Polyglyceryl-6 Palmitate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polyglyceryl-6 Palmitate?

Polyglyceryl-6 Palmitate is a plant-derived ingredient made by joining six glycerin units and linking them with palmitic acid, a fatty acid that can be sourced from palm or coconut oil. The result is a mild, partly fatty molecule that loves both water and oil, making it useful in skin care. It first caught the eye of formulators in the early 2000s as brands looked for alternatives to petroleum-based surfactants. Because it is made from renewable raw materials and breaks down easily in the environment, it fits well with today’s push for greener beauty.

The production process starts with glycerin, which is heated under safe food-grade conditions to form a short chain called polyglycerin-6. This chain is then reacted with palmitic acid. The controlled reaction gives a uniform material that holds a cosmetic grade and meets safety rules in most regions.

You will most often find Polyglyceryl-6 Palmitate in moisturizers, face masks, day creams, body lotions, gentle cleansers and hydrating makeup such as BB creams or tinted moisturizers. Its dual love for water and oil lets it replace harsher emulsifiers, so it is especially common in products aimed at sensitive skin.

Polyglyceryl-6 Palmitate’s Cosmetic Benefits/Uses

This ingredient brings two main perks to a formula

  • Emollient: It softens and smooths the skin surface by creating a light, breathable film that traps water and helps reduce roughness. This leaves skin feeling supple without a greasy afterfeel.
  • Emulsifying: Its water-and-oil friendly nature keeps oil droplets evenly spread in a lotion or cream. This stabilizes the mix so the product stays creamy, spreads easily and delivers active ingredients evenly.

Who Can Use Polyglyceryl-6 Palmitate

Thanks to its mild nature and light skin feel, Polyglyceryl-6 Palmitate suits most skin types including normal, dry, combination and sensitive skin. Its low oiliness means it generally works for oily or breakout-prone skin too, though very acne-prone users may prefer formulas where it is blended with lighter esters.

The ingredient is typically sourced from plant glycerin and palm or coconut fatty acids, so it is usually considered vegan and vegetarian friendly. If a brand chooses animal-derived palmitic acid it should state this, so anyone following a strict plant-based lifestyle may want to confirm the source with the manufacturer.

Current safety assessments have not flagged any risk for pregnant or breastfeeding women when the ingredient is used in cosmetics. This is not medical advice and anyone who is pregnant or nursing should still run their whole skincare routine past a healthcare professional.

Polyglyceryl-6 Palmitate is not known to cause photosensitivity and does not make skin more prone to sunburn.

Potential Side Effects/Adverse Reactions

Individual responses can vary. The effects listed below are possible rather than probable and most people will not notice any problems when the ingredient is used at standard cosmetic levels.

  • Mild skin irritation such as redness or itching in very sensitive users
  • Contact allergy in individuals already allergic to glycerin derivatives or fatty acids
  • Clogged pores or small breakouts if the finished formula is overly rich for the user’s skin type
  • Transient eye stinging if the product accidentally gets into the eyes

If any of the above reactions occur stop using the product and seek advice from a medical professional.

Comedogenic Rating

Rating: 2 / 5

On its own Polyglyceryl-6 Palmitate is largely water loving and forms a lightweight film, which keeps its pore clogging potential low. The palmitic acid part carries a moderate comedogenic reputation, yet the large polyglycerin backbone offsets this by making the overall molecule more water dispersible and less likely to pack into pores. Finished formulas that are very rich or blended with heavier butters can still tip the scale, so the context of the product matters.

Most people who are prone to acne or breakouts can usually tolerate this ingredient, especially when it appears in lightweight lotions or serums.

Formulators sometimes pair it with even lighter esters or silicone alternatives to make sure the end product stays friendly to oily skin. Checking the entire ingredient list is therefore more useful than focusing on this single component.

Summary

Polyglyceryl-6 Palmitate works mainly as an emollient and emulsifier. Its polyglycerin side binds to water while the palmitic acid tail loves oils, letting it sit at the water-oil boundary where it softens skin and keeps creams evenly blended. Because it is plant sourced biodegradable and gentle it has gained solid traction in clean beauty and sensitive skin lines, though it is still less common than older petro-based emulsifiers.

Safety data show a very low irritation and allergen profile, making it suitable for most users including those who are pregnant or breastfeeding. That said skin is personal, so doing a quick patch test when trying any new product is always the safest approach.

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