What Is Polyquaternium-27?
Polyquaternium-27 is a synthetic polymer belonging to the large polyquaternium family, a group of quaternary ammonium compounds prized for their positive charge. Made by reacting dimethylamine derivatives with epichlorohydrin and various diacid linkers, the process yields long chains peppered with quaternary ammonium groups that readily bind to negatively charged surfaces like hair and skin. First introduced in the late 1980s as formulators searched for gentler alternatives to traditional cationic surfactants, it quickly gained traction in personal care labs thanks to its ability to create smooth, weightless films.
The ingredient is manufactured in water as a viscous, clear solution then purified to remove residual salts. Because it is water soluble and compatible with a wide pH range, chemists can drop it into cold or hot phases without complicated processing steps, making it a cost-effective choice for mass-market and premium lines alike.
You will most often spot Polyquaternium-27 in rinse-off and leave-on hair conditioners, styling gels, mousses, anti-frizz serums, 2-in-1 shampoos, skin-hydrating sheet masks, lightweight facial moisturizers and long-wear makeup where a flexible, breathable film is desirable.
Polyquaternium-27’s Cosmetic Benefits/Uses
Its dual functionality lets it play several supportive roles in everyday beauty staples
- Antistatic: The positive charge neutralizes the static electricity that builds up on hair fibers or fabric-like sheet masks. This reduces flyaways, makes detangling easier and leaves hair looking sleeker and more controlled
- Film forming: It lays down a thin, transparent coating that locks in moisture, bolsters shine, enhances product spreadability and improves the longevity of color cosmetics or styling hold without a stiff feel
Who Can Use Polyquaternium-27
Thanks to its gentle, non-sensitizing profile, Polyquaternium-27 is generally suitable for most skin and hair types including dry, normal and oily. People with highly reactive or allergy-prone skin can usually tolerate it as well, although anyone with a known sensitivity to quaternary ammonium compounds should steer clear
The ingredient is synthesized entirely from petrochemical feedstocks and contains no animal-derived components so it aligns with vegan and vegetarian lifestyles. Brands that are cruelty-free often pair it with other plant-based ingredients without issue
Topical use during pregnancy or while breastfeeding is considered low risk because the large polymer molecules sit on the surface instead of penetrating deeply. This is not medical advice and pregnant or nursing individuals should get personalized guidance from a healthcare provider before adding any new product
Polyquaternium-27 does not cause photosensitivity, so daytime use requires no extra sun precautions beyond a daily SPF that most dermatologists already recommend
No other major restrictions are linked to this ingredient, making it a versatile choice for leave-on and rinse-off formulas alike
Potential Side Effects/Adverse Reactions
Reactions to topical Polyquaternium-27 differ from person to person. The points below outline potential side effects, but most users will never encounter them when the ingredient is formulated and used correctly
- Mild skin or scalp irritation such as redness or itching
- Contact dermatitis in individuals allergic to quaternary ammonium compounds
- Eye stinging if the product accidentally runs into the eyes before rinsing
- Product buildup that can weigh hair down when high concentrations are used frequently without proper cleansing
If you experience any of these issues stop using the product and consult a medical professional or dermatologist for further advice
Comedogenic Rating
Rating: 1 / 5 (low likelihood of clogging pores)
Polyquaternium-27 is a large, water-soluble polymer that stays on the surface of skin rather than sinking into follicles. It forms a breathable film that rinses away easily, leaving minimal residue. Because it is not oily and has no fatty acid chains, it rarely contributes to blackheads or pimples.
Most acne-prone users can safely use products containing Polyquaternium-27 without seeing an uptick in breakouts. Those who apply multiple heavy leave-on layers may want to monitor for buildup, but issues are uncommon.
No data suggest heightened pore blockage when the ingredient is used at the low levels typical in hair conditioners and lightweight skin care.
Summary
Polyquaternium-27 delivers two main benefits: it neutralizes static so hair looks smoother and it creates an invisible film that locks in moisture, boosts shine and helps makeup or styling products stay put. The cationic charge lets the polymer cling to negatively charged hair and skin, while its flexible backbone keeps the coating light and comfortable.
Although not as famous as silicone heavyweights or newer plant-based polymers, Polyquaternium-27 quietly powers a wide range of mainstream shampoos, conditioners, gels and long-wear cosmetics thanks to its cost-effective performance and easy formulation.
Safety records show a low risk of irritation or pore clogging, so the ingredient is considered safe for routine use on most skin and hair types. As with any new product, doing a quick patch test helps confirm personal compatibility before full application.