Polyquaternium-111: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polyquaternium-111?

Polyquaternium-111 is a synthetic polymer created by combining acrylic acid, dimethyl diallyl ammonium chloride and hydroxyisopropyl acrylate. This blend forms a quaternary ammonium salt, meaning it carries a positive charge that readily bonds with the negatively charged surface of hair. The ingredient was introduced in the late 1990s when formulators searched for gentler, water-soluble conditioning agents that would not leave heavy buildup. Production involves controlled polymerization in water, followed by purification and drying into a stable powder or viscous liquid that dissolves easily in cosmetic bases.

You will most often see Polyquaternium-111 in rinse-off and leave-on hair products such as shampoos, conditioners, masks, styling creams, mousses and serums. Its ability to combat static and smooth the cuticle also makes it a helpful addition to anti-frizz sprays and heat protectants.

Polyquaternium-111’s Cosmetic Benefits/Uses

Formulators reach for Polyquaternium-111 because it offers two standout functions that noticeably improve the look and feel of hair.

  • Antistatic: The polymer’s positive charge neutralizes static electricity on hair fibers, cutting down on flyaways and making strands easier to manage during styling.
  • Hair conditioning: It forms a light, invisible film that smooths the cuticle, boosts softness and adds slip for easier detangling without weighing hair down.

Who Can Use Polyquaternium-111

Because Polyquaternium-111 is water soluble and designed to rinse clean, it works well for virtually every hair and scalp type including oily, dry, fine, thick and chemically treated. It does not clog pores or leave heavy residue so even those prone to scalp breakouts usually tolerate it.

The polymer is fully synthetic and contains no animal derived materials, making it suitable for vegans and vegetarians.

Current safety data show no known risks for women who are pregnant or breastfeeding when the ingredient is used as directed in rinse-off or leave-on hair products. This is not medical advice; anyone who is expecting or nursing should review all personal care products with a healthcare professional to be sure they meet individual needs.

Polyquaternium-111 is not linked to photosensitivity. It can be used in daytime or nighttime formulas without increasing the skin or scalp’s sensitivity to sunlight.

Potential Side Effects/Adverse Reactions

Responses to topical Polyquaternium-111 vary from person to person. The points below outline possible side effects, though most people will not notice any problems when using properly formulated products.

  • Mild scalp irritation
  • Redness or itching linked to allergy to quaternary ammonium compounds
  • Temporary eye stinging if the product accidentally gets into the eyes
  • Product buildup and limp hair when extremely high concentrations are used or when hair is not rinsed thoroughly

If any uncomfortable reaction occurs stop using the product and consult a healthcare professional or dermatologist for guidance.

Comedogenic Rating

Rating: 0-1 out of 5

Polyquaternium-111 is highly water soluble and forms a light film that rinses away with normal shampooing. Its large molecular size keeps it on the surface of hair instead of sinking into skin or blocking pores, so it has little to no chance of causing breakouts. Because of this it is generally suitable for people who are prone to acne or scalp blemishes.

As with any styling or leave-on product, buildup is possible if very heavy layers are applied day after day without proper cleansing. Regular washing prevents this and keeps the low clogging risk close to zero.

Summary

Polyquaternium-111 is mainly used to stop static and condition hair. The positive charge in its structure sticks to the hair shaft, smooths rough cuticles, cuts down on flyaways and gives strands a soft slippery feel that makes detangling easier.

While not as famous as silicone heavyweights like dimethicone, this polymer has carved out a steady spot in modern shampoos, conditioners and styling sprays because it offers similar smoothing benefits yet rinses out more easily.

Current research shows it is a safe ingredient for most users and irritation reports are rare. Still, skin and hair differ from person to person so it is wise to patch test any new product that contains Polyquaternium-111 before adding it to your regular routine.

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