skin. Because it is lightweight and low on the pore-clogging scale it rarely causes problems for acne-prone users, though extremely reactive skin should still monitor any new product for changes.

Polyglyceryl-2 Diisostearate is manufactured from plant-based glycerin and vegetable-sourced isostearic acid so it is suitable for vegans and vegetarians provided the finished formula does not incorporate animal-derived additives.

Current cosmetic safety assessments show no specific risks for women who are pregnant or breastfeeding when this ingredient is used topically at normal concentrations. Still this is not medical advice and anyone who is expecting or nursing should review any skincare product with a qualified healthcare professional to stay on the safe side.

The ingredient does not make skin more sensitive to sunlight and does not react with UV filters or common active ingredients, so no extra sun precautions are needed other than regular daily sunscreen use.

Potential Side Effects/Adverse Reactions

Responses to topical Polyglyceryl-2 Diisostearate vary from person to person. The effects listed below are possible yet unlikely for most users when the ingredient is formulated and used correctly.

  • Mild skin irritation
  • Redness or itching in individuals with an allergy to fatty acid derivatives
  • Temporary breakout or clogged pores in very acne-prone skin if the product contains a high overall oil load
  • Eye irritation if the raw material contacts the eyes before being diluted in a finished product

If any uncomfortable reaction occurs stop using the product and consult a healthcare professional if symptoms persist or worsen.

Comedogenic Rating

Rating: 1 / 5

Polyglyceryl-2 Diisostearate is made from small glycerin units and branched isostearic acid that stay largely on the surface of skin and rinse away or absorb without forming a heavy film. Studies and practical use show very few reports of clogged pores, so it earns a low score of 1 rather than a perfect 0 since any oil-compatible material can theoretically trap debris when used in very thick formulas.

Because of this low rating most people who struggle with acne or frequent breakouts can usually use products containing Polyglyceryl-2 Diisostearate without trouble.

Keep in mind that overall product design matters; a lightweight serum with this emulsifier is far less likely to block pores than a rich balm packed with waxes and butters.

Summary

Polyglyceryl-2 Diisostearate is an oil-loving emulsifier that lets water and oil blend to create smooth stable creams lotions makeup and cleansing products. Its plant origin clean-beauty appeal and mild profile have made it a staple in natural and sensitive-skin lines although it is not as famous as long-standing PEG emulsifiers.

Safety reviews find it non irritating, non sensitizing and largely non comedogenic at typical use levels. While reactions are rare every skin is different, so it is wise to patch test any new product that features this ingredient before full-face use.

Was this article helpful?
More from Glooshi:
ADVERTISEMENT
Get all our top headlines in beauty.
Delivered right to your inbox each week. Zero spam, all goodness, opt-out at anytime.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send good feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Send bad feedback:

All feedback is greatly appreciated, anonymous, and will be used to improve the quality of our articles.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.