Polylysine Hbr: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polylysine Hbr?

Polylysine Hbr is the hydrobromide salt of polylysine, a chain of the naturally occurring amino acid lysine. It is usually produced by fermenting a safe strain of the soil bacterium Streptomyces albulus, which churns out long strings of lysine units. After fermentation the polymer is purified and reacted with a small amount of hydrobromic acid to create the stable hydrobromide form used in cosmetics.

The ingredient first drew attention in the food industry as a natural preservative, then formulators noticed that its film-forming and conditioning traits could help hair look smoother and feel softer. Today it appears in rinse-off conditioners, leave-in creams, hair masks, anti-frizz serums and some styling products aimed at boosting softness or managing flyaways. It is water-soluble, plays well with most common hair-care ingredients and can be added to formulas at low to moderate levels without changing the look or feel of the final product.

Polylysine Hbr’s Cosmetic Benefits/Uses

In personal-care products polylysine Hbr serves a single key role.

Hair conditioning: The polymer forms a light, invisible layer along the hair shaft. This coating helps smooth rough cuticles, reduces static and makes strands easier to comb. The result is hair that feels softer, looks shinier and is less prone to breakage from everyday styling.

Who Can Use Polylysine Hbr

Because it is water-soluble and lightweight, Polylysine Hbr suits virtually every hair type, from straight and fine to coarse and curly. Oily, balanced and dry scalps all tend to tolerate it well since it does not leave an occlusive film or clog follicles. There are no specific skin or scalp types that need to steer clear of this ingredient unless an individual already knows they are sensitive to lysine-based compounds.

Polylysine Hbr is produced by fermenting bacteria and contains no animal-derived material, so it is considered vegan and vegetarian friendly.

Current safety data show no known risks for pregnant or breastfeeding women when Polylysine Hbr is applied topically in cosmetic amounts. That said this information is not medical advice and anyone who is expecting or nursing should run new hair or scalp products past a qualified healthcare professional to be on the safe side.

The ingredient does not cause photosensitivity and will not make hair or scalp more prone to sun damage. It also plays nicely with common color-protecting systems, making it suitable for color-treated hair.

Potential Side Effects/Adverse Reactions

Side effects and reactions to the topical use of Polylysine Hbr can vary from person to person. The issues listed below are uncommon and most users will not experience them when the ingredient is formulated and used correctly.

  • Mild scalp irritation such as itching or redness in very sensitive individuals
  • Allergic contact dermatitis in people already allergic to lysine-based compounds
  • Product buildup that leaves hair feeling weighed down if used in very high concentrations or layered with heavy styling products
  • Dry ends if combined with strong clarifying shampoos and not balanced with emollients

If any irritation or unexpected reaction occurs stop using the product and consult a healthcare professional or dermatologist.

Comedogenic Rating

Rating: 0/5. Polylysine Hbr is a large, water-soluble polymer that rinses away easily and does not penetrate or block pores, so it is considered non-comedogenic.

Suitable for acne-prone or breakout-prone skin since it is unlikely to trigger clogged pores.

Because it is primarily used in rinse-off or lightweight leave-in hair products, any residue that reaches facial skin is minimal and quickly removed during normal cleansing.

Summary

Polylysine Hbr is a vegan, fermentation-derived polymer used in hair care to form a thin conditioning film that smooths cuticles, tames static and makes strands feel softer and look shinier. It works by laying down a lightweight, water-soluble coating that improves slip and reduces breakage.

The ingredient is still a niche choice compared with classic conditioners like silicones or quats, but its natural origin and easy rinse-off profile are helping it gain quiet popularity in clean and eco-focused formulas.

Current data show Polylysine Hbr to be low risk for irritation or toxicity when used in cosmetic concentrations, with virtually no comedogenic concern. As with any new personal care product, a quick patch test is a smart precaution to confirm individual tolerance.

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