Polyquaternium-55: What Is It, Cosmetic Uses, Benefits & Side Effects

Curious about this ingredient? In this article we're explaining exactly what it is and why it's used within cosmetic formulations.
Updated on: July 1, 2025
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We verify all information on this page using publicly available nomenclature standards from The Personal Care Products Council (PCPC), the European Commission's CosIng database and documentation provided directly by ingredient manufacturers. Our analysis is based on technical data from these sources to ensure accuracy and reliability.

What Is Polyquaternium-55?

Polyquaternium-55 is a synthetic, water-soluble polymer created by combining quaternized ammonium compounds with acrylamide and vinylpyrrolidone units. These building blocks are linked together to form a long chain that carries a positive charge, a feature that allows the polymer to cling to the negatively charged surface of hair. The first wave of quaternary polymers appeared in the 1970s when formulators sought alternatives to traditional setting resins that felt stiff or flaky. Over time chemists fine-tuned the ratio of monomers to improve hold while keeping hair touchable, which led to the development of Polyquaternium-55. Production starts with the controlled polymerization of its monomers in water, followed by purification steps that remove residual reactants and yield a clear viscous solution. Because it forms a flexible film once the water evaporates it is widely used in styling products such as gels, mousses, sprays, pomades, cream stylers and leave-in masks. Its gentle nature means it can also appear in conditioning shampoos and dual-purpose treatments that aim to shape hair while adding softness.

Polyquaternium-55’s Cosmetic Benefits/Uses

The ingredient’s main job in cosmetics is hair fixing. When applied, Polyquaternium-55 spreads over each strand and sets into a thin elastic film as the product dries. This film locks the desired style in place, resists humidity, reduces frizz and provides a lasting yet flexible hold. Because the polymer is positively charged it also smooths the hair cuticle, which can make styles look shinier and feel softer while cutting down on static flyaways.

Who Can Use Polyquaternium-55

Because Polyquaternium-55 is water soluble and forms a light flexible film it is suitable for all hair and scalp types, including dry, oily, sensitive and color-treated. Its cationic nature helps smooth the cuticle without sealing the scalp so it rarely weighs fine hair down or aggravates oiliness.

The polymer is made from fully synthetic starting materials and contains no animal by-products which makes it appropriate for both vegans and vegetarians. Manufacturers typically use plant or petroleum based feedstocks and no animal testing is required for leave-on hair products in many regions though individual brand policies may differ.

Current safety data show no systemic absorption through the skin or scalp so products containing Polyquaternium-55 are generally considered safe for those who are pregnant or breastfeeding. This is not medical advice. Anyone who is pregnant or nursing should review their routine with a qualified healthcare provider to be extra safe.

The ingredient does not make skin or hair more sensitive to sunlight and has no known impact on photosensitivity. It is also compatible with most common styling aids like silicones, proteins and plant oils so it fits easily into multi-step hair routines.

Potential Side Effects/Adverse Reactions

Reactions to topical Polyquaternium-55 differ from person to person. The points below cover possible side effects yet most people will not have any problems when the ingredient is used at normal levels in a well formulated product.

  • Mild scalp or skin irritation A small number of users may notice redness itching or a tingling sensation after application
  • Contact allergy Rare cases of allergic dermatitis have been reported with cationic polymers which can lead to rash or swelling
  • Product buildup Heavy or repeated application without proper cleansing can leave a film that makes hair feel coated or dull
  • Eye irritation If styling products accidentally get into the eyes users may experience stinging or watering
  • Flaking or white residue Overapplication in high humidity can cause the dried film to break and appear as flakes

If any negative reaction occurs discontinue use and seek advice from a medical professional or dermatologist.

Comedogenic Rating

Rating: 0 out of 5. Polyquaternium-55 is highly water soluble and its large molecular size keeps it on the surface where it is easily washed away, so it has almost no chance of blocking pores or forming comedones. Real-world reports do not link it to acne flare-ups.

The ingredient is therefore considered safe for acne-prone or breakout-prone users.

Because styling products can migrate to the hairline or forehead, washing the face and scalp thoroughly at the end of the day will remove any residue and keep skin clear.

Summary

Polyquaternium-55 is a positively charged polymer that forms a light flexible film over each strand which locks in style, tames frizz, boosts shine and cuts static, delivering reliable hold without stiffness. It clings to hair through ionic attraction so performance stays consistent even in humidity.

While not a headline ingredient, its balance of gentle feel and strong yet touchable hold keeps it in steady demand among formulators, so it often appears in gels, mousses, sprays and hybrid conditioning stylers.

Safety data and decades of use show a low risk profile with only occasional mild irritation reported. Still, it is smart to patch test any new product containing this polymer to confirm personal compatibility.

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