Polypropanediol-5/Polyglycerin-3 Copolymer Sesquistearate: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polypropanediol-5/Polyglycerin-3 Copolymer Sesquistearate?

Polypropanediol-5/Polyglycerin-3 Copolymer Sesquistearate is a lab made polymer that starts with two sugar derived building blocks: propanediol and glycerin. Scientists first link five units of propanediol to form polypropanediol-5, then join it with a short chain of three glycerin units to create a flexible block copolymer. This structure is finished off by reacting it with stearic acid, a fatty acid usually sourced from coconut or palm oil, giving the material its cleansing and texture enhancing abilities.

The ingredient was developed in the past decade as brands looked for plant based alternatives to older petrochemical emulsifiers. Thanks to its skin friendly profile and ease of use in cold or hot processing, formulators quickly adopted it in gentle cleansers, moisturizing lotions, creamy masks, lightweight serums, foundations and even some sunscreens.

Production follows standard cosmetic good manufacturing practice. The propanediol and glycerin units are condensed under controlled heat with a food grade catalyst, the resulting polymer is purified, then esterified with stearic acid to create a balanced mix of monoesters and diesters that pour easily into cosmetic batches.

Polypropanediol-5/Polyglycerin-3 Copolymer Sesquistearate’s Cosmetic Benefits/Uses

This multi-tasking polymer offers two main functions inside a formula

  • Cleansing Its fatty side chains bind to oils so it can lift away sweat, sebum and makeup without stripping the skin, making it popular in gentle face washes and micellar products.
  • Emulsifying It helps water and oil mix smoothly, giving creams and lotions a uniform, stable texture that feels light and non greasy while preventing the formula from separating over time.

Who Can Use Polypropanediol-5/Polyglycerin-3 Copolymer Sesquistearate

This ingredient is gentle and non clogging so it suits most skin types including dry, normal, combination oily and even sensitive skin. Because it cleans without stripping and keeps formulas light it rarely causes tightness on dry skin or greasiness on oily skin. There are no known issues for acne-prone users although, as with any fatty ester, very reactive skin should observe how it feels in daily use.

Polypropanediol and glycerin come from plant sugars and the stearic acid used today is usually sourced from coconut or palm so products that state a vegetable origin can fit vegan and vegetarian lifestyles. If animal origin matters the brand should confirm the source of its stearic acid.

No studies flag the ingredient as problematic for women who are pregnant or breastfeeding. It sits on the surface and is not expected to enter the bloodstream in meaningful amounts. Still this is not medical advice and anyone who is pregnant or nursing should show the full product list to a doctor before adding it to a routine.

The molecule does not make skin more sensitive to sunlight so there is no added risk of sunburn. It also plays well with common actives like vitamin C, niacinamide or retinol and does not lower their effectiveness.

Potential Side Effects/Adverse Reactions

Reactions to topical Polypropanediol-5/Polyglycerin-3 Copolymer Sesquistearate vary from person to person. The effects listed below are possible yet unlikely for most users when the final product is well made and used as directed.

  • Mild skin irritation some people may notice temporary redness or stinging especially on broken or freshly shaved skin
  • Allergic contact dermatitis very rare but can appear in individuals with a specific sensitivity to fatty esters or residual catalysts
  • Eye irritation possible watering or burning if the raw ingredient or a cleanser containing it gets into the eyes
  • Excessive dryness overuse in high foaming cleansers could leave skin feeling tight particularly in low humidity climates

If any negative effect occurs stop using the product and consult a health professional.

Comedogenic Rating

Rating: 1 / 5

This polymer is a large surface-active molecule that mostly stays on the skin’s surface where it helps mix oil and water. Its bulky size and balanced fatty chain length mean it does not slip easily into pores so the clogging risk is very low. A rating of 1 reflects that rare individuals who react to fatty esters could still notice congestion yet the vast majority will not.

In practical terms it is considered fine for people who are prone to acne or breakouts.

Because it is usually used at low levels and is rinsed off in many cleansers it is even less likely to contribute to clogged pores compared with leave-on fatty esters.

Summary

Polypropanediol-5/Polyglycerin-3 Copolymer Sesquistearate is a plant-derived polymer that cleans and emulsifies. The stearic acid part grabs oil and dirt so they can be washed away while the propanediol-glycerin backbone keeps water and oil blended, giving lotions and cleansers a smooth stable feel.

It has gained steady but not superstar popularity because it offers a gentle, vegan friendly alternative to older emulsifiers without needing special handling, making life easier for formulators who want mild textures.

Safety data and real-world use show it is low risk for irritation or pore clogging which is why it appears in products aimed at sensitive and combination skin. Still every skin is unique so it is smart to patch test any new product that lists this ingredient before fully adding it to your routine.

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